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Uncover the best deals on Houston to Knoxville flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest IAH - TYS Flights
Useful information for finding best airline tickets from George Bush Intercontinental Houston to McGhee Tyson on your next trip.
Cheapest Round Trip Flight
$246
Delta Airlines
• 1 stop
• 15h 44m
Nov 25 – Nov 30
The cheapest round trip flight from Houston to Knoxville (IAH-TYS-IAH) is currently $246
Fastest Flight
8h 39m
The fastest nonstop flight from Houston to Knoxville (IAH-TYS) takes 8h 39m
Latest Flight Deals from Houston (IAH) to Knoxville (TYS)
Compare and book low fare round-trip air tickets from Houston to Knoxville. Ideal for travelers with confirmed return itineraries.
Nov 25 - Nov 30, Economy
Houston → Knoxville
15h 44m
8:05 AM - 6:49 PM • 1 stop
Houston → Knoxville
8h 57m
7:22 PM - 11:59 PM • 1 stop
Delta Airlines
Nov 25 - Nov 30, Economy
Houston → Knoxville
14h 2m
12:30 PM - 10:12 PM • 1 stop
Houston → Knoxville
8h 57m
7:22 PM - 11:59 PM • 1 stop
Delta Airlines
Nov 25 - Nov 30, Economy
Houston → Knoxville
18h 24m
8:05 AM - 8:09 PM • 1 stop
Houston → Knoxville
8h 57m
7:22 PM - 11:59 PM • 1 stop
Delta Airlines
Nov 25 - Nov 30, Economy
Houston → Knoxville
12h 29m
10:00 AM - 6:49 PM • 1 stop
Houston → Knoxville
8h 57m
7:22 PM - 11:59 PM • 1 stop
Delta Airlines
Nov 25 - Nov 30, Economy
Houston → Knoxville
17h 29m
7:00 AM - 6:49 PM • 1 stop
Houston → Knoxville
8h 57m
7:22 PM - 11:59 PM • 1 stop
Delta Airlines
FAQs on Houston to Knoxville Flights
What are the airports in Houston?
IAH
What’s the most popular airline flying from IAH to TYS?
The most popular airline flying from Houston to Knoxville are
Can I fly from IAH to TYS non-stop?
NO
Which airlines fly nonstop between Houston and Knoxville?
The non-stop flights between Houston and Knoxville are .
What’s the earliest departure time from IAH to TYS Airport?
The earliest flight leaves IAH at 7:00 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Houston to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from IAH to TYS?
Read the fare rules of the Houston to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Houston and Knoxville?
operate flights between Houston and Knoxville
How long does a flight from Houston to Knoxville take?
It takes approximately 2 hour to fly non-stop from IAH to TYS, which is 771.46 miles by air.
Which airlines provide the cheapest flights from Houston (IAH) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from IAH were found on DL : USD 270
Do I need a passport to fly between IAH and TYS?
No
What’s the latest departure time from IAH to TYS ?
The last flight leaves IAH at 12:30 pm
Hotels in Knoxville (TYS)
5 hotels near McGhee Tyson — compare rates from top booking sites.
4-star hotel
Hilton Knoxville Airport
📍 2001 Alcoa Highway, Alcoa, Tennessee 37701-3163
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4-star hotel
Brookstone Lodge
📍 4 Roberts Rd, Asheville, North Carolina 28803
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4-star hotel
Baskins Creek Condos By Wyndham Vacation Rentals
📍 215 Woliss Ln, Gatlinburg, Tennessee 37738
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4-star hotel
Deer Ridge Mountain Resort
📍 3710 Weber Rd., Gatlinburg, Tennessee 37738
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4-star hotel
Christopher Place
📍 1500 Pinnacles Way, Newport, Tennessee 37821
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Hotel Deals in Knoxville (TN)
Wyndham Hotels & Resorts
Travelodge by Wyndham Knoxville East
7.6/10
★★☆☆☆
Hotel
52.0 rooms
✓ Free WiFi
📍 7471 Crosswood Blvd, Knoxville (TN), Tennessee
Travelodge by Wyndham Knoxville East offers top-notch services and amenities, ensuring guests experience utmost comfort.Share your photos and respond to emails at your convenience, thanks to the free…
Check-in 03:00 PM · Check-out 11:00 AM
$44/night
View Deal
-20.0%
OYO Rooms
OYO Hotel Knoxville TN Cedar Bluff I-40
6.1/10
★★★☆☆
Hotel
88.0 rooms
✓ Free WiFi
📍 317 N Cedar Bluff Rd, Knoxville (TN), Tennessee
OYO Hotel Knoxville TN Cedar Bluff I-40 provides flawless service and all the necessary facilities for visitors. Stay connected with your associates, as complimentary Wi-Fi is available during your e…
Check-in 03:00 PM · Check-out 11:00 AM
$60/night
View Deal
Wyndham Hotels & Resorts
Days Inn by Wyndham Knoxville East
7.2/10
★★★☆☆
Hotel
115.0 rooms
✓ Free WiFi
✓ Breakfast
📍 5423 Asheville Highway, Knoxville (TN)
At Days Inn by Wyndham Knoxville East, exceptional service and top-notch amenities create a memorable experience for guests.Complimentary internet access is available in the hotel to ensure you stay …
Check-in 03:00 PM · Check-out 11:00 AM
$61/night
View Deal
Wyndham Hotels & Resorts
Americas Best Value Inn Knoxville Downtown North
7.7/10
★★☆☆☆
Hotel
105.0 rooms
✓ Free WiFi
📍 341 Merchants Drive, Knoxville (TN), Tennessee
Super 8 By Wyndham Knoxville Downtown Area offers top-notch services and amenities, ensuring guests experience utmost comfort.Share your photos and respond to emails at your convenience, thanks to th…
Check-in 02:00 PM · Check-out 11:00 AM
$62/night
View Deal
Red Roof Inn
Red Roof PLUS+ & Suites Knoxville West-Cedar Bluff
7.5/10
★★★☆☆
Hotel
121.0 rooms
✓ Free WiFi
✓ Breakfast
📍 208 Market Pl Blvd, Knoxville (TN), Tennessee
Experience an abundance of unparalleled facilities and features at Red Roof PLUS+ & Suites Knoxville West-Cedar Bluff. Maintain seamless communication using the complimentary Wi-Fi at hotel. For visi…
Check-in 02:00 PM · Check-out 11:00 AM
$64/night
View Deal
Wyndham Hotels & Resorts
Baymont by Wyndham Knoxville I-75
6.9/10
★★★☆☆
Hotel
116.0 rooms
✓ Free WiFi
✓ Breakfast
📍 6712 Central Avenue Pike, Knoxville (TN)
At Baymont by Wyndham Knoxville I-75, exceptional service and top-notch amenities create a memorable experience for guests.Complimentary internet access is available in the hotel to ensure you stay c…
Check-in 03:00 PM · Check-out 11:00 AM
$65/night
View Deal
Red Roof Inn
Red Roof Inn Knoxville North - Merchants Drive
6.9/10
★★☆☆☆
Hotel
91.0 rooms
✓ Free WiFi
✓ Breakfast
📍 5334 Central Ave Pike, Knoxville (TN), Tennessee
Experience an abundance of unparalleled facilities and features at Red Roof Inn Knoxville North - Merchants Drive. Maintain seamless communication using the complimentary Wi-Fi at hotel. For visitors…
Check-in 03:00 PM · Check-out 11:00 AM
$66/night
View Deal
Wyndham Hotels & Resorts
Baymont by Wyndham Knoxville/Cedar Bluff
8.5/10
★★★☆☆
Hotel
122.0 rooms
✓ Free WiFi
✓ Breakfast
📍 209 Market Place Boulevard, Knoxville (TN), Tennessee
Experience an abundance of unparalleled facilities and features at Baymont by Wyndham Knoxville/Cedar Bluff.Share your photos and respond to emails at your convenience, thanks to the free Wi-Fi inter…
Check-in 03:00 PM · Check-out 12:00 PM
$69/night
View Deal
Best Western International
Best Western Plus Strawberry Inn & Suites
8.4/10
Hotel
64.0 rooms
✓ Free WiFi
✓ Breakfast
📍 7260 Saddlerack Street, Knoxville (TN), Tennessee
Best Western Plus Strawberry Inn and Suites provides flawless service and all the necessary facilities for visitors.Remain linked during your visit by utilizing the complimentary internet access avai…
Check-in 03:00 PM · Check-out 11:00 AM
$72/night
View Deal
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Houston (IAH) to Knoxville (TYS): Airport Information
| Origin Airport | George Bush Intercontinental Houston , Houston, US |
| Destination Airport | McGhee Tyson , Knoxville, US |
| Distance | 771 miles |
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