Cheap Flight Tickets from Knoxville (TYS) to Chicago (ORD), Starting at $168

Good to Know: Cheapest and Fastest TYS - ORD Flights

Useful information for finding best airline tickets from McGhee Tyson to Chicago O'Hare International on your next trip.

Cheapest Round Trip Flight

$168

DL Delta Airlines • 1 stop • 6h 46m

Sep 11 – Sep 13

The cheapest round trip flight from Knoxville to Chicago (TYS-ORD-TYS) is currently $168

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Cheapest Direct Flight

$219

UA United Airlines • nonstop • 2h 35m

Sep 11

The cheapest nonstop flight from Knoxville to Chicago (TYS-ORD) is currently $219

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Fastest Flight

2h 35m

The fastest nonstop flight from Knoxville to Chicago (TYS-ORD) takes 2h 35m

Top Airlines Flying from Knoxville to Chicago

Delta Airline, DL

Delta Airlines

Latest Flight Deals from Knoxville (TYS) to Chicago (ORD)

Compare and book low fare round-trip air tickets from Knoxville to Chicago. Ideal for travelers with confirmed return itineraries.

Sep 11 - Sep 13, Economy
DL
Knoxville → Chicago
6h 46m
1:31 PM - 4:37 PM • 1 stop
DL
Knoxville → Chicago
7h 10m
6:25 PM - 11:55 PM • 1 stop
$168
Delta Airlines
Sep 11 - Sep 13, Economy
AA
Knoxville → Chicago
2h 38m
11:20 AM - 12:18 PM • nonstop
AA
Knoxville → Chicago
6h 48m
4:45 PM - 9:53 PM • 1 stop
$247
American Airlines
Sep 11 - Sep 13, Economy
AA
Knoxville → Chicago
3h 24m
1:22 PM - 2:26 PM • nonstop
AA
Knoxville → Chicago
6h 53m
5:18 AM - 10:31 AM • 1 stop
$247
American Airlines
Aug 01 - Aug 01, Economy
DL
Knoxville → Chicago
7h 39m
10:26 AM - 2:25 PM • 1 stop
DL
Knoxville → Chicago
7h 2m
6:22 PM - 11:44 PM • 1 stop
$1089
Delta Airlines
Aug 01 - Aug 01, Economy
DL
Knoxville → Chicago
7h 2m
9:05 AM - 12:27 PM • 1 stop
DL
Knoxville → Chicago
10h 6m
3:55 PM - 11:01 PM • 1 stop
$1089
Delta Airlines
Aug 01 - Aug 01, Economy
DL
Knoxville → Chicago
10h 20m
9:05 AM - 2:25 PM • 1 stop
DL
Knoxville → Chicago
7h 2m
6:22 PM - 11:44 PM • 1 stop
$1089
Delta Airlines

Fly from Knoxville to Chicago with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Knoxville to Chicago? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Knoxville to Chicago Flights

What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to ORD?
The most popular airline flying from Knoxville to Chicago are
Can I fly from TYS to ORD non-stop?
Yes, you can fly TYS to ORD non-stop on
Which airlines fly nonstop between Knoxville and Chicago?
The non-stop flights between Knoxville and Chicago are .
What’s the earliest departure time from TYS to ORD Airport?
The earliest flight leaves TYS at 6:00 am and lands in ORD - Chicago O'Hare International
What are the airports in Chicago?
MDW,ORD
Can I make changes to my Knoxville to Chicago flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to ORD?
Read the fare rules of the Knoxville to Chicago air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Chicago?
operate flights between Knoxville and Chicago
How long does a flight from Knoxville to Chicago take?
It takes approximately 2 hour to fly non-stop from TYS to ORD, which is 474.67 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Chicago (ORD) ?
In the past couple of days, the cheapest tickets to ORD from TYS were found on DL : USD 1089
Do I need a passport to fly between TYS and ORD?
No
What’s the latest departure time from TYS to ORD ?
The last flight leaves TYS at 8:15 pm

Knoxville (TYS) to Chicago (ORD): Airport Information

Origin Airport McGhee Tyson , Knoxville, US
Destination Airport Chicago O'Hare International , Chicago, US
Distance 475 miles

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