Cheap Flight Tickets from Harrisburg (MDT) to Knoxville (TYS), Starting at $197

Good to Know: Cheapest and Fastest MDT - TYS Flights

Useful information for finding best airline tickets from Harrisburg International to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$197

DL Delta Airlines • 1 stop • 6h 47m

Nov 04 – Nov 08

The cheapest round trip flight from Harrisburg to Knoxville (MDT-TYS-MDT) is currently $197

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Fastest Flight

5h 43m

The fastest nonstop flight from Harrisburg to Knoxville (MDT-TYS) takes 5h 43m

Top Airlines Flying from Harrisburg to Knoxville

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Harrisburg (MDT) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Harrisburg to Knoxville. Ideal for travelers with confirmed return itineraries.

Nov 04 - Nov 08, Economy
DL
Harrisburg → Knoxville
6h 47m
6:13 AM - 10:20 AM • 1 stop
DL
Harrisburg → Knoxville
7h 39m
9:12 AM - 2:11 PM • 1 stop
$197
Delta Airlines
Nov 04 - Nov 08, Economy
DL
Harrisburg → Knoxville
10h 49m
12:25 PM - 7:14 PM • 1 stop
DL
Harrisburg → Knoxville
5h 50m
7:09 AM - 10:59 AM • 1 stop
$197
Delta Airlines
Nov 04 - Nov 08, Economy
AA
Harrisburg → Knoxville
5h 58m
11:25 AM - 3:23 PM • 1 stop
AA
Harrisburg → Knoxville
6h 48m
8:49 AM - 12:57 PM • 1 stop
$263
American Airlines
Nov 04 - Nov 08, Economy
AA
Harrisburg → Knoxville
8h 43m
11:25 AM - 4:48 PM • 1 stop
AA
Harrisburg → Knoxville
5h 36m
1:42 PM - 5:18 PM • 1 stop
$263
American Airlines
Nov 04 - Nov 08, Economy
AA
Harrisburg → Knoxville
5h 43m
5:00 PM - 8:43 PM • 1 stop
AA
Harrisburg → Knoxville
8h 24m
3:55 PM - 8:59 PM • 1 stop
$263
American Airlines
Nov 04 - Nov 08, Economy
AA
Harrisburg → Knoxville
7h 10m
7:25 AM - 11:55 AM • 1 stop
AA
Harrisburg → Knoxville
5h 52m
11:06 AM - 2:58 PM • 1 stop
$263
American Airlines

Fly from Harrisburg to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Harrisburg to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Harrisburg to Knoxville Flights

What are the airports in Harrisburg?
MDT
What’s the most popular airline flying from MDT to TYS?
The most popular airline flying from Harrisburg to Knoxville are
Can I fly from MDT to TYS non-stop?
NO
Which airlines fly nonstop between Harrisburg and Knoxville?
The non-stop flights between Harrisburg and Knoxville are .
What’s the earliest departure time from MDT to TYS Airport?
The earliest flight leaves MDT at 6:13 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Harrisburg to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from MDT to TYS?
Read the fare rules of the Harrisburg to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Harrisburg and Knoxville?
operate flights between Harrisburg and Knoxville
How long does a flight from Harrisburg to Knoxville take?
It takes approximately 2 hour to fly non-stop from MDT to TYS, which is 496.77 miles by air.
Which airlines provide the cheapest flights from Harrisburg (MDT) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from MDT were found on DL : USD 197
Do I need a passport to fly between MDT and TYS?
No
What’s the latest departure time from MDT to TYS ?
The last flight leaves MDT at 5:00 pm

Harrisburg (MDT) to Knoxville (TYS): Airport Information

Origin Airport Harrisburg International , Harrisburg, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 497 miles

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