Cheap Flight Tickets from Knoxville (TYS) to Chicago (MDW), Starting at $232

Good to Know: Cheapest and Fastest TYS - MDW Flights

Useful information for finding best airline tickets from McGhee Tyson to Chicago Midway International on your next trip.

Cheapest Round Trip Flight

$232

WN Southwest Airlines • 1 stop • 16h 55m

Jun 30 – Aug 07

The cheapest round trip flight from Knoxville to Chicago (TYS-MDW-TYS) is currently $232

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Cheapest Direct Flight

$325

UA United Airlines • nonstop • 2h 39m

Jun 30

The cheapest nonstop flight from Knoxville to Chicago (TYS-MDW) is currently $325

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Fastest Flight

2h 39m

The fastest nonstop flight from Knoxville to Chicago (TYS-MDW) takes 2h 39m

Latest Flight Deals from Knoxville (TYS) to Chicago (MDW)

Compare and book low fare round-trip air tickets from Knoxville to Chicago. Ideal for travelers with confirmed return itineraries.

Jun 30 - Aug 07, Economy
WN
Knoxville → Chicago
16h 55m
12:45 PM - 10:00 PM • 1 stop
WN
Knoxville → Chicago
5h 20m
8:00 AM - 12:20 PM • 1 stop
$232
Southwest Airlines
Jun 30 - Aug 07, Economy
DL
Knoxville → Chicago
7h 25m
11:55 AM - 3:40 PM • 1 stop
DL
Knoxville → Chicago
5h 36m
10:54 AM - 3:30 PM • 1 stop
$248
Delta Airlines
Jul 01 - Aug 08, Economy
DL
Knoxville → Chicago
5h 55m
3:36 PM - 6:31 PM • 1 stop
DL
Knoxville → Chicago
8h 20m
4:39 PM - 10:39 PM • 1 stop
$338
Delta Airlines
Jul 01 - Aug 08, Economy
DL
Knoxville → Chicago
8h 49m
5:40 AM - 10:09 AM • 1 stop
DL
Knoxville → Chicago
8h 20m
4:39 PM - 10:39 PM • 1 stop
$573
Delta Airlines
Jul 01 - Aug 08, Economy
DL
Knoxville → Chicago
13h 25m
8:35 AM - 3:40 PM • 1 stop
DL
Knoxville → Chicago
8h 20m
4:39 PM - 10:39 PM • 1 stop
$641
Delta Airlines
Jul 01 - Aug 08, Economy
DL
Knoxville → Chicago
17h 36m
8:35 AM - 6:31 PM • 2 stops
DL
Knoxville → Chicago
8h 20m
4:39 PM - 10:39 PM • 1 stop
$690
Delta Airlines

Fly from Knoxville to Chicago with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Knoxville to Chicago? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Knoxville to Chicago Flights

What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to MDW?
The most popular airline flying from Knoxville to Chicago are
Can I fly from TYS to MDW non-stop?
Yes, you can fly TYS to MDW non-stop on
Which airlines fly nonstop between Knoxville and Chicago?
The non-stop flights between Knoxville and Chicago are .
What’s the earliest departure time from TYS to MDW Airport?
The earliest flight leaves TYS at 5:40 am and lands in MDW - Chicago Midway International
What are the airports in Chicago?
ORD,MDW
Can I make changes to my Knoxville to Chicago flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to MDW?
Read the fare rules of the Knoxville to Chicago air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Chicago?
operate flights between Knoxville and Chicago
How long does a flight from Knoxville to Chicago take?
It takes approximately 2 hour to fly non-stop from TYS to MDW, which is 459.25 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Chicago (MDW) ?
In the past couple of days, the cheapest tickets to MDW from TYS were found on DL : USD 573
Do I need a passport to fly between TYS and MDW?
No
What’s the latest departure time from TYS to MDW ?
The last flight leaves TYS at 6:43 pm

Knoxville (TYS) to Chicago (MDW): Airport Information

Origin Airport McGhee Tyson , Knoxville, US
Destination Airport Chicago Midway International , Chicago, US
Distance 459 miles

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