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Good to Know: Cheapest and Fastest TPA - TYS Flights
Useful information for finding best airline tickets from Tampa International to McGhee Tyson on your next trip.
Cheapest Round Trip Flight
$350
Allegiant
• nonstop
• 2h 18m
Oct 08 – Oct 13
The cheapest round trip flight from Tampa to Knoxville (TPA-TYS-TPA) is currently $350
Cheapest Direct Flight
$63
Allegiant
• nonstop
• 2h 19m
Sep 14
The cheapest nonstop flight from Tampa to Knoxville (TPA-TYS) is currently $63
Fastest Flight
2h 18m
The fastest nonstop flight from Tampa to Knoxville (TPA-TYS) takes 2h 18m
Top Airlines Flying from Tampa to Knoxville
Latest Flight Deals from Tampa (TPA) to Knoxville (TYS)
Compare and book low fare round-trip air tickets from Tampa to Knoxville. Ideal for travelers with confirmed return itineraries.
Oct 08 - Oct 13, Economy
Tampa → Knoxville
2h 18m
7:00 PM - 8:38 PM • nonstop
Tampa → Knoxville
2h 19m
4:04 PM - 5:43 PM • nonstop
Allegiant
Oct 07 - Oct 12, Economy
Tampa → Knoxville
40h 19m
12:52 PM - 1:11 PM • 2 stops
Tampa → Knoxville
2h 19m
9:25 PM - 11:04 PM • nonstop
Frontier Airlines
Oct 07 - Oct 12, Economy
Tampa → Knoxville
7h 15m
11:25 AM - 9:05 PM • 2 stops
Tampa → Knoxville
9h 5m
1:50 PM - 11:35 PM • 2 stops
Southwest Airlines
Oct 07 - Oct 12, Economy
Tampa → Knoxville
13h 27m
7:05 AM - 3:12 PM • 2 stops
Tampa → Knoxville
10h 57m
6:56 AM - 1:53 PM • 2 stops
American Airlines
Oct 08 - Oct 13, Economy
Tampa → Knoxville
3h 49m
10:00 AM - 1:40 PM • 1 stop
Tampa → Knoxville
3h 58m
7:09 AM - 12:44 PM • 1 stop
Delta Airlines
Flying to Knoxville soon? We've surfaced some of the most affordable last-minute flights from Tampa to Knoxville, ideal for urgent plans or spontaneous trips.
Sep 14 - Sep 16, Economy
Tampa → Knoxville
7h 6m
1:05 PM - 5:31 PM • 1 stop
Tampa → Knoxville
5h 57m
6:15 AM - 10:12 AM • 1 stop
American Airlines
Sep 14 - Sep 16, Economy
Tampa → Knoxville
6h 40m
5:44 AM - 9:44 AM • 1 stop
Tampa → Knoxville
8h 33m
12:09 PM - 5:22 PM • 1 stop
American Airlines
Sep 14 - Sep 16, Economy
Tampa → Knoxville
5h 35m
4:40 PM - 8:15 PM • 1 stop
Tampa → Knoxville
5h 14m
5:40 AM - 8:54 AM • 1 stop
Delta Airlines
Sep 14 - Sep 16, Economy
Tampa → Knoxville
5h 56m
7:59 PM - 11:55 PM • 1 stop
Tampa → Knoxville
5h 7m
12:23 PM - 3:30 PM • 1 stop
Delta Airlines
Sep 14 - Sep 16, Economy
Tampa → Knoxville
5h 21m
10:00 AM - 1:21 PM • 1 stop
Tampa → Knoxville
5h 7m
12:23 PM - 3:30 PM • 1 stop
Delta Airlines
Looking for the fastest way to Knoxville? These direct flight options from TPA to TYS offer both convenience and value—no layovers, just straight to your destination.
Sep 14 - Sep 16, Economy
Tampa → Knoxville
2h 19m
9:35 AM - 11:14 AM • nonstop
Tampa → Knoxville
2h 22m
5:18 PM - 7:00 PM • nonstop
Allegiant
Sep 13 - Sep 16, Economy
Tampa → Knoxville
2h 19m
9:05 AM - 10:44 AM • nonstop
Tampa → Knoxville
2h 22m
5:18 PM - 7:00 PM • nonstop
Allegiant
Sep 14 - Sep 16, Economy
Tampa → Knoxville
2h 19m
4:35 PM - 6:14 PM • nonstop
Tampa → Knoxville
2h 22m
5:18 PM - 7:00 PM • nonstop
Allegiant
Oct 07 - Oct 12, Economy
Tampa → Knoxville
2h 18m
8:00 AM - 9:38 AM • nonstop
Tampa → Knoxville
2h 19m
9:25 PM - 11:04 PM • nonstop
Allegiant
Oct 08 - Oct 13, Economy
Tampa → Knoxville
2h 18m
6:15 AM - 7:53 AM • nonstop
Tampa → Knoxville
2h 19m
4:04 PM - 5:43 PM • nonstop
Allegiant
FAQs on Tampa to Knoxville Flights
What are the airports in Tampa?
TPA
What’s the most popular airline flying from TPA to TYS?
The most popular airline flying from Tampa to Knoxville are
Can I fly from TPA to TYS non-stop?
Yes, you can fly TPA to TYS non-stop on
Which airlines fly nonstop between Tampa and Knoxville?
The non-stop flights between Tampa and Knoxville are .
What’s the earliest departure time from TPA to TYS Airport?
The earliest flight leaves TPA at 5:44 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Tampa to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TPA to TYS?
Read the fare rules of the Tampa to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Tampa and Knoxville?
operate flights between Tampa and Knoxville
How long does a flight from Tampa to Knoxville take?
It takes approximately 2 hour to fly non-stop from TPA to TYS, which is 546.64 miles by air.
Which airlines provide the cheapest flights from Tampa (TPA) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from TPA were found on AA : USD 654
Do I need a passport to fly between TPA and TYS?
No
What’s the latest departure time from TPA to TYS ?
The last flight leaves TPA at 7:59 pm
Tampa (TPA) to Knoxville (TYS): Airport Information
| Origin Airport | Tampa International , Tampa, US |
| Destination Airport | McGhee Tyson , Knoxville, US |
| Distance | 547 miles |
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