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Uncover the best deals on Pensacola to Knoxville flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest PNS - TYS Flights
Useful information for finding best airline tickets from Pensacola Regional to McGhee Tyson on your next trip.
Cheapest Round Trip Flight
$334
Southwest Airlines
• 2 stops
• 17h 35m
Sep 18 – Sep 26
The cheapest round trip flight from Pensacola to Knoxville (PNS-TYS-PNS) is currently $334
Fastest Flight
5h 35m
The fastest nonstop flight from Pensacola to Knoxville (PNS-TYS) takes 5h 35m
Top Airlines Flying from Pensacola to Knoxville
Latest Flight Deals from Pensacola (PNS) to Knoxville (TYS)
Compare and book low fare round-trip air tickets from Pensacola to Knoxville. Ideal for travelers with confirmed return itineraries.
Sep 18 - Sep 26, Economy
Pensacola → Knoxville
17h 35m
6:40 AM - 6:35 PM • 2 stops
Pensacola → Knoxville
5h 10m
6:50 AM - 9:00 AM • 1 stop
Southwest Airlines
Sep 18 - Sep 26, Economy
Pensacola → Knoxville
9h 5m
6:40 AM - 1:25 PM • 1 stop
Pensacola → Knoxville
17h 5m
6:50 AM - 4:15 PM • 2 stops
Southwest Airlines
Sep 18 - Sep 26, Economy
Pensacola → Knoxville
5h 35m
7:45 AM - 12:20 PM • 1 stop
Pensacola → Knoxville
13h 45m
8:50 AM - 4:15 PM • 2 stops
Southwest Airlines
Sep 18 - Sep 26, Economy
Pensacola → Knoxville
15h 50m
7:45 AM - 6:35 PM • 1 stop
Pensacola → Knoxville
15h 55m
7:50 AM - 4:45 PM • 3 stops
Southwest Airlines
Sep 18 - Sep 26, Economy
Pensacola → Knoxville
14h 10m
10:05 AM - 7:55 PM • 3 stops
Pensacola → Knoxville
5h 10m
6:50 AM - 9:00 AM • 1 stop
Southwest Airlines
FAQs on Pensacola to Knoxville Flights
What are the airports in Pensacola?
PNS
What’s the most popular airline flying from PNS to TYS?
The most popular airline flying from Pensacola to Knoxville are
Can I fly from PNS to TYS non-stop?
NO
Which airlines fly nonstop between Pensacola and Knoxville?
The non-stop flights between Pensacola and Knoxville are .
What’s the earliest departure time from PNS to TYS Airport?
The earliest flight leaves PNS at 6:40 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Pensacola to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from PNS to TYS?
Read the fare rules of the Pensacola to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Pensacola and Knoxville?
operate flights between Pensacola and Knoxville
How long does a flight from Pensacola to Knoxville take?
It takes approximately 1 hour to fly non-stop from PNS to TYS, which is 411.71 miles by air.
Which airlines provide the cheapest flights from Pensacola (PNS) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from PNS were found on WN : USD 334
Do I need a passport to fly between PNS and TYS?
No
What’s the latest departure time from PNS to TYS ?
The last flight leaves PNS at 10:05 am
Hotels in Knoxville (TYS)
5 hotels near McGhee Tyson — compare rates from top booking sites.
4-star hotel
Hilton Knoxville Airport
📍 2001 Alcoa Highway, Alcoa, Tennessee 37701-3163
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4-star hotel
Brookstone Lodge
📍 4 Roberts Rd, Asheville, North Carolina 28803
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4-star hotel
Baskins Creek Condos By Wyndham Vacation Rentals
📍 215 Woliss Ln, Gatlinburg, Tennessee 37738
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4-star hotel
Deer Ridge Mountain Resort
📍 3710 Weber Rd., Gatlinburg, Tennessee 37738
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4-star hotel
Christopher Place
📍 1500 Pinnacles Way, Newport, Tennessee 37821
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Hotel Deals in Knoxville (TN)
-20.0%
OYO Rooms
OYO Hotel Knoxville TN Cedar Bluff I-40
6.1/10
★★★☆☆
Hotel
88.0 rooms
✓ Free WiFi
📍 317 N Cedar Bluff Rd, Knoxville (TN), Tennessee
OYO Hotel Knoxville TN Cedar Bluff I-40 provides flawless service and all the necessary facilities for visitors. Stay connected with your associates, as complimentary Wi-Fi is available during your e…
Check-in 03:00 PM · Check-out 11:00 AM
$52/night
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Wyndham Hotels & Resorts
Days Inn by Wyndham Knoxville North
6.2/10
★★★☆☆
Motel, Hotel
80.0 rooms
✓ Free WiFi
✓ Breakfast
📍 114 Dante Rd., Knoxville (TN), Tennessee
Days Inn by Wyndham Knoxville North provides flawless service and all the necessary facilities for visitors.Remain linked during your visit by utilizing the complimentary internet access available.Th…
Check-in 03:00 PM · Check-out 11:00 AM
$56/night
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Wyndham Hotels & Resorts
Super 8 By Wyndham Knoxville East
6.8/10
★★☆☆☆
Hotel
61.0 rooms
✓ Free WiFi
✓ Breakfast
📍 7585 Crosswood Blvd., Knoxville (TN), Tennessee
Great care is taken to ensure guests experience comfort through top-notch services and amenities. Remain linked during your visit by utilizing the complimentary internet access available.The hotel of…
Check-in 04:00 PM · Check-out 11:00 AM
$59/night
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Wyndham Hotels & Resorts
Americas Best Value Inn Knoxville Downtown North
7.5/10
★★☆☆☆
Hotel
105.0 rooms
✓ Free WiFi
📍 341 Merchants Drive, Knoxville (TN), Tennessee
Super 8 By Wyndham Knoxville Downtown Area offers top-notch services and amenities, ensuring guests experience utmost comfort.Share your photos and respond to emails at your convenience, thanks to th…
Check-in 02:00 PM · Check-out 11:00 AM
$59/night
View Deal
Wyndham Hotels & Resorts
Days Inn by Wyndham Knoxville East
7.3/10
★★★☆☆
Hotel
115.0 rooms
✓ Free WiFi
✓ Breakfast
📍 5423 Asheville Highway, Knoxville (TN)
At Days Inn by Wyndham Knoxville East, exceptional service and top-notch amenities create a memorable experience for guests.Complimentary internet access is available in the hotel to ensure you stay …
Check-in 03:00 PM · Check-out 11:00 AM
$60/night
View Deal
Red Roof Inn
Red Roof Inn & Suites Knoxville East
7.8/10
★★☆☆☆
Hotel
54.0 rooms
✓ Free WiFi
📍 7525 Crosswood Boulevard, Knoxville (TN)
Great care is taken to ensure guests experience comfort through top-notch services and amenities. Remain linked during your visit by utilizing the complimentary internet access available. The hotel o…
Check-in 02:00 PM · Check-out 12:00 PM
$60/night
View Deal
Wyndham Hotels & Resorts
Baymont by Wyndham Knoxville I-75
7.0/10
★★★☆☆
Hotel
116.0 rooms
✓ Free WiFi
✓ Breakfast
📍 6712 Central Avenue Pike, Knoxville (TN)
At Baymont by Wyndham Knoxville I-75, exceptional service and top-notch amenities create a memorable experience for guests.Complimentary internet access is available in the hotel to ensure you stay c…
Check-in 03:00 PM · Check-out 11:00 AM
$61/night
View Deal
Choice Hotels
Quality Inn Merchants Drive
6.8/10
★★★☆☆
Hotel
126.0 rooms
✓ Free WiFi
✓ Breakfast
📍 117 Cedar Lane, Knoxville (TN), Tennessee
At Quality Inn Merchants Drive, exceptional service and top-notch amenities create a memorable experience for guests. Complimentary internet access is available in the hotel to ensure you stay connec…
Check-in 03:00 PM · Check-out 11:00 AM
$61/night
View Deal
Wyndham Hotels & Resorts
Days Inn by Wyndham Knoxville West
6.1/10
★★☆☆☆
Hotel
106.0 rooms
✓ Free WiFi
✓ Breakfast
📍 9240 Parkwest Blvd., Knoxville (TN), Tennessee
Experience an abundance of unparalleled facilities and features at Days Inn by Wyndham Knoxville West. Share your photos and respond to emails at your convenience, thanks to the free Wi-Fi internet a…
Check-in 02:00 PM · Check-out 11:00 AM
$63/night
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Pensacola (PNS) to Knoxville (TYS): Airport Information
| Origin Airport | Pensacola Regional , Pensacola, US |
| Destination Airport | McGhee Tyson , Knoxville, US |
| Distance | 412 miles |
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