Lowest Prices
Uncover the best deals on Knoxville to San Antonio flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest TYS - SAT Flights
Useful information for finding best airline tickets from McGhee Tyson to San Antonio International on your next trip.
Cheapest Round Trip Flight
$212
Delta Airlines
• 1 stop
• 11h 48m
Sep 03 – Sep 07
The cheapest round trip flight from Knoxville to San Antonio (TYS-SAT-TYS) is currently $212
Fastest Flight
6h 45m
The fastest nonstop flight from Knoxville to San Antonio (TYS-SAT) takes 6h 45m
Top Airlines Flying from Knoxville to San Antonio
Latest Flight Deals from Knoxville (TYS) to San Antonio (SAT)
Compare and book low fare round-trip air tickets from Knoxville to San Antonio. Ideal for travelers with confirmed return itineraries.
Sep 03 - Sep 07, Economy
Knoxville → San Antonio
11h 48m
7:30 AM - 1:38 PM • 1 stop
Knoxville → San Antonio
7h 19m
7:55 AM - 1:34 PM • 1 stop
Delta Airlines
Sep 03 - Sep 07, Economy
Knoxville → San Antonio
11h 56m
6:12 PM - 12:28 AM • 1 stop
Knoxville → San Antonio
7h 7m
2:43 PM - 8:10 PM • 1 stop
Delta Airlines
Sep 03 - Sep 07, Economy
Knoxville → San Antonio
6h 45m
2:05 PM - 5:10 PM • 1 stop
Knoxville → San Antonio
10h 50m
5:35 AM - 1:25 PM • 1 stop
Southwest Airlines
Sep 03 - Sep 07, Economy
Knoxville → San Antonio
8h 28m
5:40 AM - 9:48 AM • 1 stop
Knoxville → San Antonio
8h 53m
10:46 AM - 5:19 PM • 1 stop
Delta Airlines
Sep 03 - Sep 07, Economy
Knoxville → San Antonio
15h 50m
1:15 PM - 10:05 PM • 1 stop
Knoxville → San Antonio
13h 50m
6:25 AM - 3:55 PM • 1 stop
Southwest Airlines
FAQs on Knoxville to San Antonio Flights
What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to SAT?
The most popular airline flying from Knoxville to San Antonio are
Can I fly from TYS to SAT non-stop?
NO
Which airlines fly nonstop between Knoxville and San Antonio?
The non-stop flights between Knoxville and San Antonio are .
What’s the earliest departure time from TYS to SAT Airport?
The earliest flight leaves TYS at 5:40 am and lands in SAT - San Antonio International
What are the airports in San Antonio?
SAT
Can I make changes to my Knoxville to San Antonio flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to SAT?
Read the fare rules of the Knoxville to San Antonio air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and San Antonio?
operate flights between Knoxville and San Antonio
How long does a flight from Knoxville to San Antonio take?
It takes approximately 3 hour to fly non-stop from TYS to SAT, which is 946.69 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to San Antonio (SAT) ?
In the past couple of days, the cheapest tickets to SAT from TYS were found on DL : USD 212
Do I need a passport to fly between TYS and SAT?
No
What’s the latest departure time from TYS to SAT ?
The last flight leaves TYS at 6:12 pm
Knoxville (TYS) to San Antonio (SAT): Airport Information
| Origin Airport | McGhee Tyson , Knoxville, US |
| Destination Airport | San Antonio International , San Antonio, US |
| Distance | 947 miles |
More Flight Options for Knoxville (TYS) and San Antonio (SAT)
Flights from Knoxville (TYS)
to Fort Lauderdale (FLL)
Flights from Knoxville (TYS)
to Boston (BOS)
Flights from Knoxville (TYS)
to Indianapolis (IND)
Flights from Knoxville (TYS)
to Dallas (DFW)
Flights from Knoxville (TYS)
to Myrtle Beach (MYR)
Flights from Knoxville (TYS)
to Las Vegas (LAS)
Flights from Knoxville (TYS)
to Phoenix (PHX)
Flights from Knoxville (TYS)
to Kansas City (MCI)
Flights from Knoxville (TYS)
to San Jose (SJO)
Flights from Knoxville (TYS)
to Fort Myers (RSW)
Flights from Knoxville (TYS)
to Detroit (DTW)
Flights from Knoxville (TYS)
to Charlotte (CLT)
Flights from Knoxville (TYS)
to St Louis (STL)
Flights from Knoxville (TYS)
to Orlando (MCO)
Flights from Knoxville (TYS)
to Honolulu (HNL)
Flights from Knoxville (TYS)
to San Antonio (SAT)
Flights from Knoxville (TYS)
to Omaha (OMA)
Flights from Knoxville (TYS)
to Cancún (CUN)
Flights from Knoxville (TYS)
to Chicago (ORD)
Flights from Knoxville (TYS)
to Portland (PDX)
Flights from Washington (DCA)
to San Antonio (SAT)
Flights from Houston (IAH)
to San Antonio (SAT)
Flights from Newark (EWR)
to San Antonio (SAT)
Flights from Newark (EWR)
to San Antonio (SAT)
Flights from Phoenix (PHX)
to San Antonio (SAT)
Flights from Detroit (DTW)
to San Antonio (SAT)
Flights from San Diego (SAN)
to San Antonio (SAT)
Flights from Orlando (MCO)
to San Antonio (SAT)
Flights from Houston (HOU)
to San Antonio (SAT)
Flights from Milwaukee (MKE)
to San Antonio (SAT)
Flights from Minneapolis (MSP)
to San Antonio (SAT)
Flights from Minneapolis (MSP)
to San Antonio (SAT)
Flights from Dallas (DAL)
to San Antonio (SAT)
Flights from Madison (MSN)
to San Antonio (SAT)
Flights from Fayetteville/Springdale (XNA)
to San Antonio (SAT)
Flights from Denver (DEN)
to San Antonio (SAT)
Flights from Portland (PDX)
to San Antonio (SAT)
Flights from Las Vegas (LAS)
to San Antonio (SAT)
Flights from Ontario (ONT)
to San Antonio (SAT)
Flights from Ontario (ONT)
to San Antonio (SAT)
Cheap flights to North America (NA)
Cheap flights to United States (US)
Cheap flights to Tennessee (US-TN)
Cheap flights to Texas (US-TX)
Cheap flights from North America (NA)
Cheap flights from United States (US)
Cheap flights from Tennessee (US-TN)
Cheap flights from Texas (US-TX)
Flights to San Antonio (SAT)
Flights to Knoxville (TYS)
Flights from San Antonio (SAT)
Flights from San Antonio (SAT)
to Knoxville (TYS)
Flights from Knoxville (TYS)
Why Fareleaders for TYS to SAT Plane Tickets
New Deals Everyday
Get the best prices on TYS to SAT flights—we update our fares daily so you never miss a saving.
No Service Fees
Compare hundreds of Knoxville to San Antonio flights and secure the best deals—we never add any service fees.