Cheap Flight Tickets from Chicago (ORD) to Knoxville (TYS), Starting at $277

Good to Know: Cheapest and Fastest ORD - TYS Flights

Useful information for finding best airline tickets from Chicago O'Hare International to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$438

DL Delta Airlines • 1 stop • 7h 4m

Oct 07 – Oct 11

The cheapest round trip flight from Chicago to Knoxville (ORD-TYS-ORD) is currently $438

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Cheapest Direct Flight

$494

UA United Airlines • nonstop • 2h 28m

Sep 17

The cheapest nonstop flight from Chicago to Knoxville (ORD-TYS) is currently $494

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Fastest Flight

2h 27m

The fastest nonstop flight from Chicago to Knoxville (ORD-TYS) takes 2h 27m

Top Airlines Flying from Chicago to Knoxville

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Chicago (ORD) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Chicago to Knoxville. Ideal for travelers with confirmed return itineraries.

Oct 07 - Oct 11, Economy
DL
Chicago → Knoxville
7h 4m
1:23 PM - 6:47 PM • 1 stop
DL
Chicago → Knoxville
5h 59m
5:40 AM - 8:39 AM • 1 stop
$438
Delta Airlines
Oct 07 - Oct 11, Economy
DL
Chicago → Knoxville
7h 7m
5:27 AM - 10:54 AM • 1 stop
DL
Chicago → Knoxville
5h 42m
9:12 AM - 11:54 AM • 1 stop
$438
Delta Airlines
Oct 07 - Oct 11, Economy
DL
Chicago → Knoxville
5h 42m
10:44 AM - 3:26 PM • 1 stop
DL
Chicago → Knoxville
5h 42m
9:12 AM - 11:54 AM • 1 stop
$438
Delta Airlines
Oct 07 - Oct 11, Economy
DL
Chicago → Knoxville
7h 15m
8:05 AM - 1:40 PM • 1 stop
DL
Chicago → Knoxville
6h 41m
9:12 AM - 12:13 PM • 1 stop
$438
Delta Airlines
Sep 17 - Sep 19, Economy
UA
Chicago → Knoxville
2h 28m
2:10 PM - 4:58 PM • nonstop
UA
Chicago → Knoxville
3h 24m
10:45 AM - 11:49 AM • nonstop
$494
United Airlines
Sep 17 - Sep 19, Economy
DL
Chicago → Knoxville
5h 49m
1:51 PM - 6:40 PM • 1 stop
DL
Chicago → Knoxville
6h 46m
1:31 PM - 4:37 PM • 1 stop
$583
Delta Airlines

Fly from Chicago to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Chicago to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Chicago to Knoxville Flights

What are the airports in Chicago?
MDW,ORD
What’s the most popular airline flying from ORD to TYS?
The most popular airline flying from Chicago to Knoxville are
Can I fly from ORD to TYS non-stop?
Yes, you can fly ORD to TYS non-stop on
Which airlines fly nonstop between Chicago and Knoxville?
The non-stop flights between Chicago and Knoxville are .
What’s the earliest departure time from ORD to TYS Airport?
The earliest flight leaves ORD at 5:20 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Chicago to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from ORD to TYS?
Read the fare rules of the Chicago to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Chicago and Knoxville?
operate flights between Chicago and Knoxville
How long does a flight from Chicago to Knoxville take?
It takes approximately 2 hour to fly non-stop from ORD to TYS, which is 474.67 miles by air.
Which airlines provide the cheapest flights from Chicago (ORD) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from ORD were found on DL : USD 438
Do I need a passport to fly between ORD and TYS?
No
What’s the latest departure time from ORD to TYS ?
The last flight leaves ORD at 8:02 pm

Chicago (ORD) to Knoxville (TYS): Airport Information

Origin Airport Chicago O'Hare International , Chicago, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 475 miles

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