Cheap Flight Tickets from Minneapolis (MSP) to Knoxville (TYS), Starting at $257

Good to Know: Cheapest and Fastest MSP - TYS Flights

Useful information for finding best airline tickets from Minneapolis-St Paul International/Wold-Chamberlain to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$257

DL Delta Airlines • 1 stop • 12h 7m

Nov 13 – Nov 17

The cheapest round trip flight from Minneapolis to Knoxville (MSP-TYS-MSP) is currently $257

🔍 Search Flights

Cheapest Direct Flight

$493

DL Delta Airlines • nonstop • 3h 37m

Nov 13

The cheapest nonstop flight from Minneapolis to Knoxville (MSP-TYS) is currently $493

🔍 Search Flights

Fastest Flight

3h 36m

The fastest nonstop flight from Minneapolis to Knoxville (MSP-TYS) takes 3h 36m

Top Airlines Flying from Minneapolis to Knoxville

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Minneapolis (MSP) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Minneapolis to Knoxville. Ideal for travelers with confirmed return itineraries.

Nov 13 - Nov 17, Economy
DL
Minneapolis → Knoxville
12h 7m
7:05 AM - 5:22 PM • 1 stop
DL
Minneapolis → Knoxville
3h 55m
6:30 PM - 8:05 PM • nonstop
$257
Delta Airlines
Nov 13 - Nov 17, Economy
DL
Minneapolis → Knoxville
12h 7m
8:55 AM - 5:22 PM • 1 stop
DL
Minneapolis → Knoxville
3h 55m
6:30 PM - 8:05 PM • nonstop
$257
Delta Airlines
Nov 13 - Nov 17, Economy
UA
Minneapolis → Knoxville
27h
5:52 PM - 11:12 AM • 1 stop
UA
Minneapolis → Knoxville
7h 18m
6:45 AM - 10:23 AM • 1 stop
$405
United Airlines
Nov 13 - Nov 17, Economy
DL
Minneapolis → Knoxville
3h 37m
1:03 PM - 4:20 PM • nonstop
DL
Minneapolis → Knoxville
8h 49m
12:34 PM - 5:03 PM • 1 stop
$503
Delta Airlines
Nov 13 - Nov 17, Economy
UA
Minneapolis → Knoxville
41h 47m
8:00 AM - 10:07 AM • 1 stop
UA
Minneapolis → Knoxville
7h 18m
6:45 AM - 10:23 AM • 1 stop
$948
United Airlines
Nov 13 - Nov 17, Economy
AA
Minneapolis → Knoxville
32h 26m
2:09 PM - 10:55 AM • 1 stop
AA
Minneapolis → Knoxville
6h 57m
11:33 AM - 2:50 PM • 1 stop
$987
American Airlines

Fly from Minneapolis to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Minneapolis to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Minneapolis to Knoxville Flights

What are the airports in Minneapolis?
MSP
What’s the most popular airline flying from MSP to TYS?
The most popular airline flying from Minneapolis to Knoxville are
Can I fly from MSP to TYS non-stop?
Yes, you can fly MSP to TYS non-stop on
Which airlines fly nonstop between Minneapolis and Knoxville?
The non-stop flights between Minneapolis and Knoxville are .
What’s the earliest departure time from MSP to TYS Airport?
The earliest flight leaves MSP at 7:05 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Minneapolis to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from MSP to TYS?
Read the fare rules of the Minneapolis to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Minneapolis and Knoxville?
operate flights between Minneapolis and Knoxville
How long does a flight from Minneapolis to Knoxville take?
It takes approximately 2 hour to fly non-stop from MSP to TYS, which is 792.0 miles by air.
Which airlines provide the cheapest flights from Minneapolis (MSP) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from MSP were found on DL : USD 503
Do I need a passport to fly between MSP and TYS?
No
What’s the latest departure time from MSP to TYS ?
The last flight leaves MSP at 7:55 pm

Minneapolis (MSP) to Knoxville (TYS): Airport Information

Origin Airport Minneapolis-St Paul International/Wold-Chamberlain, Minneapolis, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 792 miles

More Flight Options for Minneapolis (MSP) and Knoxville (TYS)

Why Fareleaders for MSP to TYS Plane Tickets

Lowest Prices
Lowest Prices
Uncover the best deals on Minneapolis to Knoxville flights by comparing fares from hundreds of airlines and agencies.
New Deals
New Deals Everyday
Get the best prices on MSP to TYS flights—we update our fares daily so you never miss a saving.
Best Travel Options
No Service Fees
Compare hundreds of Minneapolis to Knoxville flights and secure the best deals—we never add any service fees.
Get Fare Drop Alert
Be the first to know when fares drop for the Minneapolis (MSP) to Knoxville (TYS)
Terms and Conditions*