Cheap Flight Tickets from Chicago (MDW) to Knoxville (TYS), Starting at $433

Good to Know: Cheapest and Fastest MDW - TYS Flights

Useful information for finding best airline tickets from Chicago Midway International to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$433

WN Southwest Airlines • 1 stop • 15h 20m

Jul 19 – Jul 28

The cheapest round trip flight from Chicago to Knoxville (MDW-TYS-MDW) is currently $433

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Fastest Flight

5h 10m

The fastest nonstop flight from Chicago to Knoxville (MDW-TYS) takes 5h 10m

Top Airlines Flying from Chicago to Knoxville

Southwest Airlines-WN

Southwest Airlines

Latest Flight Deals from Chicago (MDW) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Chicago to Knoxville. Ideal for travelers with confirmed return itineraries.

Jul 19 - Jul 28, Economy
WN
Chicago → Knoxville
15h 20m
12:10 PM - 10:30 PM • 1 stop
WN
Chicago → Knoxville
13h 45m
12:45 PM - 8:10 PM • 1 stop
$433
Southwest Airlines
Jul 19 - Jul 28, Economy
WN
Chicago → Knoxville
11h 50m
10:10 AM - 6:20 PM • 1 stop
WN
Chicago → Knoxville
13h 35m
2:45 PM - 10:00 PM • 1 stop
$433
Southwest Airlines
Jul 19 - Jul 28, Economy
WN
Chicago → Knoxville
5h 10m
7:55 AM - 12:05 PM • 1 stop
WN
Chicago → Knoxville
13h 45m
12:45 PM - 8:10 PM • 1 stop
$433
Southwest Airlines
Jul 19 - Jul 28, Economy
WN
Chicago → Knoxville
7h 35m
6:10 AM - 12:05 PM • 1 stop
WN
Chicago → Knoxville
10h 35m
7:10 AM - 12:45 PM • 2 stops
$439
Southwest Airlines
Jul 19 - Jul 28, Economy
WN
Chicago → Knoxville
9h
2:40 PM - 9:20 PM • 2 stops
WN
Chicago → Knoxville
10h 50m
8:10 AM - 2:00 PM • 1 stop
$439
Southwest Airlines
Jul 19 - Jul 28, Economy
WN
Chicago → Knoxville
15h 5m
11:15 AM - 9:20 PM • 2 stops
WN
Chicago → Knoxville
5h 15m
6:55 PM - 9:10 PM • 1 stop
$439
Southwest Airlines

Fly from Chicago to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Chicago to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Chicago to Knoxville Flights

What are the airports in Chicago?
ORD,MDW
What’s the most popular airline flying from MDW to TYS?
The most popular airline flying from Chicago to Knoxville are
Can I fly from MDW to TYS non-stop?
NO
Which airlines fly nonstop between Chicago and Knoxville?
The non-stop flights between Chicago and Knoxville are .
What’s the earliest departure time from MDW to TYS Airport?
The earliest flight leaves MDW at 6:10 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Chicago to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from MDW to TYS?
Read the fare rules of the Chicago to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Chicago and Knoxville?
operate flights between Chicago and Knoxville
How long does a flight from Chicago to Knoxville take?
It takes approximately 2 hour to fly non-stop from MDW to TYS, which is 459.25 miles by air.
Which airlines provide the cheapest flights from Chicago (MDW) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from MDW were found on WN : USD 433
Do I need a passport to fly between MDW and TYS?
No
What’s the latest departure time from MDW to TYS ?
The last flight leaves MDW at 2:40 pm

Chicago (MDW) to Knoxville (TYS): Airport Information

Origin Airport Chicago Midway International , Chicago, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 459 miles

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