Cheap Flight Tickets from Houston (HOU) to Knoxville (TYS), Starting at $197

Good to Know: Cheapest and Fastest HOU - TYS Flights

Useful information for finding best airline tickets from William P Hobby to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$197

AA American Airlines • 1 stop • 8h 52m

Jul 01 – Jul 05

The cheapest round trip flight from Houston to Knoxville (HOU-TYS-HOU) is currently $197

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Cheapest Direct Flight

$213

UA United Airlines • nonstop • 3h 39m

Jul 01

The cheapest nonstop flight from Houston to Knoxville (HOU-TYS) is currently $213

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Fastest Flight

3h 39m

The fastest nonstop flight from Houston to Knoxville (HOU-TYS) takes 3h 39m

Top Airlines Flying from Houston to Knoxville

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Houston (HOU) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Houston to Knoxville. Ideal for travelers with confirmed return itineraries.

Jul 01 - Jul 05, Economy
AA
Houston → Knoxville
8h 52m
6:03 AM - 12:35 PM • 1 stop
AA
Houston → Knoxville
8h 31m
5:37 AM - 9:48 AM • 1 stop
$197
American Airlines
Jul 01 - Jul 05, Economy
WN
Houston → Knoxville
18h 20m
5:00 AM - 5:00 PM • 1 stop
WN
Houston → Knoxville
15h 45m
7:05 AM - 3:50 PM • 1 stop
$271
Southwest Airlines
Jul 01 - Jul 05, Economy
DL
Houston → Knoxville
6h 54m
5:40 AM - 1:19 PM • 1 stop
DL
Houston → Knoxville
10h 40m
3:54 PM - 9:34 PM • 1 stop
$314
Delta Airlines
Jul 02 - Jul 06, Economy
B6
Houston → Knoxville
27h 10m
6:20 PM - 11:50 AM • 1 stop
G4
Houston → Knoxville
42h 14m
10:05 PM - 10:39 PM • 2 stops
$830
JetBlue Airways
Jul 02 - Jul 06, Economy
UA
Houston → Knoxville
15h 38m
5:15 AM - 3:53 PM • 1 stop
G4
Houston → Knoxville
3h 37m
5:32 PM - 6:49 PM • nonstop
$1076
United Airlines
Jul 01 - Jul 05, Economy
UA
Houston → Knoxville
10h 23m
8:30 AM - 3:53 PM • 1 stop
UA
Houston → Knoxville
8h 56m
6:00 AM - 10:36 AM • 1 stop
$1227
United Airlines

Fly from Houston to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Houston to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Houston to Knoxville Flights

What are the airports in Houston?
HOU
What’s the most popular airline flying from HOU to TYS?
The most popular airline flying from Houston to Knoxville are
Can I fly from HOU to TYS non-stop?
Yes, you can fly HOU to TYS non-stop on
Which airlines fly nonstop between Houston and Knoxville?
The non-stop flights between Houston and Knoxville are .
What’s the earliest departure time from HOU to TYS Airport?
The earliest flight leaves HOU at 5:00 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Houston to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from HOU to TYS?
Read the fare rules of the Houston to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Houston and Knoxville?
operate flights between Houston and Knoxville
How long does a flight from Houston to Knoxville take?
It takes approximately 2 hour to fly non-stop from HOU to TYS, which is 781.81 miles by air.
Which airlines provide the cheapest flights from Houston (HOU) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from HOU were found on DL : USD 314
Do I need a passport to fly between HOU and TYS?
No
What’s the latest departure time from HOU to TYS ?
The last flight leaves HOU at 11:5500 am

Houston (HOU) to Knoxville (TYS): Airport Information

Origin Airport William P Hobby , Houston, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 782 miles

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