Cheap Flight Tickets from Houston (HOU) to Knoxville (TYS), Starting at $315

Good to Know: Cheapest and Fastest HOU - TYS Flights

Useful information for finding best airline tickets from William P Hobby to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$315

WN Southwest Airlines • 1 stop • 8h 55m

Dec 25 – Dec 28

The cheapest round trip flight from Houston to Knoxville (HOU-TYS-HOU) is currently $315

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Fastest Flight

5h 45m

The fastest nonstop flight from Houston to Knoxville (HOU-TYS) takes 5h 45m

Top Airlines Flying from Houston to Knoxville

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

Latest Flight Deals from Houston (HOU) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Houston to Knoxville. Ideal for travelers with confirmed return itineraries.

Dec 25 - Dec 28, Economy
WN
Houston → Knoxville
8h 55m
7:30 AM - 2:05 PM • 1 stop
WN
Houston → Knoxville
13h 40m
12:40 PM - 8:00 PM • 1 stop
$315
Southwest Airlines
Dec 25 - Dec 28, Economy
WN
Houston → Knoxville
8h 45m
1:20 PM - 7:45 PM • 1 stop
WN
Houston → Knoxville
13h 50m
3:45 PM - 11:15 PM • 1 stop
$315
Southwest Airlines
Dec 25 - Dec 28, Economy
WN
Houston → Knoxville
5h 45m
7:35 AM - 12:20 PM • 1 stop
WN
Houston → Knoxville
20h 25m
7:15 PM - 6:40 AM • 2 stops
$347
Southwest Airlines
Dec 25 - Dec 28, Economy
WN
Houston → Knoxville
13h 45m
7:15 AM - 4:40 PM • 2 stops
WN
Houston → Knoxville
5h 55m
7:15 PM - 10:10 PM • 1 stop
$387
Southwest Airlines
Dec 25 - Dec 28, Economy
WN
Houston → Knoxville
13h 35m
11:30 AM - 8:45 PM • 2 stops
WN
Houston → Knoxville
5h 55m
7:15 PM - 10:10 PM • 1 stop
$387
Southwest Airlines
Dec 25 - Dec 28, Economy
WN
Houston → Knoxville
8h 45m
1:20 PM - 7:45 PM • 1 stop
WN
Houston → Knoxville
13h 25m
12:40 PM - 7:45 PM • 2 stops
$408
Southwest Airlines

Fly from Houston to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Houston to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Houston to Knoxville Flights

What are the airports in Houston?
HOU
What’s the most popular airline flying from HOU to TYS?
The most popular airline flying from Houston to Knoxville are
Can I fly from HOU to TYS non-stop?
NO
Which airlines fly nonstop between Houston and Knoxville?
The non-stop flights between Houston and Knoxville are .
What’s the earliest departure time from HOU to TYS Airport?
The earliest flight leaves HOU at 7:15 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Houston to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from HOU to TYS?
Read the fare rules of the Houston to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Houston and Knoxville?
operate flights between Houston and Knoxville
How long does a flight from Houston to Knoxville take?
It takes approximately 2 hour to fly non-stop from HOU to TYS, which is 781.81 miles by air.
Which airlines provide the cheapest flights from Houston (HOU) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from HOU were found on WN : USD 347
Do I need a passport to fly between HOU and TYS?
No
What’s the latest departure time from HOU to TYS ?
The last flight leaves HOU at 1:20 pm

Houston (HOU) to Knoxville (TYS): Airport Information

Origin Airport William P Hobby , Houston, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 782 miles

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