Cheap Flight Tickets from Detroit (DTW) to Knoxville (TYS), Starting at $150

Good to Know: Cheapest and Fastest DTW - TYS Flights

Useful information for finding best airline tickets from Detroit Metropolitan Wayne County to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$233

WN Southwest Airlines • 1 stop • 10h 5m

Aug 27 – Aug 27

The cheapest round trip flight from Detroit to Knoxville (DTW-TYS-DTW) is currently $233

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Cheapest Direct Flight

$150

DL Delta Airlines • nonstop • 40m

Aug 26

The cheapest nonstop flight from Detroit to Knoxville (DTW-TYS) is currently $150

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Fastest Flight

39m

The fastest nonstop flight from Detroit to Knoxville (DTW-TYS) takes 39m

Top Airlines Flying from Detroit to Knoxville

Southwest Airlines-WN

Southwest Airlines

United Airlines, UA

United Airlines

Delta Airline, DL

Delta Airlines

WestJet Airlines

WestJet Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Detroit (DTW) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Detroit to Knoxville. Ideal for travelers with confirmed return itineraries.

Aug 27 - Aug 27, Economy
WN
Detroit → Knoxville
10h 5m
5:55 AM - 12:00 PM • 1 stop
WN
Detroit → Knoxville
7h 30m
5:45 PM - 10:35 PM • 1 stop
$233
Southwest Airlines
Aug 27 - Aug 31, Economy
UA
Detroit → Knoxville
10h 28m
10:30 AM - 4:58 PM • 1 stop
UA
Detroit → Knoxville
7h 3m
6:02 PM - 10:25 PM • 1 stop
$598
United Airlines
Aug 27 - Aug 31, Economy
UA
Detroit → Knoxville
7h 3m
12:35 PM - 4:58 PM • 1 stop
UA
Detroit → Knoxville
7h 29m
10:40 AM - 3:29 PM • 1 stop
$598
United Airlines
Aug 27 - Aug 31, Economy
UA
Detroit → Knoxville
6h 57m
10:20 AM - 2:37 PM • 1 stop
UA
Detroit → Knoxville
10h 25m
7:00 AM - 1:25 PM • 1 stop
$598
United Airlines
Aug 27 - Aug 31, Economy
UA
Detroit → Knoxville
7h 17m
6:00 AM - 10:37 AM • 1 stop
UA
Detroit → Knoxville
9h 17m
6:02 PM - 11:59 PM • 1 stop
$598
United Airlines
Aug 26 - Aug 30, Economy
WS
Detroit → Knoxville
28h 48m
9:39 PM - 3:07 PM • 2 stops
G4
Detroit → Knoxville
13h 39m
9:30 AM - 5:49 PM • 1 stop
$2158
WestJet Airlines

Fly from Detroit to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Detroit to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Detroit to Knoxville Flights

What are the airports in Detroit?
DTW
What’s the most popular airline flying from DTW to TYS?
The most popular airline flying from Detroit to Knoxville are
Can I fly from DTW to TYS non-stop?
Yes, you can fly DTW to TYS non-stop on
Which airlines fly nonstop between Detroit and Knoxville?
The non-stop flights between Detroit and Knoxville are .
What’s the earliest departure time from DTW to TYS Airport?
The earliest flight leaves DTW at 5:55 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Detroit to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from DTW to TYS?
Read the fare rules of the Detroit to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Detroit and Knoxville?
operate flights between Detroit and Knoxville
How long does a flight from Detroit to Knoxville take?
It takes approximately 1 hour to fly non-stop from DTW to TYS, which is 442.92 miles by air.
Which airlines provide the cheapest flights from Detroit (DTW) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from DTW were found on WN : USD 233
Do I need a passport to fly between DTW and TYS?
No
What’s the latest departure time from DTW to TYS ?
The last flight leaves DTW at 7:5500 pm

Detroit (DTW) to Knoxville (TYS): Airport Information

Origin Airport Detroit Metropolitan Wayne County , Detroit, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 443 miles

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