Cheap Flight Tickets from Orlando (MCO) to Knoxville (TYS), Starting at $101

Good to Know: Cheapest and Fastest MCO - TYS Flights

Useful information for finding best airline tickets from Orlando International to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$307

WN Southwest Airlines • 1 stop • 9h

Nov 25 – Nov 29

The cheapest round trip flight from Orlando to Knoxville (MCO-TYS-MCO) is currently $307

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Cheapest One way Flight

$101

WN Southwest Airlines • 2 stops • 25h

Oct 06

The cheapest one way flight from Orlando to Knoxville (MCO-TYS) is currently $101

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Cheapest Direct Flight

$302

WN Southwest Airlines • nonstop • 2h 35m

Nov 25

The cheapest nonstop flight from Orlando to Knoxville (MCO-TYS) is currently $302

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Fastest Flight

2h 30m

The fastest nonstop flight from Orlando to Knoxville (MCO-TYS) takes 2h 30m

Top Airlines Flying from Orlando to Knoxville

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

Latest Flight Deals from Orlando (MCO) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Orlando to Knoxville. Ideal for travelers with confirmed return itineraries.

Nov 25 - Nov 29, Economy
WN
Orlando → Knoxville
9h
6:25 AM - 12:05 PM • 1 stop
WN
Orlando → Knoxville
2h 25m
12:00 PM - 1:45 PM • nonstop
$307
Southwest Airlines
Nov 25 - Nov 29, Economy
WN
Orlando → Knoxville
9h 5m
4:55 PM - 10:40 PM • 1 stop
WN
Orlando → Knoxville
2h 25m
12:00 PM - 1:45 PM • nonstop
$307
Southwest Airlines
Nov 25 - Nov 29, Economy
WN
Orlando → Knoxville
9h
6:25 AM - 12:05 PM • 1 stop
WN
Orlando → Knoxville
9h 5m
6:35 AM - 12:20 PM • 2 stops
$312
Southwest Airlines
Nov 25 - Nov 29, Economy
DL
Orlando → Knoxville
6h 50m
9:45 AM - 1:55 PM • 1 stop
DL
Orlando → Knoxville
6h 45m
10:35 AM - 2:40 PM • 1 stop
$341
Delta Airlines
Nov 25 - Nov 29, Economy
WN
Orlando → Knoxville
11h 45m
3:35 PM - 10:40 PM • 2 stops
WN
Orlando → Knoxville
6h 40m
7:50 PM - 11:50 PM • 1 stop
$451
Southwest Airlines
Nov 25 - Nov 29, Economy
WN
Orlando → Knoxville
25h
10:50 PM - 1:50 PM • 2 stops
WN
Orlando → Knoxville
2h 25m
12:00 PM - 1:45 PM • nonstop
$559
Southwest Airlines

Fly from Orlando to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Orlando to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Orlando to Knoxville Flights

What are the airports in Orlando?
MCO
What’s the most popular airline flying from MCO to TYS?
The most popular airline flying from Orlando to Knoxville are
Can I fly from MCO to TYS non-stop?
Yes, you can fly MCO to TYS non-stop on
Which airlines fly nonstop between Orlando and Knoxville?
The non-stop flights between Orlando and Knoxville are .
What’s the earliest departure time from MCO to TYS Airport?
The earliest flight leaves MCO at 6:05 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Orlando to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from MCO to TYS?
Read the fare rules of the Orlando to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Orlando and Knoxville?
operate flights between Orlando and Knoxville
How long does a flight from Orlando to Knoxville take?
It takes approximately 2 hour to fly non-stop from MCO to TYS, which is 532.36 miles by air.
Which airlines provide the cheapest flights from Orlando (MCO) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from MCO were found on DL : USD 336
Do I need a passport to fly between MCO and TYS?
No
What’s the latest departure time from MCO to TYS ?
The last flight leaves MCO at 10:50 pm

Orlando (MCO) to Knoxville (TYS): Airport Information

Origin Airport Orlando International , Orlando, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 532 miles

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