Cheap Flight Tickets from Chicago (ORD) to Knoxville (TYS), Starting at $221

Good to Know: Cheapest and Fastest ORD - TYS Flights

Useful information for finding best airline tickets from Chicago O'Hare International to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$221

F9 Frontier Airlines • 1 stop • 9h 10m

Jul 19 – Jul 24

The cheapest round trip flight from Chicago to Knoxville (ORD-TYS-ORD) is currently $221

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Cheapest One way Flight

$489

WN Southwest Airlines • 1 stop • 30h 20m

Jul 26

The cheapest one way flight from Chicago to Knoxville (ORD-TYS) is currently $489

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Cheapest Direct Flight

$474

AA American Airlines • nonstop • 2h 29m

Jul 19

The cheapest nonstop flight from Chicago to Knoxville (ORD-TYS) is currently $474

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Fastest Flight

2h 28m

The fastest nonstop flight from Chicago to Knoxville (ORD-TYS) takes 2h 28m

Latest Flight Deals from Chicago (ORD) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Chicago to Knoxville. Ideal for travelers with confirmed return itineraries.

Jul 19 - Jul 24, Economy
F9
Chicago → Knoxville
9h 10m
9:57 PM - 7:24 PM • 1 stop
F9
Chicago → Knoxville
10h 10m
8:19 PM - 8:52 PM • 1 stop
$221
Frontier Airlines
Jul 19 - Jul 24, Economy
AA
Chicago → Knoxville
2h 29m
2:59 PM - 5:48 PM • nonstop
AA
Chicago → Knoxville
2h 39m
1:00 PM - 1:59 PM • nonstop
$474
American Airlines
Jul 19 - Jul 24, Economy
AA
Chicago → Knoxville
2h 30m
8:15 AM - 11:05 AM • nonstop
AA
Chicago → Knoxville
2h 39m
1:00 PM - 1:59 PM • nonstop
$474
American Airlines
Jul 19 - Jul 24, Economy
UA
Chicago → Knoxville
2h 29m
5:59 PM - 8:48 PM • nonstop
UA
Chicago → Knoxville
3h 21m
1:54 PM - 2:55 PM • nonstop
$474
United Airlines
Jul 19 - Jul 24, Economy
UA
Chicago → Knoxville
2h 28m
6:55 AM - 9:43 AM • nonstop
UA
Chicago → Knoxville
3h 21m
1:54 PM - 2:55 PM • nonstop
$474
United Airlines
Jul 19 - Jul 24, Economy
AA
Chicago → Knoxville
2h 29m
7:15 PM - 10:04 PM • nonstop
AA
Chicago → Knoxville
2h 39m
1:00 PM - 1:59 PM • nonstop
$474
American Airlines

Fly from Chicago to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Chicago to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Chicago to Knoxville Flights

What are the airports in Chicago?
MDW,ORD
What’s the most popular airline flying from ORD to TYS?
The most popular airline flying from Chicago to Knoxville are
Can I fly from ORD to TYS non-stop?
Yes, you can fly ORD to TYS non-stop on
Which airlines fly nonstop between Chicago and Knoxville?
The non-stop flights between Chicago and Knoxville are .
What’s the earliest departure time from ORD to TYS Airport?
The earliest flight leaves ORD at 6:55 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Chicago to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from ORD to TYS?
Read the fare rules of the Chicago to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Chicago and Knoxville?
operate flights between Chicago and Knoxville
How long does a flight from Chicago to Knoxville take?
It takes approximately 2 hour to fly non-stop from ORD to TYS, which is 474.67 miles by air.
Which airlines provide the cheapest flights from Chicago (ORD) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from ORD were found on WN : USD 489
Do I need a passport to fly between ORD and TYS?
No
What’s the latest departure time from ORD to TYS ?
The last flight leaves ORD at 9:57 pm

Chicago (ORD) to Knoxville (TYS): Airport Information

Origin Airport Chicago O'Hare International , Chicago, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 475 miles

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