Lowest Prices
Uncover the best deals on Santa Ana to Knoxville flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest SNA - TYS Flights
Useful information for finding best airline tickets from John Wayne -Orange County to McGhee Tyson on your next trip.
Cheapest Round Trip Flight
$738
Delta Airlines
• 1 stop
• 15h 7m
Aug 20 – Aug 23
The cheapest round trip flight from Santa Ana to Knoxville (SNA-TYS-SNA) is currently $738
Fastest Flight
11h 40m
The fastest nonstop flight from Santa Ana to Knoxville (SNA-TYS) takes 11h 40m
Top Airlines Flying from Santa Ana to Knoxville
Latest Flight Deals from Santa Ana (SNA) to Knoxville (TYS)
Compare and book low fare round-trip air tickets from Santa Ana to Knoxville. Ideal for travelers with confirmed return itineraries.
Aug 20 - Aug 23, Economy
Santa Ana → Knoxville
15h 7m
11:45 AM - 11:52 PM • 1 stop
Santa Ana → Knoxville
10h 44m
6:12 PM - 9:56 PM • 1 stop
Delta Airlines
Aug 20 - Aug 23, Economy
Santa Ana → Knoxville
11h 40m
1:00 PM - 11:00 PM • 1 stop
Santa Ana → Knoxville
10h 44m
6:12 PM - 9:56 PM • 1 stop
Delta Airlines
Aug 20 - Aug 23, Economy
Santa Ana → Knoxville
27h 16m
2:00 PM - 9:36 AM • 1 stop
Santa Ana → Knoxville
13h 38m
4:38 PM - 9:56 PM • 1 stop
Delta Airlines
Aug 20 - Aug 23, Economy
Santa Ana → Knoxville
30h 51m
11:45 AM - 9:36 AM • 1 stop
Santa Ana → Knoxville
13h 38m
4:38 PM - 9:56 PM • 1 stop
Delta Airlines
Aug 20 - Aug 23, Economy
Santa Ana → Knoxville
22h 34m
8:40 PM - 1:34 PM • 2 stops
Santa Ana → Knoxville
10h 44m
6:12 PM - 9:56 PM • 1 stop
Delta Airlines
FAQs on Santa Ana to Knoxville Flights
What are the airports in Santa Ana?
SNA
What’s the most popular airline flying from SNA to TYS?
The most popular airline flying from Santa Ana to Knoxville are
Can I fly from SNA to TYS non-stop?
NO
Which airlines fly nonstop between Santa Ana and Knoxville?
The non-stop flights between Santa Ana and Knoxville are .
What’s the earliest departure time from SNA to TYS Airport?
The earliest flight leaves SNA at 9:52 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Santa Ana to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from SNA to TYS?
Read the fare rules of the Santa Ana to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Santa Ana and Knoxville?
operate flights between Santa Ana and Knoxville
How long does a flight from Santa Ana to Knoxville take?
It takes approximately 4 hour to fly non-stop from SNA to TYS, which is 1923.48 miles by air.
Which airlines provide the cheapest flights from Santa Ana (SNA) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from SNA were found on DL : USD 738
Do I need a passport to fly between SNA and TYS?
No
What’s the latest departure time from SNA to TYS ?
The last flight leaves SNA at 8:40 pm
Santa Ana (SNA) to Knoxville (TYS): Airport Information
| Origin Airport | John Wayne -Orange County , Santa Ana, US |
| Destination Airport | McGhee Tyson , Knoxville, US |
| Distance | 1923 miles |
More Flight Options for Santa Ana (SNA) and Knoxville (TYS)
Flights from Santa Ana (SNA)
to Portland (PDX)
Flights from Santa Ana (SNA)
to Denver (DEN)
Flights from Santa Ana (SNA)
to Las Vegas (LAS)
Flights from Santa Ana (SNA)
to Knoxville (TYS)
Flights from Santa Ana (SNA)
to Pittsburgh (PIT)
Flights from Santa Ana (SNA)
to Seattle (SEA)
Flights from Santa Ana (SNA)
to Austin (AUS)
Flights from Santa Ana (SNA)
to Honolulu (HNL)
Flights from Santa Ana (SNA)
to Buffalo (BUF)
Flights from Santa Ana (SNA)
to Phoenix (PHX)
Flights from Santa Ana (SNA)
to Harrisburg (MDT)
Flights from Santa Ana (SNA)
to Sacramento (SMF)
Flights from Santa Ana (SNA)
to Detroit (DTW)
Flights from Santa Ana (SNA)
to Washington (DCA)
Flights from Santa Ana (SNA)
to Myrtle Beach (MYR)
Flights from Santa Ana (SNA)
to Miami (MIA)
Flights from Santa Ana (SNA)
to Savannah (SAV)
Flights from Santa Ana (SNA)
to Raleigh/Durham (RDU)
Flights from Santa Ana (SNA)
to Chicago (ORD)
Flights from Santa Ana (SNA)
to Fort Lauderdale (FLL)
Flights from Santa Ana (SNA)
to Knoxville (TYS)
Flights from Baltimore (BWI)
to Knoxville (TYS)
Flights from Chicago (ORD)
to Knoxville (TYS)
Flights from Hartford (BDL)
to Knoxville (TYS)
Flights from Houston (IAH)
to Knoxville (TYS)
Flights from Minneapolis (MSP)
to Knoxville (TYS)
Flights from Minneapolis (MSP)
to Knoxville (TYS)
Flights from Portland (PDX)
to Knoxville (TYS)
Flights from Seattle (SEA)
to Knoxville (TYS)
Flights from Montego Bay (MBJ)
to Knoxville (TYS)
Flights from Ontario (ONT)
to Knoxville (TYS)
Flights from Ontario (ONT)
to Knoxville (TYS)
Flights from Chicago (MDW)
to Knoxville (TYS)
Flights from Tampa (TPA)
to Knoxville (TYS)
Flights from Detroit (DTW)
to Knoxville (TYS)
Flights from Orlando (MCO)
to Knoxville (TYS)
Flights from Denver (DEN)
to Knoxville (TYS)
Flights from Portland (PWM)
to Knoxville (TYS)
Flights from Boston (BOS)
to Knoxville (TYS)
Flights from Dallas (DFW)
to Knoxville (TYS)
Cheap flights to North America (NA)
Cheap flights to United States (US)
Cheap flights to Tennessee (US-TN)
Cheap flights to California (US-CA)
Cheap flights from North America (NA)
Cheap flights from United States (US)
Cheap flights from California (US-CA)
Cheap flights from Tennessee (US-TN)
Flights to Santa Ana (SNA)
Flights to Knoxville (TYS)
Flights from Santa Ana (SNA)
Flights from Knoxville (TYS)
Flights from Knoxville (TYS)
to Santa Ana (SNA)
Why Fareleaders for SNA to TYS Plane Tickets
New Deals Everyday
Get the best prices on SNA to TYS flights—we update our fares daily so you never miss a saving.
No Service Fees
Compare hundreds of Santa Ana to Knoxville flights and secure the best deals—we never add any service fees.