Cheap Flight Tickets from Houston (IAH) to Knoxville (TYS), Starting at $160

Good to Know: Cheapest and Fastest IAH - TYS Flights

Useful information for finding best airline tickets from George Bush Intercontinental Houston to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$271

UA United Airlines • 1 stop • 12m

Aug 20 – Aug 23

The cheapest round trip flight from Houston to Knoxville (IAH-TYS-IAH) is currently $271

🔍 Search Flights

Cheapest One way Flight

$247

F9 Frontier Airlines • 2 stops • 38h 24m

Aug 19

The cheapest one way flight from Houston to Knoxville (IAH-TYS) is currently $247

🔍 Search Flights

Cheapest Direct Flight

$160

UA United Airlines • nonstop • 2m

Aug 19

The cheapest nonstop flight from Houston to Knoxville (IAH-TYS) is currently $160

🔍 Search Flights

Fastest Flight

2m

The fastest nonstop flight from Houston to Knoxville (IAH-TYS) takes 2m

Top Airlines Flying from Houston to Knoxville

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Southwest Airlines-WN

Southwest Airlines

Latest Flight Deals from Houston (IAH) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Houston to Knoxville. Ideal for travelers with confirmed return itineraries.

Aug 20 - Aug 23, Economy
UA
Houston → Knoxville
12m
7:20 AM - 2:37 PM • 1 stop
UA
Houston → Knoxville
14m
4:50 PM - 10:56 PM • 1 stop
$271
United Airlines
Aug 20 - Aug 23, Economy
AA
Houston → Knoxville
10h 56m
5:00 AM - 12:56 PM • 1 stop
AA
Houston → Knoxville
7h 34m
8:05 PM - 11:59 PM • 1 stop
$418
American Airlines
Aug 20 - Aug 23, Economy
AA
Houston → Knoxville
7h 18m
6:06 AM - 11:44 AM • 1 stop
AA
Houston → Knoxville
7h 34m
8:05 PM - 11:59 PM • 1 stop
$453
American Airlines
Aug 20 - Aug 23, Economy
AA
Houston → Knoxville
5h 53m
9:04 AM - 5:34 PM • 1 stop
AA
Houston → Knoxville
5h 41m
8:05 PM - 11:59 PM • 1 stop
$473
American Airlines
Aug 20 - Aug 23, Economy
UA
Houston → Knoxville
3h 40m
2:57 PM - 6:17 PM • nonstop
UA
Houston → Knoxville
13h 53m
5:45 AM - 1:18 PM • 1 stop
$494
United Airlines
Aug 20 - Aug 23, Economy
DL
Houston → Knoxville
8h 39m
3:15 PM - 9:34 PM • 1 stop
DL
Houston → Knoxville
5h 57m
5:40 AM - 8:37 AM • 1 stop
$794
Delta Airlines

Fly from Houston to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Houston to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Houston to Knoxville Flights

What are the airports in Houston?
IAH
What’s the most popular airline flying from IAH to TYS?
The most popular airline flying from Houston to Knoxville are
Can I fly from IAH to TYS non-stop?
Yes, you can fly IAH to TYS non-stop on
Which airlines fly nonstop between Houston and Knoxville?
The non-stop flights between Houston and Knoxville are .
What’s the earliest departure time from IAH to TYS Airport?
The earliest flight leaves IAH at 5:00 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Houston to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from IAH to TYS?
Read the fare rules of the Houston to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Houston and Knoxville?
operate flights between Houston and Knoxville
How long does a flight from Houston to Knoxville take?
It takes approximately 2 hour to fly non-stop from IAH to TYS, which is 771.46 miles by air.
Which airlines provide the cheapest flights from Houston (IAH) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from IAH were found on F9 : USD 247
Do I need a passport to fly between IAH and TYS?
No
What’s the latest departure time from IAH to TYS ?
The last flight leaves IAH at 6:25 pm

Houston (IAH) to Knoxville (TYS): Airport Information

Origin Airport George Bush Intercontinental Houston , Houston, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 771 miles

More Flight Options for Houston (IAH) and Knoxville (TYS)

Why Fareleaders for IAH to TYS Plane Tickets

Lowest Prices
Lowest Prices
Uncover the best deals on Houston to Knoxville flights by comparing fares from hundreds of airlines and agencies.
New Deals
New Deals Everyday
Get the best prices on IAH to TYS flights—we update our fares daily so you never miss a saving.
Best Travel Options
No Service Fees
Compare hundreds of Houston to Knoxville flights and secure the best deals—we never add any service fees.
Get Fare Drop Alert
Be the first to know when fares drop for the Houston (IAH) to Knoxville (TYS)
Terms and Conditions*