Cheap Flight Tickets from Knoxville (TYS) to Chicago (ORD), Starting at $479

Good to Know: Cheapest and Fastest TYS - ORD Flights

Useful information for finding best airline tickets from McGhee Tyson to Chicago O'Hare International on your next trip.

Cheapest Round Trip Flight

$484

AA American Airlines • nonstop • 3h 36m

Jun 24 – Jun 29

The cheapest round trip flight from Knoxville to Chicago (TYS-ORD-TYS) is currently $484

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Cheapest Direct Flight

$479

UA United Airlines • nonstop • 3h 28m

Jun 24

The cheapest nonstop flight from Knoxville to Chicago (TYS-ORD) is currently $479

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Fastest Flight

2h 39m

The fastest nonstop flight from Knoxville to Chicago (TYS-ORD) takes 2h 39m

Top Airlines Flying from Knoxville to Chicago

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Aeromexico Airline (AM)

Aeromexico

Latest Flight Deals from Knoxville (TYS) to Chicago (ORD)

Compare and book low fare round-trip air tickets from Knoxville to Chicago. Ideal for travelers with confirmed return itineraries.

Jun 24 - Jun 29, Economy
AA
Knoxville → Chicago
3h 36m
6:43 PM - 7:59 PM • nonstop
AA
Knoxville → Chicago
2h 33m
9:50 AM - 12:43 PM • nonstop
$484
American Airlines
Jun 24 - Jun 29, Economy
AA
Knoxville → Chicago
8h 22m
5:00 AM - 9:02 AM • 1 stop
AA
Knoxville → Chicago
2h 33m
9:50 AM - 12:43 PM • nonstop
$494
American Airlines
Jun 24 - Jun 29, Economy
AA
Knoxville → Chicago
7h 6m
6:07 PM - 9:33 PM • 1 stop
AA
Knoxville → Chicago
2h 28m
3:25 PM - 6:13 PM • nonstop
$494
American Airlines
Jun 24 - Jun 29, Economy
AA
Knoxville → Chicago
7h 23m
1:00 PM - 4:43 PM • 1 stop
AA
Knoxville → Chicago
2h 33m
8:05 AM - 10:58 AM • nonstop
$494
American Airlines
Jun 24 - Jun 29, Economy
UA
Knoxville → Chicago
8h 39m
10:10 AM - 2:29 PM • 1 stop
UA
Knoxville → Chicago
2h 29m
10:30 AM - 1:19 PM • nonstop
$509
United Airlines
Jun 24 - Jun 29, Economy
UA
Knoxville → Chicago
3h 21m
1:54 PM - 2:55 PM • nonstop
UA
Knoxville → Chicago
7h 27m
8:40 AM - 2:27 PM • 1 stop
$509
United Airlines

Fly from Knoxville to Chicago with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Knoxville to Chicago? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Knoxville to Chicago Flights

What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to ORD?
The most popular airline flying from Knoxville to Chicago are
Can I fly from TYS to ORD non-stop?
Yes, you can fly TYS to ORD non-stop on
Which airlines fly nonstop between Knoxville and Chicago?
The non-stop flights between Knoxville and Chicago are .
What’s the earliest departure time from TYS to ORD Airport?
The earliest flight leaves TYS at 5:00 am and lands in ORD - Chicago O'Hare International
What are the airports in Chicago?
MDW,ORD
Can I make changes to my Knoxville to Chicago flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to ORD?
Read the fare rules of the Knoxville to Chicago air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Chicago?
operate flights between Knoxville and Chicago
How long does a flight from Knoxville to Chicago take?
It takes approximately 2 hour to fly non-stop from TYS to ORD, which is 474.67 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Chicago (ORD) ?
In the past couple of days, the cheapest tickets to ORD from TYS were found on UA : USD 509
Do I need a passport to fly between TYS and ORD?
No
What’s the latest departure time from TYS to ORD ?
The last flight leaves TYS at 6:43 pm

Knoxville (TYS) to Chicago (ORD): Airport Information

Origin Airport McGhee Tyson , Knoxville, US
Destination Airport Chicago O'Hare International , Chicago, US
Distance 475 miles

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