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Good to Know: Cheapest and Fastest BUF - TYS Flights
Useful information for finding best airline tickets from Buffalo Niagara International to McGhee Tyson on your next trip.
Cheapest Round Trip Flight
$166
Southwest Airlines
• 1 stop
• 7h 35m
Sep 16 – Sep 21
The cheapest round trip flight from Buffalo to Knoxville (BUF-TYS-BUF) is currently $166
Fastest Flight
7h 25m
The fastest nonstop flight from Buffalo to Knoxville (BUF-TYS) takes 7h 25m
Top Airlines Flying from Buffalo to Knoxville
Latest Flight Deals from Buffalo (BUF) to Knoxville (TYS)
Compare and book low fare round-trip air tickets from Buffalo to Knoxville. Ideal for travelers with confirmed return itineraries.
Sep 16 - Sep 21, Economy
Buffalo → Knoxville
7h 35m
3:00 PM - 7:55 PM • 1 stop
Buffalo → Knoxville
16h 40m
8:25 AM - 6:25 PM • 1 stop
Southwest Airlines
Sep 16 - Sep 21, Economy
Buffalo → Knoxville
16h 45m
8:55 AM - 7:00 PM • 2 stops
Buffalo → Knoxville
15h 40m
7:10 AM - 4:50 PM • 1 stop
Southwest Airlines
Sep 16 - Sep 21, Economy
Buffalo → Knoxville
10h 54m
2:10 PM - 9:04 PM • 1 stop
Buffalo → Knoxville
10h 25m
5:28 PM - 11:53 PM • 1 stop
Delta Airlines
Sep 16 - Sep 21, Economy
Buffalo → Knoxville
8h 33m
6:05 AM - 11:18 AM • 1 stop
Buffalo → Knoxville
10h 25m
5:28 PM - 11:53 PM • 1 stop
Delta Airlines
Sep 13 - Sep 20, Economy
Buffalo → Knoxville
12h 35m
12:55 PM - 8:50 PM • 1 stop
Buffalo → Knoxville
18h 35m
1:15 PM - 12:30 AM • 1 stop
Southwest Airlines
Flying to Knoxville soon? We've surfaced some of the most affordable last-minute flights from Buffalo to Knoxville, ideal for urgent plans or spontaneous trips.
Sep 13 - Sep 20, Economy
Buffalo → Knoxville
12h 35m
12:55 PM - 8:50 PM • 1 stop
Buffalo → Knoxville
18h 35m
1:15 PM - 12:30 AM • 1 stop
Southwest Airlines
Sep 13 - Sep 20, Economy
Buffalo → Knoxville
13h 50m
12:20 PM - 8:50 PM • 2 stops
Buffalo → Knoxville
17h 25m
7:35 AM - 6:20 PM • 1 stop
Southwest Airlines
Sep 13 - Sep 20, Economy
Buffalo → Knoxville
22h 30m
8:00 AM - 9:50 PM • 2 stops
Buffalo → Knoxville
5h 45m
8:30 AM - 12:15 PM • 1 stop
Southwest Airlines
Sep 13 - Sep 20, Economy
Buffalo → Knoxville
15h 20m
11:30 AM - 8:50 PM • 2 stops
Buffalo → Knoxville
15h 40m
1:15 PM - 10:55 PM • 2 stops
Southwest Airlines
Sep 13 - Sep 20, Economy
Buffalo → Knoxville
7h 25m
11:31 AM - 4:16 PM • 1 stop
Buffalo → Knoxville
10h 12m
6:30 AM - 12:42 PM • 1 stop
American Airlines
FAQs on Buffalo to Knoxville Flights
What are the airports in Buffalo?
BUF
What’s the most popular airline flying from BUF to TYS?
The most popular airline flying from Buffalo to Knoxville are
Can I fly from BUF to TYS non-stop?
NO
Which airlines fly nonstop between Buffalo and Knoxville?
The non-stop flights between Buffalo and Knoxville are .
What’s the earliest departure time from BUF to TYS Airport?
The earliest flight leaves BUF at 6:05 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Buffalo to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from BUF to TYS?
Read the fare rules of the Buffalo to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Buffalo and Knoxville?
operate flights between Buffalo and Knoxville
How long does a flight from Buffalo to Knoxville take?
It takes approximately 2 hour to fly non-stop from BUF to TYS, which is 566.52 miles by air.
Which airlines provide the cheapest flights from Buffalo (BUF) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from BUF were found on DL : USD 210
Do I need a passport to fly between BUF and TYS?
No
What’s the latest departure time from BUF to TYS ?
The last flight leaves BUF at 3:42 pm
Buffalo (BUF) to Knoxville (TYS): Airport Information
| Origin Airport | Buffalo Niagara International , Buffalo, US |
| Destination Airport | McGhee Tyson , Knoxville, US |
| Distance | 567 miles |
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