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Uncover the best deals on Knoxville to Houston flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest TYS - IAH Flights
Useful information for finding best airline tickets from McGhee Tyson to George Bush Intercontinental Houston on your next trip.
Cheapest Round Trip Flight
$573
American Airlines
• 1 stop
• 10h 25m
Nov 02 – Nov 09
The cheapest round trip flight from Knoxville to Houston (TYS-IAH-TYS) is currently $573
Cheapest Direct Flight
$300
United Airlines
• nonstop
• 3h 56m
Nov 25
The cheapest nonstop flight from Knoxville to Houston (TYS-IAH) is currently $300
Fastest Flight
3h 56m
The fastest nonstop flight from Knoxville to Houston (TYS-IAH) takes 3h 56m
Top Airlines Flying from Knoxville to Houston
Latest Flight Deals from Knoxville (TYS) to Houston (IAH)
Compare and book low fare round-trip air tickets from Knoxville to Houston. Ideal for travelers with confirmed return itineraries.
Nov 02 - Nov 09, Economy
Knoxville → Houston
10h 25m
5:19 PM - 10:44 PM • 1 stop
Knoxville → Houston
8h 39m
9:04 AM - 3:23 PM • 1 stop
American Airlines
Nov 02 - Nov 09, Economy
Knoxville → Houston
9h 19m
11:36 AM - 4:35 PM • 1 stop
Knoxville → Houston
8h 39m
9:04 AM - 3:23 PM • 1 stop
American Airlines
Nov 02 - Nov 09, Economy
Knoxville → Houston
10h 49m
5:05 PM - 10:54 PM • 1 stop
Knoxville → Houston
10h 14m
1:40 PM - 8:54 PM • 1 stop
United Airlines
Nov 02 - Nov 09, Economy
Knoxville → Houston
12h 15m
1:55 PM - 8:30 PM • 1 stop
Knoxville → Houston
3h 34m
2:40 PM - 5:54 PM • nonstop
United Airlines
Nov 02 - Nov 09, Economy
Knoxville → Houston
3h 56m
11:59 AM - 1:35 PM • nonstop
Knoxville → Houston
10h 14m
1:40 PM - 8:54 PM • 1 stop
United Airlines
Flying to Houston soon? We've surfaced some of the most affordable last-minute flights from Knoxville to Houston, ideal for urgent plans or spontaneous trips.
Nov 02 - Nov 09, Economy
Knoxville → Houston
10h 25m
5:19 PM - 10:44 PM • 1 stop
Knoxville → Houston
8h 39m
9:04 AM - 3:23 PM • 1 stop
American Airlines
Nov 02 - Nov 09, Economy
Knoxville → Houston
9h 19m
11:36 AM - 4:35 PM • 1 stop
Knoxville → Houston
8h 39m
9:04 AM - 3:23 PM • 1 stop
American Airlines
Nov 02 - Nov 09, Economy
Knoxville → Houston
10h 49m
5:05 PM - 10:54 PM • 1 stop
Knoxville → Houston
10h 14m
1:40 PM - 8:54 PM • 1 stop
United Airlines
Nov 02 - Nov 09, Economy
Knoxville → Houston
12h 15m
1:55 PM - 8:30 PM • 1 stop
Knoxville → Houston
3h 34m
2:40 PM - 5:54 PM • nonstop
United Airlines
Nov 02 - Nov 09, Economy
Knoxville → Houston
3h 56m
11:59 AM - 1:35 PM • nonstop
Knoxville → Houston
10h 14m
1:40 PM - 8:54 PM • 1 stop
United Airlines
Looking for the fastest way to Houston? These direct flight options from TYS to IAH offer both convenience and value—no layovers, just straight to your destination.
Nov 25 - Dec 02, Economy
Knoxville → Houston
3h 56m
11:59 AM - 1:35 PM • nonstop
Knoxville → Houston
3h 33m
3:05 PM - 6:18 PM • nonstop
United Airlines
Nov 25 - Dec 02, Economy
Knoxville → Houston
4h
7:00 AM - 8:40 AM • nonstop
Knoxville → Houston
3h 32m
8:00 AM - 11:12 AM • nonstop
United Airlines
Nov 25 - Dec 02, Economy
Knoxville → Houston
3h 57m
3:45 PM - 5:22 PM • nonstop
Knoxville → Houston
3h 33m
3:05 PM - 6:18 PM • nonstop
United Airlines
Nov 02 - Nov 09, Economy
Knoxville → Houston
4h
7:00 AM - 8:40 AM • nonstop
Knoxville → Houston
3h 37m
6:40 PM - 9:57 PM • nonstop
United Airlines
Nov 02 - Nov 09, Economy
Knoxville → Houston
3h 57m
3:45 PM - 5:22 PM • nonstop
Knoxville → Houston
3h 34m
2:40 PM - 5:54 PM • nonstop
United Airlines
FAQs on Knoxville to Houston Flights
What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to IAH?
The most popular airline flying from Knoxville to Houston are
Can I fly from TYS to IAH non-stop?
Yes, you can fly TYS to IAH non-stop on
Which airlines fly nonstop between Knoxville and Houston?
The non-stop flights between Knoxville and Houston are .
What’s the earliest departure time from TYS to IAH Airport?
The earliest flight leaves TYS at 7:00 am and lands in IAH - George Bush Intercontinental Houston
What are the airports in Houston?
IAH
Can I make changes to my Knoxville to Houston flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to IAH?
Read the fare rules of the Knoxville to Houston air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Houston?
operate flights between Knoxville and Houston
How long does a flight from Knoxville to Houston take?
It takes approximately 2 hour to fly non-stop from TYS to IAH, which is 771.46 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Houston (IAH) ?
In the past couple of days, the cheapest tickets to IAH from TYS were found on UA : USD 833
Do I need a passport to fly between TYS and IAH?
No
What’s the latest departure time from TYS to IAH ?
The last flight leaves TYS at 5:19 pm
Hotels in Houston (IAH)
5 hotels near George Bush Intercontinental Houston — compare rates from top booking sites.
5-star hotel
Four Seasons Hotel Houston
📍 1300 Lamar St, Houston, Texas 77010
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5-star hotel
Hotel Granduca Houston
📍 1080 Uptown Park Blvd, Houston, Texas 77056
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5-star hotel
JW Marriott Hotel by the Galleria
📍 5150 Westheimer Rd, Houston, Texas 77056
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4-star hotel
Hotel Sorella City Centre
📍 800 Sorella Court, Houston, Texas 77024
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4-star hotel
Hotel ZaZa Houston
📍 5701 Main Street, Houston, Texas 77005
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Search Deals →
Hotel Deals in Houston (TX)
Wyndham Hotels & Resorts
Ramada by Wyndham Houston Intercontinental Airport East
7.6/10
★★★★☆
Hotel
170.0 rooms
✓ Free WiFi
📍 6115 Will Clayton Parkway, Houston (TX), Texas
Ramada by Wyndham Houston Intercontinental Airport East offers top-notch services and amenities, ensuring guests experience utmost comfort. Share your photos and respond to emails at your convenience…
Check-in 03:00 PM · Check-out 11:00 AM
$51/night
View Deal
Wyndham Hotels & Resorts
Wingate by Wyndham Humble Houston Intercontinental Airport
7.5/10
★★★★☆
Hotel
78.0 rooms
✓ Free WiFi
✓ Breakfast
📍 7114 Will Clayton Pkwy, Houston (TX), Texas
Experience an abundance of unparalleled facilities and features at Wingate by Wyndham Humble Houston Intercontinental Airport.Maintain seamless communication using the complimentary Wi-Fi at hotel. E…
Check-in 02:00 PM · Check-out 11:00 AM
$51/night
View Deal
West U Studio, Near Med Center, Stadiums & Zoo
10.0/10
★★★★☆
✓ Free WiFi
$54/night
View Deal
Choice Hotels
Comfort Suites near Westchase on Beltway 8
7.4/10
★★★☆☆
Hotel
74.0 rooms
✓ Free WiFi
✓ Breakfast
📍 7707 West Sam Houston Pkwy S, Houston (TX), Texas
Great care is taken to ensure guests experience comfort through top-notch services and amenities.Stay connected with your associates, as complimentary Wi-Fi is available during your entire visit.When…
Check-in 03:00 PM · Check-out 11:00 AM
$66/night
View Deal
Heritage Place Houston Brookhollow
8.5/10
★★★☆☆
✓ Free WiFi
$70/night
View Deal
InterContinental Hotels Group
Crowne Plaza Houston Med Ctr-Galleria Area by IHG
7.9/10
★★★★☆
Hotel
354.0 rooms
✓ Free WiFi
✓ Breakfast
📍 2712 Southwest Freeway, Houston (TX), Texas
Crowne Plaza Houston Med Ctr-Galleria Area By IHG provides flawless service and all the necessary facilities for visitors. Remain linked during your visit by utilizing the complimentary internet acce…
Check-in 04:00 PM · Check-out 11:00 AM
$71/night
View Deal
Extended Stay America
Extended Stay America Suites - Houston - Med. Ctr. - NRG Park - Braeswood Blvd.
7.4/10
★★★☆☆
Hotel
126.0 rooms
✓ Free WiFi
✓ Breakfast
📍 1301 Braeswood Blvd, Houston (TX), Texas
Extended Stay America Suites - Houston - Med. Ctr. - NRG Park - Braeswood Blvd. offers top-notch services and amenities, ensuring guests experience utmost comfort. Remain linked during your visit by …
Check-in 03:00 PM · Check-out 11:00 AM
$82/night
View Deal
Marriott
Courtyard by Marriott Houston I-10 West/Park Row
8.6/10
★★★☆☆
Hotel
✓ Breakfast
📍 18010 Park Row Drive, Houston (TX)
Great care is taken to ensure guests experience comfort through top-notch services and amenities. When arriving by car, take advantage of the hotel's convenient on-site parking facilities. Whether it…
Check-in 03:00 PM · Check-out 12:00 PM
$84/night
View Deal
No chain
Champions Club and Hotel Houston Westchase
8.6/10
★★★★☆
Hotel
64.0 rooms
✓ Free WiFi
📍 6440 West Sam Houston Parkway South, Houston (TX), Texas
Check-in 3:00 PM · Check-out 11:00 AM
$85/night
View Deal
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Knoxville (TYS) to Houston (IAH): Airport Information
| Origin Airport | McGhee Tyson , Knoxville, US |
| Destination Airport | George Bush Intercontinental Houston , Houston, US |
| Distance | 771 miles |
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