Lowest Prices
We work with hundreds of travel agencies and airlines to bring you the best airfare deals from TYS.
Good to Know: Cheapest and Fastest Flights from TYS
Useful information for finding cheap flights from McGhee Tyson and booking your next trip
Cheapest Round Trip Flight
$334
Allegiant
• 1 stop
• 15h 35m
Jan 07 – Jan 10
The cheapest round trip flight from Knoxville to Tampa (TYS-TPA-TYS) is currently $334
Cheapest One way Flight
$199
American Airlines
• 2 stops
• 12h 37m
Aug 08
The cheapest one way flight from Knoxville to Quebec (TYS-YQB) is currently $199
Cheapest Direct Flight
$177
Allegiant
• nonstop
• 2h 27m
Jan 07
The cheapest nonstop flight from Knoxville to Tampa (TYS-TPA) is currently $177
Fastest Flight
2h 24m
The fastest nonstop flight from Knoxville to Washington (TYS-DCA) takes 2h 24m
Top Airlines Flying from McGhee Tyson (TYS)
Most Recent Flight Deals from Knoxville Now!
Compare and book low fare round-trip air tickets from Knoxville. Ideal for travelers with confirmed return itineraries.
Jan 07 - Jan 10, Economy
Knoxville → Tampa
15h 35m
9:30 PM - 7:05 AM • 1 stop
Knoxville → Tampa
2h 23m
6:33 PM - 8:16 PM • nonstop
Allegiant
Jan 07 - Jan 10, Economy
Knoxville → Tampa
8h 30m
7:00 AM - 12:10 PM • 1 stop
Knoxville → Tampa
15h 10m
8:00 AM - 5:10 PM • 2 stops
Southwest Airlines
Jan 08 - Jan 11, Economy
Knoxville → Tampa
6h 45m
4:00 PM - 8:05 PM • 1 stop
Knoxville → Tampa
5h 41m
8:03 AM - 11:44 AM • 1 stop
American Airlines
Jan 07 - Jan 10, Economy
Knoxville → Tampa
5h 46m
5:30 AM - 9:16 AM • 1 stop
Knoxville → Tampa
7h 33m
1:20 PM - 6:13 PM • 1 stop
Delta Airlines
Jan 08 - Jan 08, Economy
Knoxville → Tampa
8h 26m
7:07 AM - 12:13 PM • 1 stop
Knoxville → Tampa
7h
4:20 PM - 8:40 PM • 1 stop
Delta Airlines
Explore competitive one-way airfare options from Knoxville. Best suited for flexible or open-ended travel plans.
Access real-time availability on last-minute departures from Knoxville. Tailored for urgent or short-notice travel requirements.
Discover direct flight options from Knoxville (TYS). Save time by avoiding layovers and reaching your destination directly.
Jan 07 - Jan 10, Economy
Knoxville → Tampa
2h 27m
9:06 PM - 10:53 PM • nonstop
Knoxville → Tampa
2h 23m
6:33 PM - 8:16 PM • nonstop
Allegiant
Aug 04 - Aug 11, Economy
Knoxville → Washington
4h 4m
12:15 PM - 1:59 PM • nonstop
Knoxville → Washington
48m
7:46 PM - 9:34 PM • nonstop
American Airlines
Jan 08 - Jan 11, Economy
Knoxville → Tampa
2h 27m
9:26 PM - 11:13 PM • nonstop
Knoxville → Tampa
2h 23m
6:53 PM - 8:36 PM • nonstop
Allegiant
Aug 04 - Aug 11, Economy
Knoxville → Washington
2h 25m
1:35 PM - 3:20 PM • nonstop
Knoxville → Washington
2h 28m
7:46 PM - 9:34 PM • nonstop
United Airlines
Aug 04 - Aug 11, Economy
Knoxville → Washington
2h 24m
7:19 PM - 9:03 PM • nonstop
Knoxville → Washington
2h 25m
9:00 AM - 10:45 AM • nonstop
United Airlines
FAQs on Flights from Knoxville (TYS)
Which airlines fly from Knoxville?
Airlines flying the most from Knoxville (TYS)
What are the most popular destination from Knoxville ( TYS )?
Travelers frequently travel to Quebec, Washington, Tampa from Knoxville
Airport Information: McGhee Tyson (TYS)
- IATA Code
- TYS
- Name
- McGhee Tyson
- City
- Knoxville
- Country
- US
- Latitude
- 35.81100082397461
- Longitude
- -83.99400329589844
Knoxville (TYS) Arrivals and Departures
| Airline | Flight code | Arrival time | Status |
|---|---|---|---|
Frontier Airlines
FFT2374
|
A21N
|
3rd Aug, 2026 7:07 PM
|
Arriving |
More Flight Options from Knoxville, TYS
Flights from Knoxville (TYS)
to Sarasota/Bradenton (SRQ)
Flights from Knoxville (TYS)
to Tampa (TPA)
Flights from Knoxville (TYS)
to Jacksonville (JAX)
Flights from Knoxville (TYS)
to Boston (BOS)
Flights from Knoxville (TYS)
to Washington (DCA)
Flights from Knoxville (TYS)
to Buffalo (BUF)
Flights from Knoxville (TYS)
to Las Vegas (LAS)
Flights from Knoxville (TYS)
to Raleigh/Durham (RDU)
Flights from Knoxville (TYS)
to Denver (DEN)
Flights from Knoxville (TYS)
to Seattle (SEA)
Flights from Knoxville (TYS)
to San Jose (SJO)
Flights from Knoxville (TYS)
to Houston (IAH)
Flights from Knoxville (TYS)
to St Louis (STL)
Flights from Knoxville (TYS)
to Chicago (MDW)
Flights from Knoxville (TYS)
to Honolulu (HNL)
Flights from Knoxville (TYS)
to Miami (MIA)
Flights from Knoxville (TYS)
to Omaha (OMA)
Flights from Knoxville (TYS)
to Fort Lauderdale (FLL)
Flights from Knoxville (TYS)
to Detroit (DTW)
Flights from Knoxville (TYS)
to Pensacola (PNS)
Flights from Raleigh/Durham (RDU)
to Knoxville (TYS)
Flights from Montego Bay (MBJ)
to Knoxville (TYS)
Flights from Baltimore (BWI)
to Knoxville (TYS)
Flights from Hartford (BDL)
to Knoxville (TYS)
Flights from New Orleans (MSY)
to Knoxville (TYS)
Flights from Portland (PDX)
to Knoxville (TYS)
Flights from Chicago (MDW)
to Knoxville (TYS)
Flights from Charleston (CHS)
to Knoxville (TYS)
Flights from Seattle (SEA)
to Knoxville (TYS)
Flights from Chicago (ORD)
to Knoxville (TYS)
Flights from Ontario (ONT)
to Knoxville (TYS)
Flights from Ontario (ONT)
to Knoxville (TYS)
Flights from Portland (PWM)
to Knoxville (TYS)
Flights from Minneapolis (MSP)
to Knoxville (TYS)
Flights from Minneapolis (MSP)
to Knoxville (TYS)
Flights from Denver (DEN)
to Knoxville (TYS)
Flights from Detroit (DTW)
to Knoxville (TYS)
Flights from Newark (EWR)
to Knoxville (TYS)
Flights from Boston (BOS)
to Knoxville (TYS)
Flights from Houston (IAH)
to Knoxville (TYS)
Affordable Flight Deals, Everyday
New Deals Everyday
We update prices daily to ensure you never miss the cheapest flight deals from TYS.
No Service Fees
We compare prices to help you find the best TYS airfares, with no service fees.