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Uncover the best deals on Knoxville to San Diego flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest TYS - SAN Flights
Useful information for finding best airline tickets from McGhee Tyson to San Diego International on your next trip.
Cheapest Round Trip Flight
$244
Southwest Airlines
• 1 stop
• 13h 20m
Sep 01 – Sep 08
The cheapest round trip flight from Knoxville to San Diego (TYS-SAN-TYS) is currently $244
Fastest Flight
10h 26m
The fastest nonstop flight from Knoxville to San Diego (TYS-SAN) takes 10h 26m
Top Airlines Flying from Knoxville to San Diego
Latest Flight Deals from Knoxville (TYS) to San Diego (SAN)
Compare and book low fare round-trip air tickets from Knoxville to San Diego. Ideal for travelers with confirmed return itineraries.
Sep 01 - Sep 08, Economy
Knoxville → San Diego
13h 20m
1:55 PM - 6:55 PM • 1 stop
Knoxville → San Diego
10h 45m
6:45 AM - 4:30 PM • 1 stop
Southwest Airlines
Sep 01 - Sep 08, Economy
Knoxville → San Diego
15h
7:00 AM - 1:00 PM • 2 stops
Knoxville → San Diego
10h 45m
6:45 AM - 4:30 PM • 1 stop
Southwest Airlines
Sep 01 - Sep 08, Economy
Knoxville → San Diego
16h 40m
1:55 PM - 8:55 PM • 2 stops
Knoxville → San Diego
10h 45m
6:45 AM - 4:30 PM • 1 stop
Southwest Airlines
Sep 01 - Sep 08, Economy
Knoxville → San Diego
10h 26m
6:00 AM - 9:26 AM • 1 stop
Knoxville → San Diego
43h 58m
11:04 AM - 4:42 PM • 2 stops
Delta Airlines
Sep 01 - Sep 08, Economy
Knoxville → San Diego
15h 41m
6:35 AM - 1:16 PM • 1 stop
Knoxville → San Diego
22h 39m
6:15 AM - 11:14 PM • 2 stops
Delta Airlines
Flying to San Diego soon? We've surfaced some of the most affordable last-minute flights from Knoxville to San Diego, ideal for urgent plans or spontaneous trips.
Sep 01 - Sep 08, Economy
Knoxville → San Diego
13h 20m
1:55 PM - 6:55 PM • 1 stop
Knoxville → San Diego
10h 45m
6:45 AM - 4:30 PM • 1 stop
Southwest Airlines
Sep 01 - Sep 08, Economy
Knoxville → San Diego
15h
7:00 AM - 1:00 PM • 2 stops
Knoxville → San Diego
10h 45m
6:45 AM - 4:30 PM • 1 stop
Southwest Airlines
Sep 01 - Sep 08, Economy
Knoxville → San Diego
16h 40m
1:55 PM - 8:55 PM • 2 stops
Knoxville → San Diego
10h 45m
6:45 AM - 4:30 PM • 1 stop
Southwest Airlines
Sep 01 - Sep 08, Economy
Knoxville → San Diego
10h 26m
6:00 AM - 9:26 AM • 1 stop
Knoxville → San Diego
43h 58m
11:04 AM - 4:42 PM • 2 stops
Delta Airlines
Sep 01 - Sep 08, Economy
Knoxville → San Diego
15h 41m
6:35 AM - 1:16 PM • 1 stop
Knoxville → San Diego
22h 39m
6:15 AM - 11:14 PM • 2 stops
Delta Airlines
FAQs on Knoxville to San Diego Flights
What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to SAN?
The most popular airline flying from Knoxville to San Diego are
Can I fly from TYS to SAN non-stop?
NO
Which airlines fly nonstop between Knoxville and San Diego?
The non-stop flights between Knoxville and San Diego are .
What’s the earliest departure time from TYS to SAN Airport?
The earliest flight leaves TYS at 6:00 am and lands in SAN - San Diego International
What are the airports in San Diego?
SAN
Can I make changes to my Knoxville to San Diego flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to SAN?
Read the fare rules of the Knoxville to San Diego air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and San Diego?
operate flights between Knoxville and San Diego
How long does a flight from Knoxville to San Diego take?
It takes approximately 4 hour to fly non-stop from TYS to SAN, which is 1902.22 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to San Diego (SAN) ?
In the past couple of days, the cheapest tickets to SAN from TYS were found on WN : USD 244
Do I need a passport to fly between TYS and SAN?
No
What’s the latest departure time from TYS to SAN ?
The last flight leaves TYS at 1:55 pm
Knoxville (TYS) to San Diego (SAN): Airport Information
| Origin Airport | McGhee Tyson , Knoxville, US |
| Destination Airport | San Diego International , San Diego, US |
| Distance | 1902 miles |
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