Cheap flights from Knoxville (TYS) to Worldwide

Good to Know: Cheapest and Fastest Flights from TYS

Useful information for finding cheap flights from McGhee Tyson and booking your next trip

Cheapest Round Trip Flight

$469

American Airlines • 2 stops • 13h 42m

Jul 22 – Aug 05

The cheapest round trip flight from Knoxville to Wichita (TYS-ICT-TYS) is currently $469

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Cheapest One way Flight

$284

United Airlines • 1 stop • 33h 43m

Jul 22

The cheapest one way flight from Knoxville to Quebec (TYS-YQB) is currently $284

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Cheapest Direct Flight

$187

Southwest Airlines • nonstop • 2h 30m

Aug 16

The cheapest nonstop flight from Knoxville to Orlando (TYS-MCO) is currently $187

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Fastest Flight

2h 13m

The fastest nonstop flight from Knoxville to Orlando (TYS-SFB) takes 2h 13m

Top Airlines Flying from McGhee Tyson (TYS)

Southwest Airlines

Delta Airlines

United Airlines

American Airlines

WestJet Airlines

Alaska Airlines

Air Canada

Copa Airlines

Most Recent Flight Deals from Knoxville Now!

Compare and book low fare round-trip air tickets from Knoxville. Ideal for travelers with confirmed return itineraries.

Jul 22 - Aug 05, Economy

Knoxville → Wichita

13h 42m

4:07 PM - 11:29 PM • 2 stops

Knoxville → Wichita

8h 45m

4:53 PM - 11:18 PM • 1 stop

$469

American Airlines

Jul 23 - Aug 06, Economy

Knoxville → Wichita

17h 31m

6:00 AM - 3:51 PM • 2 stops

Knoxville → Wichita

12h 12m

1:45 PM - 10:17 PM • 1 stop

$571

American Airlines

Jul 23 - Aug 06, Economy

Knoxville → Wichita

9h 6m

1:00 PM - 5:46 PM • 1 stop

Knoxville → Wichita

13h 46m

11:33 AM - 8:59 PM • 2 stops

$607

American Airlines

Jul 22 - Aug 05, Economy

Knoxville → Wichita

55h 52m

1:05 PM - 9:57 PM • 3 stops

Knoxville → Wichita

45h 18m

10:48 AM - 3:06 PM • 1 stop

$662

Allegiant

Jul 23 - Aug 06, Economy

Knoxville → Wichita

10h 46m

5:45 PM - 11:31 PM • 1 stop

Knoxville → Wichita

7h 34m

7:25 AM - 1:19 PM • 1 stop

$879

United Airlines

Jul 22 - Aug 05, Economy

Knoxville → Wichita

35h 10m

5:40 PM - 1:50 PM • 1 stop

Knoxville → Wichita

12h 30m

7:40 AM - 4:30 PM • 1 stop

$1019

Southwest Airlines

Explore competitive one-way airfare options from Knoxville. Best suited for flexible or open-ended travel plans.

Jul 22, Economy

Knoxville → Quebec

33h 43m

- • 1 stop

$284

United Airlines

Jul 22, Economy

Knoxville → Quebec

38h 45m

10:00 AM - 9:25 AM • 2 stops

$445

United Airlines

Jul 22, Economy

Knoxville → Quebec

16h 51m

10:00 AM - 9:25 AM • 2 stops

$510

Air Canada

Jul 22, Economy

Knoxville → Quebec

21h 40m

5:40 AM - 6:40 PM • 2 stops

$584

WestJet Airlines

Jul 22, Economy

Knoxville → Quebec

28h 21m

5:45 AM - 10:46 PM • 2 stops

$792

Air Canada

Jul 22, Economy

Knoxville → Quebec

22h 36m

5:45 AM - 7:41 PM • 2 stops

$821

Air Canada

Access real-time availability on last-minute departures from Knoxville. Tailored for urgent or short-notice travel requirements.

Jul 18 - Jul 23, Economy

Knoxville → Portland

15h 45m

2:55 PM - 9:40 PM • 2 stops

Knoxville → Portland

17h 30m

5:20 AM - 7:10 PM • 2 stops

$358

Southwest Airlines

Jul 18 - Jul 23, Economy

Knoxville → Portland

13h 41m

5:31 PM - 10:52 PM • 1 stop

Knoxville → Portland

12h 24m

9:47 PM - 8:31 AM • 1 stop

$389

American Airlines

Jul 18 - Jul 23, Economy

Knoxville → Portland

8h 57m

6:00 AM - 11:37 AM • 1 stop

Knoxville → Portland

18h 40m

11:59 PM - 11:19 AM • 1 stop

$402

United Airlines

Jul 18 - Jul 23, Economy

Knoxville → Portland

18h 55m

2:55 PM - 11:30 PM • 2 stops

Knoxville → Portland

20h 45m

5:30 AM - 9:15 PM • 4 stops

$432

Southwest Airlines

Jul 18 - Jul 23, Economy

Knoxville → Portland

30h 46m

6:45 AM - 10:31 PM • 1 stop

Knoxville → Portland

26h 48m

6:49 PM - 1:57 PM • 1 stop

$1086

Allegiant

Jul 18 - Jul 23, Economy

Knoxville → Portland

40h 51m

3:59 PM - 1:50 PM • 3 stops

Knoxville → Portland

13h 34m

10:45 AM - 9:59 PM • 1 stop

$1835

WestJet Airlines

Discover direct flight options from Knoxville (TYS). Save time by avoiding layovers and reaching your destination directly.

Aug 16 - Aug 21, Economy

Knoxville → Orlando

2h 30m

1:15 PM - 3:05 PM • nonstop

Knoxville → Orlando

2h 25m

3:25 PM - 5:10 PM • nonstop

$187

Southwest Airlines

Jul 14 - Jul 21, Economy

Knoxville → Orlando

2h 15m

4:20 PM - 5:55 PM • nonstop

Knoxville → Orlando

2h 17m

1:53 PM - 3:30 PM • nonstop

$202

Allegiant

Jul 13 - Jul 20, Economy

Knoxville → Orlando

2h 13m

10:05 PM - 11:38 PM • nonstop

Knoxville → Orlando

2h 15m

7:40 PM - 9:15 PM • nonstop

$208

Allegiant

Jul 13 - Jul 20, Economy

Knoxville → Orlando

2h 13m

3:48 PM - 5:21 PM • nonstop

Knoxville → Orlando

2h 15m

7:40 PM - 9:15 PM • nonstop

$334

Allegiant

Jul 16 - Jul 18, Economy

Knoxville → Houston

3h 45m

7:15 AM - 8:40 AM • nonstop

Knoxville → Houston

3h 39m

8:10 AM - 11:29 AM • nonstop

$579

United Airlines

Jul 14 - Jul 21, Economy

Knoxville → Orlando

2h 20m

12:45 PM - 2:25 PM • nonstop

Knoxville → Orlando

2h 30m

3:10 PM - 5:00 PM • nonstop

$790

Southwest Airlines

Affordable Worldwide Flights from McGhee Tyson (TYS)

Looking for cheap last-minute flight deals or the best round-trip flight from Knoxville? Find the biggest savings on one-way and round-trip tickets right here. Search and compare low-cost domestic airfares and international flight deals from TYS to all the popular destinations of the world using our flight search and compare platform. Some top destinations where people fly most from Knoxville are Portland, Las Vegas, Kansas City, Houston, Denver and more.

FAQs on Flights from Knoxville (TYS)

Which airlines fly from Knoxville?

Airlines flying the most from Knoxville (TYS)

What are the most popular destination from Knoxville ( TYS )?

Travelers frequently travel to Quebec, Houston, Wichita, Orlando, Portland, Orlando from Knoxville

Airport Information: McGhee Tyson (TYS)

IATA Code: TYS
Name: McGhee Tyson
City: Knoxville
Country: US
Latitude: 35.81100082397461
Longitude: -83.99400329589844

Knoxville (TYS) Arrivals and Departures

Airline	Flight code	Arrival time	Status
No arrivals found

Airline	Flight code	Departure time	Status
United Airlines UAL47	B772	14th Jul, 2026 4:33 PM	Departed

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Good to Know: Cheapest and Fastest Flights from TYS

Top Airlines Flying from McGhee Tyson (TYS)

Southwest Airlines

Delta Airlines

United Airlines

American Airlines

WestJet Airlines

Alaska Airlines

Air Canada

Copa Airlines

Most Recent Flight Deals from Knoxville Now!

Compare and book low fare round-trip air tickets from Knoxville. Ideal for travelers with confirmed return itineraries.

Explore competitive one-way airfare options from Knoxville. Best suited for flexible or open-ended travel plans.

Access real-time availability on last-minute departures from Knoxville. Tailored for urgent or short-notice travel requirements.

Discover direct flight options from Knoxville (TYS). Save time by avoiding layovers and reaching your destination directly.

Affordable Worldwide Flights from McGhee Tyson (TYS)

FAQs on Flights from Knoxville (TYS)

Airport Information: McGhee Tyson (TYS)

Knoxville (TYS) Arrivals and Departures

More Flight Options from Knoxville, TYS

Trending Flight Routes from Knoxville

Popular Cities to Fly from Knoxville

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