Cheap Flight Tickets from Knoxville (TYS) to Chicago (MDW), Starting at $413

Good to Know: Cheapest and Fastest TYS - MDW Flights

Useful information for finding best airline tickets from McGhee Tyson to Chicago Midway International on your next trip.

Cheapest Round Trip Flight

$413

WN Southwest Airlines • 1 stop • 8h 50m

Oct 08 – Oct 11

The cheapest round trip flight from Knoxville to Chicago (TYS-MDW-TYS) is currently $413

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Fastest Flight

5h 48m

The fastest nonstop flight from Knoxville to Chicago (TYS-MDW) takes 5h 48m

Latest Flight Deals from Knoxville (TYS) to Chicago (MDW)

Compare and book low fare round-trip air tickets from Knoxville to Chicago. Ideal for travelers with confirmed return itineraries.

Oct 08 - Oct 11, Economy
WN
Knoxville → Chicago
8h 50m
7:25 PM - 11:55 PM • 1 stop
WN
Knoxville → Chicago
8h 40m
11:00 AM - 5:20 PM • 1 stop
$413
Southwest Airlines
Oct 08 - Oct 11, Economy
WN
Knoxville → Chicago
12h 15m
8:20 AM - 2:55 PM • 2 stops
WN
Knoxville → Chicago
7h 25m
5:00 PM - 10:45 PM • 1 stop
$419
Southwest Airlines
Oct 08 - Oct 11, Economy
WN
Knoxville → Chicago
10h 30m
8:20 AM - 1:50 PM • 2 stops
WN
Knoxville → Chicago
8h 40m
11:00 AM - 5:20 PM • 1 stop
$419
Southwest Airlines
Oct 08 - Oct 11, Economy
WN
Knoxville → Chicago
8h 45m
8:20 AM - 12:45 PM • 2 stops
WN
Knoxville → Chicago
5h 15m
7:55 AM - 12:10 PM • 1 stop
$419
Southwest Airlines
Oct 08 - Oct 11, Economy
DL
Knoxville → Chicago
5h 54m
7:09 AM - 10:03 AM • 1 stop
DL
Knoxville → Chicago
5h 50m
6:04 AM - 10:54 AM • 1 stop
$458
Delta Airlines
Oct 08 - Oct 11, Economy
DL
Knoxville → Chicago
5h 48m
7:45 PM - 10:33 PM • 1 stop
DL
Knoxville → Chicago
7h 7m
5:27 AM - 10:54 AM • 1 stop
$458
Delta Airlines

Fly from Knoxville to Chicago with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Knoxville to Chicago? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Knoxville to Chicago Flights

What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to MDW?
The most popular airline flying from Knoxville to Chicago are
Can I fly from TYS to MDW non-stop?
NO
Which airlines fly nonstop between Knoxville and Chicago?
The non-stop flights between Knoxville and Chicago are .
What’s the earliest departure time from TYS to MDW Airport?
The earliest flight leaves TYS at 7:09 am and lands in MDW - Chicago Midway International
What are the airports in Chicago?
ORD,MDW
Can I make changes to my Knoxville to Chicago flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to MDW?
Read the fare rules of the Knoxville to Chicago air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Chicago?
operate flights between Knoxville and Chicago
How long does a flight from Knoxville to Chicago take?
It takes approximately 2 hour to fly non-stop from TYS to MDW, which is 459.25 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Chicago (MDW) ?
In the past couple of days, the cheapest tickets to MDW from TYS were found on DL : USD 458
Do I need a passport to fly between TYS and MDW?
No
What’s the latest departure time from TYS to MDW ?
The last flight leaves TYS at 7:45 pm

Knoxville (TYS) to Chicago (MDW): Airport Information

Origin Airport McGhee Tyson , Knoxville, US
Destination Airport Chicago Midway International , Chicago, US
Distance 459 miles

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