Cheap Flight Tickets from Buffalo (BUF) to Knoxville (TYS), Starting at $580

Good to Know: Cheapest and Fastest BUF - TYS Flights

Useful information for finding best airline tickets from Buffalo Niagara International to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$580

DL Delta Airlines • 1 stop • 5h 58m

Jul 01 – Jul 04

The cheapest round trip flight from Buffalo to Knoxville (BUF-TYS-BUF) is currently $580

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Fastest Flight

5h 58m

The fastest nonstop flight from Buffalo to Knoxville (BUF-TYS) takes 5h 58m

Top Airlines Flying from Buffalo to Knoxville

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Buffalo (BUF) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Buffalo to Knoxville. Ideal for travelers with confirmed return itineraries.

Jul 01 - Jul 04, Economy
DL
Buffalo → Knoxville
5h 58m
6:29 AM - 10:27 AM • 1 stop
DL
Buffalo → Knoxville
5h 49m
11:32 AM - 3:21 PM • 1 stop
$580
Delta Airlines
Jul 01 - Jul 04, Economy
AA
Buffalo → Knoxville
8h 42m
2:47 PM - 8:09 PM • 1 stop
AA
Buffalo → Knoxville
5h 54m
8:56 AM - 12:50 PM • 1 stop
$786
American Airlines
Jul 01 - Jul 04, Economy
AA
Buffalo → Knoxville
6h 50m
6:26 AM - 10:36 AM • 1 stop
AA
Buffalo → Knoxville
5h 54m
8:56 AM - 12:50 PM • 1 stop
$786
American Airlines
Jul 01 - Jul 04, Economy
DL
Buffalo → Knoxville
9h 18m
12:04 PM - 6:02 PM • 1 stop
DL
Buffalo → Knoxville
5h 49m
11:32 AM - 3:21 PM • 1 stop
$803
Delta Airlines
Jul 01 - Jul 04, Economy
UA
Buffalo → Knoxville
10h 3m
10:57 AM - 5:00 PM • 1 stop
UA
Buffalo → Knoxville
6h 46m
5:45 AM - 9:51 AM • 1 stop
$881
United Airlines
Jul 01 - Jul 04, Economy
DL
Buffalo → Knoxville
7h 24m
6:03 AM - 10:47 AM • 1 stop
DL
Buffalo → Knoxville
5h 49m
11:32 AM - 3:21 PM • 1 stop
$896
Delta Airlines

Fly from Buffalo to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Buffalo to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Buffalo to Knoxville Flights

What are the airports in Buffalo?
BUF
What’s the most popular airline flying from BUF to TYS?
The most popular airline flying from Buffalo to Knoxville are
Can I fly from BUF to TYS non-stop?
NO
Which airlines fly nonstop between Buffalo and Knoxville?
The non-stop flights between Buffalo and Knoxville are .
What’s the earliest departure time from BUF to TYS Airport?
The earliest flight leaves BUF at 6:03 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Buffalo to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from BUF to TYS?
Read the fare rules of the Buffalo to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Buffalo and Knoxville?
operate flights between Buffalo and Knoxville
How long does a flight from Buffalo to Knoxville take?
It takes approximately 2 hour to fly non-stop from BUF to TYS, which is 566.52 miles by air.
Which airlines provide the cheapest flights from Buffalo (BUF) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from BUF were found on DL : USD 803
Do I need a passport to fly between BUF and TYS?
No
What’s the latest departure time from BUF to TYS ?
The last flight leaves BUF at 2:47 pm

Buffalo (BUF) to Knoxville (TYS): Airport Information

Origin Airport Buffalo Niagara International , Buffalo, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 567 miles

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