Cheap Flight Tickets from Columbus (CMH) to Knoxville (TYS), Starting at $378

Good to Know: Cheapest and Fastest CMH - TYS Flights

Useful information for finding best airline tickets from Port Columbus International to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$378

AA American Airlines • 1 stop • 7h 22m

Aug 25 – Aug 26

The cheapest round trip flight from Columbus to Knoxville (CMH-TYS-CMH) is currently $378

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Fastest Flight

5h 32m

The fastest nonstop flight from Columbus to Knoxville (CMH-TYS) takes 5h 32m

Top Airlines Flying from Columbus to Knoxville

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

WestJet Airlines

WestJet Airlines

Latest Flight Deals from Columbus (CMH) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Columbus to Knoxville. Ideal for travelers with confirmed return itineraries.

Aug 25 - Aug 26, Economy
AA
Columbus → Knoxville
7h 22m
4:17 PM - 8:59 PM • 1 stop
AA
Columbus → Knoxville
5h 30m
7:25 PM - 10:55 PM • 1 stop
$378
American Airlines
Aug 25 - Aug 26, Economy
DL
Columbus → Knoxville
5h 32m
10:02 AM - 1:34 PM • 1 stop
DL
Columbus → Knoxville
6h 48m
7:30 AM - 11:38 AM • 1 stop
$378
Delta Airlines
Aug 25 - Aug 26, Economy
DL
Columbus → Knoxville
5h 57m
2:59 PM - 6:56 PM • 1 stop
DL
Columbus → Knoxville
5h 50m
5:22 PM - 9:12 PM • 1 stop
$378
Delta Airlines
Aug 26 - Aug 26, Economy
UA
Columbus → Knoxville
7h 17m
5:20 AM - 9:57 AM • 1 stop
UA
Columbus → Knoxville
10h
1:00 PM - 7:00 PM • 1 stop
$681
United Airlines
Aug 25 - Aug 25, Economy
WN
Columbus → Knoxville
10h 40m
6:25 AM - 1:05 PM • 1 stop
WN
Columbus → Knoxville
5h 40m
5:30 PM - 9:10 PM • 1 stop
$686
Southwest Airlines
Aug 25 - Aug 26, Economy
WN
Columbus → Knoxville
7h 15m
3:15 PM - 7:50 PM • 1 stop
WN
Columbus → Knoxville
7h
8:05 AM - 12:25 PM • 1 stop
$686
Southwest Airlines

Fly from Columbus to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Columbus to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Columbus to Knoxville Flights

What are the airports in Columbus?
CMH
What’s the most popular airline flying from CMH to TYS?
The most popular airline flying from Columbus to Knoxville are
Can I fly from CMH to TYS non-stop?
NO
Which airlines fly nonstop between Columbus and Knoxville?
The non-stop flights between Columbus and Knoxville are .
What’s the earliest departure time from CMH to TYS Airport?
The earliest flight leaves CMH at 5:20 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Columbus to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from CMH to TYS?
Read the fare rules of the Columbus to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Columbus and Knoxville?
operate flights between Columbus and Knoxville
How long does a flight from Columbus to Knoxville take?
It takes approximately 1 hour to fly non-stop from CMH to TYS, which is 294.98 miles by air.
Which airlines provide the cheapest flights from Columbus (CMH) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from CMH were found on AA : USD 378
Do I need a passport to fly between CMH and TYS?
No
What’s the latest departure time from CMH to TYS ?
The last flight leaves CMH at 4:17 pm

Columbus (CMH) to Knoxville (TYS): Airport Information

Origin Airport Port Columbus International , Columbus, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 295 miles

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