Lowest Prices
Uncover the best deals on New Orleans to Knoxville flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest MSY - TYS Flights
Useful information for finding best airline tickets from Louis Armstrong New Orleans International to McGhee Tyson on your next trip.
Cheapest Round Trip Flight
$340
Southwest Airlines
• 2 stops
• 14h 15m
Dec 03 – Dec 07
The cheapest round trip flight from New Orleans to Knoxville (MSY-TYS-MSY) is currently $340
Fastest Flight
6h 47m
The fastest nonstop flight from New Orleans to Knoxville (MSY-TYS) takes 6h 47m
Top Airlines Flying from New Orleans to Knoxville
Latest Flight Deals from New Orleans (MSY) to Knoxville (TYS)
Compare and book low fare round-trip air tickets from New Orleans to Knoxville. Ideal for travelers with confirmed return itineraries.
Dec 03 - Dec 07, Economy
New Orleans → Knoxville
14h 15m
- • 2 stops
New Orleans → Knoxville
5h 37m
- • 1 stop
Southwest Airlines
Dec 03 - Dec 07, Economy
New Orleans → Knoxville
15h 51m
9:40 AM - 8:31 PM • 1 stop
New Orleans → Knoxville
10h 1m
9:00 AM - 2:01 PM • 1 stop
Breeze Airways
Dec 03 - Dec 07, Economy
New Orleans → Knoxville
6h 47m
- • 1 stop
New Orleans → Knoxville
43h 55m
- • 1 stop
Delta Airlines
Dec 03 - Dec 07, Economy
New Orleans → Knoxville
7h 5m
7:40 AM - 6:33 PM • 1 stop
New Orleans → Knoxville
5h 37m
4:01 PM - 6:38 PM • 1 stop
Delta Airlines
Dec 03 - Dec 07, Economy
New Orleans → Knoxville
10h 7m
- • 1 stop
New Orleans → Knoxville
5h 37m
- • 1 stop
American Airlines
FAQs on New Orleans to Knoxville Flights
What are the airports in New Orleans?
MSY
What’s the most popular airline flying from MSY to TYS?
The most popular airline flying from New Orleans to Knoxville are
Can I fly from MSY to TYS non-stop?
NO
Which airlines fly nonstop between New Orleans and Knoxville?
The non-stop flights between New Orleans and Knoxville are .
What’s the earliest departure time from MSY to TYS Airport?
The earliest flight leaves MSY at 7:40 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my New Orleans to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from MSY to TYS?
Read the fare rules of the New Orleans to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from New Orleans and Knoxville?
operate flights between New Orleans and Knoxville
How long does a flight from New Orleans to Knoxville take?
It takes approximately 2 hour to fly non-stop from MSY to TYS, which is 541.32 miles by air.
Which airlines provide the cheapest flights from New Orleans (MSY) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from MSY were found on DL : USD 360
Do I need a passport to fly between MSY and TYS?
No
What’s the latest departure time from MSY to TYS ?
The last flight leaves MSY at 10:5500 am
New Orleans (MSY) to Knoxville (TYS): Airport Information
| Origin Airport | Louis Armstrong New Orleans International , New Orleans, US |
| Destination Airport | McGhee Tyson , Knoxville, US |
| Distance | 541 miles |
More Flight Options for New Orleans (MSY) and Knoxville (TYS)
Flights from New Orleans (MSY)
to New York (NYC)
Flights from New Orleans (MSY)
to Orlando (MCO)
Flights from New Orleans (MSY)
to Fort Lauderdale (FLL)
Flights from New Orleans (MSY)
to Miami (MIA)
Flights from New Orleans (MSY)
to Los Angeles (LAX)
Flights from New Orleans (MSY)
to Las Vegas (LAS)
Flights from New Orleans (MSY)
to San Antonio (SAT)
Flights from New Orleans (MSY)
to Atlanta (ATL)
Flights from New Orleans (MSY)
to Denver (DEN)
Flights from New Orleans (MSY)
to San Diego (SAN)
Flights from New Orleans (MSY)
to Oakland (OAK)
Flights from New Orleans (MSY)
to New York (LGA)
Flights from New Orleans (MSY)
to Washington (DCA)
Flights from New Orleans (MSY)
to New York (JFK)
Flights from New Orleans (MSY)
to Knoxville (TYS)
Flights from New Orleans (MSY)
to Austin (AUS)
Flights from New Orleans (MSY)
to Orlando (ORL)
Flights from New Orleans (MSY)
to Boston (BOS)
Flights from New Orleans (MSY)
to La Mesa (SAP)
Flights from New Orleans (MSY)
to Sacramento (SMF)
Flights from Los Angeles (LAX)
to Knoxville (TYS)
Flights from Raleigh/Durham (RDU)
to Knoxville (TYS)
Flights from Las Vegas (LAS)
to Knoxville (TYS)
Flights from Newark (EWR)
to Knoxville (TYS)
Flights from Washington (DCA)
to Knoxville (TYS)
Flights from Cleveland (CLE)
to Knoxville (TYS)
Flights from San Antonio (SAT)
to Knoxville (TYS)
Flights from New Orleans (MSY)
to Knoxville (TYS)
Flights from Myrtle Beach (MYR)
to Knoxville (TYS)
Flights from Memphis (MEM)
to Knoxville (TYS)
Flights from Orlando (MCO)
to Knoxville (TYS)
Flights from Ontario (ONT)
to Knoxville (TYS)
Flights from Ontario (ONT)
to Knoxville (TYS)
Flights from Baltimore (BWI)
to Knoxville (TYS)
Flights from Chicago (ORD)
to Knoxville (TYS)
Flights from Minneapolis (MSP)
to Knoxville (TYS)
Flights from Minneapolis (MSP)
to Knoxville (TYS)
Flights from Buffalo (BUF)
to Knoxville (TYS)
Flights from Portland (PDX)
to Knoxville (TYS)
Flights from Dallas (DFW)
to Knoxville (TYS)
Cheap flights to North America (NA)
Cheap flights to United States (US)
Cheap flights to Louisiana (US-LA)
Cheap flights to Tennessee (US-TN)
Cheap flights from North America (NA)
Cheap flights from United States (US)
Cheap flights from Louisiana (US-LA)
Cheap flights from Tennessee (US-TN)
Flights to New Orleans (MSY)
Flights to Knoxville (TYS)
Flights from New Orleans (MSY)
Flights from Knoxville (TYS)
Flights from Knoxville (TYS)
to New Orleans (MSY)
Why Fareleaders for MSY to TYS Plane Tickets
New Deals Everyday
Get the best prices on MSY to TYS flights—we update our fares daily so you never miss a saving.
No Service Fees
Compare hundreds of New Orleans to Knoxville flights and secure the best deals—we never add any service fees.