Cheap Flight Tickets from Pittsburgh (PIT) to Knoxville (TYS), Starting at $447

Good to Know: Cheapest and Fastest PIT - TYS Flights

Useful information for finding best airline tickets from Pittsburgh International to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$447

WN Southwest Airlines • 1 stop • 8h 55m

Jul 28 – Aug 04

The cheapest round trip flight from Pittsburgh to Knoxville (PIT-TYS-PIT) is currently $447

🔍 Search Flights

Fastest Flight

7h 15m

The fastest nonstop flight from Pittsburgh to Knoxville (PIT-TYS) takes 7h 15m

Top Airlines Flying from Pittsburgh to Knoxville

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Pittsburgh (PIT) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Pittsburgh to Knoxville. Ideal for travelers with confirmed return itineraries.

Jul 28 - Aug 04, Economy
WN
Pittsburgh → Knoxville
8h 55m
6:30 AM - 12:05 PM • 1 stop
WN
Pittsburgh → Knoxville
6h 40m
8:05 AM - 12:05 PM • 1 stop
$447
Southwest Airlines
Jul 28 - Aug 04, Economy
WN
Pittsburgh → Knoxville
13h 55m
12:45 PM - 9:20 PM • 1 stop
WN
Pittsburgh → Knoxville
13h 30m
7:00 AM - 3:10 PM • 2 stops
$453
Southwest Airlines
Jul 28 - Aug 04, Economy
WN
Pittsburgh → Knoxville
7h 15m
4:45 PM - 9:20 PM • 1 stop
WN
Pittsburgh → Knoxville
13h 30m
7:00 AM - 3:10 PM • 2 stops
$453
Southwest Airlines
Jul 28 - Aug 04, Economy
WN
Pittsburgh → Knoxville
10h 35m
10:25 AM - 5:00 PM • 1 stop
WN
Pittsburgh → Knoxville
13h 30m
7:00 AM - 3:10 PM • 2 stops
$453
Southwest Airlines
Jul 28 - Aug 04, Economy
WN
Pittsburgh → Knoxville
8h 55m
6:30 AM - 12:05 PM • 1 stop
WN
Pittsburgh → Knoxville
13h 30m
7:00 AM - 3:10 PM • 2 stops
$453
Southwest Airlines
Jul 28 - Aug 04, Economy
WN
Pittsburgh → Knoxville
10h 50m
1:35 PM - 8:25 PM • 1 stop
WN
Pittsburgh → Knoxville
13h 30m
7:00 AM - 3:10 PM • 2 stops
$453
Southwest Airlines

Fly from Pittsburgh to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Pittsburgh to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Pittsburgh to Knoxville Flights

What are the airports in Pittsburgh?
PIT
What’s the most popular airline flying from PIT to TYS?
The most popular airline flying from Pittsburgh to Knoxville are
Can I fly from PIT to TYS non-stop?
NO
Which airlines fly nonstop between Pittsburgh and Knoxville?
The non-stop flights between Pittsburgh and Knoxville are .
What’s the earliest departure time from PIT to TYS Airport?
The earliest flight leaves PIT at 6:30 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Pittsburgh to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from PIT to TYS?
Read the fare rules of the Pittsburgh to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Pittsburgh and Knoxville?
operate flights between Pittsburgh and Knoxville
How long does a flight from Pittsburgh to Knoxville take?
It takes approximately 1 hour to fly non-stop from PIT to TYS, which is 382.24 miles by air.
Which airlines provide the cheapest flights from Pittsburgh (PIT) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from PIT were found on WN : USD 447
Do I need a passport to fly between PIT and TYS?
No
What’s the latest departure time from PIT to TYS ?
The last flight leaves PIT at 4:45 pm

Pittsburgh (PIT) to Knoxville (TYS): Airport Information

Origin Airport Pittsburgh International , Pittsburgh, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 382 miles

More Flight Options for Pittsburgh (PIT) and Knoxville (TYS)

Why Fareleaders for PIT to TYS Plane Tickets

Lowest Prices
Lowest Prices
Uncover the best deals on Pittsburgh to Knoxville flights by comparing fares from hundreds of airlines and agencies.
New Deals
New Deals Everyday
Get the best prices on PIT to TYS flights—we update our fares daily so you never miss a saving.
Best Travel Options
No Service Fees
Compare hundreds of Pittsburgh to Knoxville flights and secure the best deals—we never add any service fees.
Get Fare Drop Alert
Be the first to know when fares drop for the Pittsburgh (PIT) to Knoxville (TYS)
Terms and Conditions*