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Uncover the best deals on Knoxville to New Orleans flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest TYS - MSY Flights
Useful information for finding best airline tickets from McGhee Tyson to Louis Armstrong New Orleans International on your next trip.
Cheapest Round Trip Flight
$219
Southwest Airlines
• 1 stop
• 12h 25m
Oct 25 – Oct 29
The cheapest round trip flight from Knoxville to New Orleans (TYS-MSY-TYS) is currently $219
Cheapest One way Flight
$60
Southwest Airlines
• 1 stop
• 6h 45m
Oct 25
The cheapest one way flight from Knoxville to New Orleans (TYS-MSY) is currently $60
Fastest Flight
6h 45m
The fastest nonstop flight from Knoxville to New Orleans (TYS-MSY) takes 6h 45m
Top Airlines Flying from Knoxville to New Orleans
Latest Flight Deals from Knoxville (TYS) to New Orleans (MSY)
Compare and book low fare round-trip air tickets from Knoxville to New Orleans. Ideal for travelers with confirmed return itineraries.
Oct 25 - Oct 29, Economy
Knoxville → New Orleans
12h 25m
4:15 PM - 11:00 PM • 1 stop
Knoxville → New Orleans
11h 50m
5:00 AM - 1:10 PM • 1 stop
Southwest Airlines
Oct 25 - Oct 25, Economy
Knoxville → New Orleans
6h 45m
6:25 AM - 9:30 AM • 1 stop
Knoxville → New Orleans
42h 5m
8:20 PM - 10:45 PM • 2 stops
Southwest Airlines
Oct 25 - Oct 25, Economy
Knoxville → New Orleans
8h 25m
7:00 AM - 11:05 AM • 1 stop
Knoxville → New Orleans
26h 58m
5:26 PM - 10:44 AM • 2 stops
United Airlines
Oct 25 - Oct 25, Economy
Knoxville → New Orleans
8h 50m
5:45 AM - 10:15 AM • 1 stop
Knoxville → New Orleans
26h 58m
5:26 PM - 10:44 AM • 2 stops
United Airlines
Oct 25 - Oct 25, Economy
Knoxville → New Orleans
7h 24m
12:06 PM - 3:50 PM • 1 stop
Knoxville → New Orleans
7h 37m
6:02 PM - 11:59 PM • 1 stop
Delta Airlines
Explore competitive one-way airfare options for TYS - MSY flights. Best suited for flexible or open-ended travel plans.
Flying to New Orleans soon? We've surfaced some of the most affordable last-minute flights from Knoxville to New Orleans, ideal for urgent plans or spontaneous trips.
Oct 25 - Oct 29, Economy
Knoxville → New Orleans
12h 25m
4:15 PM - 11:00 PM • 1 stop
Knoxville → New Orleans
11h 50m
5:00 AM - 1:10 PM • 1 stop
Southwest Airlines
Oct 25 - Oct 25, Economy
Knoxville → New Orleans
6h 45m
6:25 AM - 9:30 AM • 1 stop
Knoxville → New Orleans
42h 5m
8:20 PM - 10:45 PM • 2 stops
Southwest Airlines
Oct 25 - Oct 25, Economy
Knoxville → New Orleans
8h 25m
7:00 AM - 11:05 AM • 1 stop
Knoxville → New Orleans
26h 58m
5:26 PM - 10:44 AM • 2 stops
United Airlines
Oct 25 - Oct 25, Economy
Knoxville → New Orleans
8h 50m
5:45 AM - 10:15 AM • 1 stop
Knoxville → New Orleans
26h 58m
5:26 PM - 10:44 AM • 2 stops
United Airlines
Oct 25 - Oct 25, Economy
Knoxville → New Orleans
7h 24m
12:06 PM - 3:50 PM • 1 stop
Knoxville → New Orleans
7h 37m
6:02 PM - 11:59 PM • 1 stop
Delta Airlines
FAQs on Knoxville to New Orleans Flights
What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to MSY?
The most popular airline flying from Knoxville to New Orleans are
Can I fly from TYS to MSY non-stop?
NO
Which airlines fly nonstop between Knoxville and New Orleans?
The non-stop flights between Knoxville and New Orleans are .
What’s the earliest departure time from TYS to MSY Airport?
The earliest flight leaves TYS at 5:45 am and lands in MSY - Louis Armstrong New Orleans International
What are the airports in New Orleans?
MSY
Can I make changes to my Knoxville to New Orleans flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to MSY?
Read the fare rules of the Knoxville to New Orleans air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and New Orleans?
operate flights between Knoxville and New Orleans
How long does a flight from Knoxville to New Orleans take?
It takes approximately 2 hour to fly non-stop from TYS to MSY, which is 541.32 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to New Orleans (MSY) ?
In the past couple of days, the cheapest tickets to MSY from TYS were found on WN : USD 97
Do I need a passport to fly between TYS and MSY?
No
What’s the latest departure time from TYS to MSY ?
The last flight leaves TYS at 7:40 pm
Knoxville (TYS) to New Orleans (MSY): Airport Information
| Origin Airport | McGhee Tyson , Knoxville, US |
| Destination Airport | Louis Armstrong New Orleans International , New Orleans, US |
| Distance | 541 miles |
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