Cheap Flight Tickets from Knoxville (TYS) to Chicago (ORD), Starting at $187

Good to Know: Cheapest and Fastest TYS - ORD Flights

Useful information for finding best airline tickets from McGhee Tyson to Chicago O'Hare International on your next trip.

Cheapest Round Trip Flight

$187

DL Delta Airlines • 1 stop • 12h 3m

Sep 05 – Sep 09

The cheapest round trip flight from Knoxville to Chicago (TYS-ORD-TYS) is currently $187

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Cheapest One way Flight

$198

DL Delta Airlines • 1 stop • 18h 49m

Sep 18

The cheapest one way flight from Knoxville to Chicago (TYS-ORD) is currently $198

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Cheapest Direct Flight

$365

UA United Airlines • nonstop • 2h 36m

Aug 21

The cheapest nonstop flight from Knoxville to Chicago (TYS-ORD) is currently $365

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Fastest Flight

2h 36m

The fastest nonstop flight from Knoxville to Chicago (TYS-ORD) takes 2h 36m

Top Airlines Flying from Knoxville to Chicago

Delta Airline, DL

Delta Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Knoxville (TYS) to Chicago (ORD)

Compare and book low fare round-trip air tickets from Knoxville to Chicago. Ideal for travelers with confirmed return itineraries.

Sep 05 - Sep 09, Economy
DL
Knoxville → Chicago
12h 3m
10:28 AM - 4:51 PM • 1 stop
DL
Knoxville → Chicago
5h 39m
6:05 AM - 10:44 AM • 1 stop
$187
Delta Airlines
Sep 05 - Sep 09, Economy
DL
Knoxville → Chicago
7h 7m
7:15 AM - 10:42 AM • 1 stop
DL
Knoxville → Chicago
8h 31m
6:40 AM - 12:51 PM • 1 stop
$287
Delta Airlines
Sep 05 - Sep 09, Economy
DL
Knoxville → Chicago
8h 59m
11:38 AM - 4:17 PM • 1 stop
DL
Knoxville → Chicago
5h 39m
6:05 AM - 10:44 AM • 1 stop
$287
Delta Airlines
Sep 05 - Sep 09, Economy
DL
Knoxville → Chicago
7h 14m
1:17 PM - 4:51 PM • 1 stop
DL
Knoxville → Chicago
7h 37m
4:30 PM - 10:27 PM • 1 stop
$287
Delta Airlines
Sep 05 - Sep 09, Economy
DL
Knoxville → Chicago
7h 35m
5:00 PM - 8:55 PM • 1 stop
DL
Knoxville → Chicago
7h 37m
4:30 PM - 10:27 PM • 1 stop
$287
Delta Airlines
Sep 05 - Sep 09, Economy
AA
Knoxville → Chicago
7h 31m
7:00 AM - 10:51 AM • 1 stop
AA
Knoxville → Chicago
2h 27m
1:24 PM - 4:11 PM • nonstop
$341
American Airlines

Fly from Knoxville to Chicago with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Knoxville to Chicago? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Knoxville to Chicago Flights

What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to ORD?
The most popular airline flying from Knoxville to Chicago are
Can I fly from TYS to ORD non-stop?
Yes, you can fly TYS to ORD non-stop on
Which airlines fly nonstop between Knoxville and Chicago?
The non-stop flights between Knoxville and Chicago are .
What’s the earliest departure time from TYS to ORD Airport?
The earliest flight leaves TYS at 6:30 am and lands in ORD - Chicago O'Hare International
What are the airports in Chicago?
MDW,ORD
Can I make changes to my Knoxville to Chicago flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to ORD?
Read the fare rules of the Knoxville to Chicago air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Chicago?
operate flights between Knoxville and Chicago
How long does a flight from Knoxville to Chicago take?
It takes approximately 2 hour to fly non-stop from TYS to ORD, which is 474.67 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Chicago (ORD) ?
In the past couple of days, the cheapest tickets to ORD from TYS were found on UA : USD 553
Do I need a passport to fly between TYS and ORD?
No
What’s the latest departure time from TYS to ORD ?
The last flight leaves TYS at 11:1500 am

Knoxville (TYS) to Chicago (ORD): Airport Information

Origin Airport McGhee Tyson , Knoxville, US
Destination Airport Chicago O'Hare International , Chicago, US
Distance 475 miles

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