Cheap Flight Tickets from Houston (HOU) to Knoxville (TYS), Starting at $233

Good to Know: Cheapest and Fastest HOU - TYS Flights

Useful information for finding best airline tickets from William P Hobby to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$287

WN Southwest Airlines • 2 stops • 20h 15m

Jul 16 – Jul 19

The cheapest round trip flight from Houston to Knoxville (HOU-TYS-HOU) is currently $287

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Cheapest Direct Flight

$233

UA United Airlines • nonstop • 3h 42m

Jul 17

The cheapest nonstop flight from Houston to Knoxville (HOU-TYS) is currently $233

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Fastest Flight

3h 39m

The fastest nonstop flight from Houston to Knoxville (HOU-TYS) takes 3h 39m

Top Airlines Flying from Houston to Knoxville

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Houston (HOU) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Houston to Knoxville. Ideal for travelers with confirmed return itineraries.

Jul 16 - Jul 19, Economy
WN
Houston → Knoxville
20h 15m
10:45 PM - 12:00 PM • 2 stops
WN
Houston → Knoxville
24h 10m
8:00 AM - 9:50 PM • 4 stops
$287
Southwest Airlines
Jul 16 - Jul 19, Economy
WN
Houston → Knoxville
20h 25m
7:50 AM - 9:15 PM • 2 stops
WN
Houston → Knoxville
13h 30m
12:45 PM - 7:55 PM • 2 stops
$292
Southwest Airlines
Jul 17 - Jul 20, Economy
WN
Houston → Knoxville
15h 55m
8:15 AM - 7:10 PM • 1 stop
WN
Houston → Knoxville
10h 5m
7:45 PM - 12:50 AM • 1 stop
$458
Southwest Airlines
Jul 17 - Jul 20, Economy
WN
Houston → Knoxville
20h 40m
5:30 AM - 7:10 PM • 1 stop
WN
Houston → Knoxville
20h 40m
7:45 PM - 7:25 AM • 2 stops
$464
Southwest Airlines
Jul 17 - Jul 20, Economy
WN
Houston → Knoxville
20h 55m
7:20 AM - 9:15 PM • 2 stops
WN
Houston → Knoxville
20h 45m
7:45 PM - 7:30 AM • 2 stops
$469
Southwest Airlines
Jul 17 - Jul 20, Economy
WN
Houston → Knoxville
10h 45m
1:30 PM - 9:15 PM • 2 stops
WN
Houston → Knoxville
10h 5m
7:45 PM - 12:50 AM • 1 stop
$499
Southwest Airlines

Fly from Houston to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Houston to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Houston to Knoxville Flights

What are the airports in Houston?
HOU
What’s the most popular airline flying from HOU to TYS?
The most popular airline flying from Houston to Knoxville are
Can I fly from HOU to TYS non-stop?
Yes, you can fly HOU to TYS non-stop on
Which airlines fly nonstop between Houston and Knoxville?
The non-stop flights between Houston and Knoxville are .
What’s the earliest departure time from HOU to TYS Airport?
The earliest flight leaves HOU at 5:30 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Houston to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from HOU to TYS?
Read the fare rules of the Houston to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Houston and Knoxville?
operate flights between Houston and Knoxville
How long does a flight from Houston to Knoxville take?
It takes approximately 2 hour to fly non-stop from HOU to TYS, which is 781.81 miles by air.
Which airlines provide the cheapest flights from Houston (HOU) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from HOU were found on WN : USD 287
Do I need a passport to fly between HOU and TYS?
No
What’s the latest departure time from HOU to TYS ?
The last flight leaves HOU at 10:45 pm

Houston (HOU) to Knoxville (TYS): Airport Information

Origin Airport William P Hobby , Houston, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 782 miles

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