Cheap Flight Tickets from Knoxville (TYS) to Houston (HOU), Starting at $157

Good to Know: Cheapest and Fastest TYS - HOU Flights

Useful information for finding best airline tickets from McGhee Tyson to William P Hobby on your next trip.

Cheapest Round Trip Flight

$265

DL Delta Airlines • 1 stop • 8h 25m

Jul 29 – Aug 01

The cheapest round trip flight from Knoxville to Houston (TYS-HOU-TYS) is currently $265

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Cheapest Direct Flight

$157

UA United Airlines • nonstop • 3h 49m

Oct 07

The cheapest nonstop flight from Knoxville to Houston (TYS-HOU) is currently $157

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Fastest Flight

3h 45m

The fastest nonstop flight from Knoxville to Houston (TYS-HOU) takes 3h 45m

Top Airlines Flying from Knoxville to Houston

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Knoxville (TYS) to Houston (HOU)

Compare and book low fare round-trip air tickets from Knoxville to Houston. Ideal for travelers with confirmed return itineraries.

Jul 29 - Aug 01, Economy
DL
Knoxville → Houston
8h 25m
5:40 AM - 9:45 AM • 1 stop
DL
Knoxville → Houston
8h 44m
5:20 PM - 11:44 PM • 1 stop
$265
Delta Airlines
Jul 29 - Aug 01, Economy
WN
Knoxville → Houston
17h 5m
7:10 AM - 4:35 PM • 1 stop
WN
Knoxville → Houston
9h 10m
11:30 AM - 6:20 PM • 1 stop
$328
Southwest Airlines
Jul 29 - Aug 01, Economy
DL
Knoxville → Houston
19h 2m
5:40 AM - 4:22 PM • 1 stop
DL
Knoxville → Houston
8h 44m
5:20 PM - 11:44 PM • 1 stop
$395
Delta Airlines
Jul 29 - Aug 01, Economy
DL
Knoxville → Houston
12h 10m
5:40 AM - 12:10 PM • 1 stop
DL
Knoxville → Houston
8h 44m
5:20 PM - 11:44 PM • 1 stop
$395
Delta Airlines
Jul 29 - Aug 01, Economy
DL
Knoxville → Houston
15h 47m
7:35 AM - 4:22 PM • 1 stop
DL
Knoxville → Houston
8h 44m
5:20 PM - 11:44 PM • 1 stop
$395
Delta Airlines
Jul 29 - Aug 01, Economy
DL
Knoxville → Houston
10h 57m
3:54 PM - 9:51 PM • 1 stop
DL
Knoxville → Houston
8h 44m
5:20 PM - 11:44 PM • 1 stop
$464
Delta Airlines

Fly from Knoxville to Houston with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Knoxville to Houston? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Knoxville to Houston Flights

What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to HOU?
The most popular airline flying from Knoxville to Houston are
Can I fly from TYS to HOU non-stop?
Yes, you can fly TYS to HOU non-stop on
Which airlines fly nonstop between Knoxville and Houston?
The non-stop flights between Knoxville and Houston are .
What’s the earliest departure time from TYS to HOU Airport?
The earliest flight leaves TYS at 5:40 am and lands in HOU - William P Hobby
What are the airports in Houston?
HOU
Can I make changes to my Knoxville to Houston flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to HOU?
Read the fare rules of the Knoxville to Houston air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Houston?
operate flights between Knoxville and Houston
How long does a flight from Knoxville to Houston take?
It takes approximately 2 hour to fly non-stop from TYS to HOU, which is 781.81 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Houston (HOU) ?
In the past couple of days, the cheapest tickets to HOU from TYS were found on WN : USD 328
Do I need a passport to fly between TYS and HOU?
No
What’s the latest departure time from TYS to HOU ?
The last flight leaves TYS at 3:54 pm

Knoxville (TYS) to Houston (HOU): Airport Information

Origin Airport McGhee Tyson , Knoxville, US
Destination Airport William P Hobby , Houston, US
Distance 782 miles

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