Cheap Flight Tickets from Knoxville (TYS) to Santa Ana (SNA), Starting at $309

Good to Know: Cheapest and Fastest TYS - SNA Flights

Useful information for finding best airline tickets from McGhee Tyson to John Wayne -Orange County on your next trip.

Cheapest Round Trip Flight

$309

AA American Airlines • 1 stop • 13h 27m

Sep 21 – Sep 25

The cheapest round trip flight from Knoxville to Santa Ana (TYS-SNA-TYS) is currently $309

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Fastest Flight

13h 25m

The fastest nonstop flight from Knoxville to Santa Ana (TYS-SNA) takes 13h 25m

Top Airlines Flying from Knoxville to Santa Ana

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

American Airlines, AA

American Airlines

United Airlines, UA

United Airlines

Latest Flight Deals from Knoxville (TYS) to Santa Ana (SNA)

Compare and book low fare round-trip air tickets from Knoxville to Santa Ana. Ideal for travelers with confirmed return itineraries.

Sep 21 - Sep 25, Economy
AA
Knoxville → Santa Ana
13h 27m
2:43 PM - 7:50 PM • 1 stop
AA
Knoxville → Santa Ana
11h 57m
10:35 AM - 8:52 PM • 1 stop
$309
American Airlines
Sep 21 - Sep 25, Economy
WN
Knoxville → Santa Ana
21h 55m
7:10 AM - 5:25 PM • 2 stops
WN
Knoxville → Santa Ana
10h 10m
6:45 AM - 3:55 PM • 1 stop
$592
Southwest Airlines
Sep 21 - Sep 25, Economy
WN
Knoxville → Santa Ana
15h 25m
7:10 AM - 1:35 PM • 2 stops
WN
Knoxville → Santa Ana
10h 50m
11:05 AM - 8:55 PM • 1 stop
$592
Southwest Airlines
Sep 21 - Sep 25, Economy
WN
Knoxville → Santa Ana
13h 25m
4:50 PM - 9:55 PM • 1 stop
WN
Knoxville → Santa Ana
15h 25m
6:45 AM - 7:10 PM • 3 stops
$597
Southwest Airlines
Sep 21 - Sep 25, Economy
DL
Knoxville → Santa Ana
15h 24m
6:30 AM - 12:54 PM • 1 stop
DL
Knoxville → Santa Ana
12h 4m
12:50 PM - 11:14 PM • 1 stop
$606
Delta Airlines
Sep 21 - Sep 25, Economy
DL
Knoxville → Santa Ana
15h 6m
12:23 PM - 6:29 PM • 1 stop
DL
Knoxville → Santa Ana
27h 8m
9:15 PM - 4:43 PM • 2 stops
$1253
Delta Airlines

Fly from Knoxville to Santa Ana with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Knoxville to Santa Ana? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Knoxville to Santa Ana Flights

What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to SNA?
The most popular airline flying from Knoxville to Santa Ana are
Can I fly from TYS to SNA non-stop?
NO
Which airlines fly nonstop between Knoxville and Santa Ana?
The non-stop flights between Knoxville and Santa Ana are .
What’s the earliest departure time from TYS to SNA Airport?
The earliest flight leaves TYS at 6:30 am and lands in SNA - John Wayne -Orange County
What are the airports in Santa Ana?
SNA
Can I make changes to my Knoxville to Santa Ana flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to SNA?
Read the fare rules of the Knoxville to Santa Ana air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Santa Ana?
operate flights between Knoxville and Santa Ana
How long does a flight from Knoxville to Santa Ana take?
It takes approximately 4 hour to fly non-stop from TYS to SNA, which is 1923.48 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Santa Ana (SNA) ?
In the past couple of days, the cheapest tickets to SNA from TYS were found on DL : USD 1253
Do I need a passport to fly between TYS and SNA?
No
What’s the latest departure time from TYS to SNA ?
The last flight leaves TYS at 4:50 pm

Knoxville (TYS) to Santa Ana (SNA): Airport Information

Origin Airport McGhee Tyson , Knoxville, US
Destination Airport John Wayne -Orange County , Santa Ana, US
Distance 1923 miles

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