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Uncover the best deals on Knoxville to Fort Myers flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest TYS - RSW Flights
Useful information for finding best airline tickets from McGhee Tyson to Southwest Florida International on your next trip.
Cheapest Round Trip Flight
$211
Southwest Airlines
• 1 stop
• 14h 5m
Oct 14 – Oct 21
The cheapest round trip flight from Knoxville to Fort Myers (TYS-RSW-TYS) is currently $211
Fastest Flight
6h 42m
The fastest nonstop flight from Knoxville to Fort Myers (TYS-RSW) takes 6h 42m
Latest Flight Deals from Knoxville (TYS) to Fort Myers (RSW)
Compare and book low fare round-trip air tickets from Knoxville to Fort Myers. Ideal for travelers with confirmed return itineraries.
Oct 14 - Oct 21, Economy
Knoxville → Fort Myers
14h 5m
8:20 AM - 5:05 PM • 1 stop
Knoxville → Fort Myers
15h 20m
7:20 AM - 4:40 PM • 1 stop
Southwest Airlines
Oct 14 - Oct 21, Economy
Knoxville → Fort Myers
10h 5m
7:15 AM - 1:20 PM • 1 stop
Knoxville → Fort Myers
15h 20m
7:20 AM - 4:40 PM • 1 stop
Southwest Airlines
Oct 14 - Oct 21, Economy
Knoxville → Fort Myers
7h 28m
12:06 PM - 4:54 PM • 1 stop
Knoxville → Fort Myers
5h 55m
4:13 PM - 8:08 PM • 1 stop
Delta Airlines
Oct 14 - Oct 21, Economy
Knoxville → Fort Myers
7h 38m
7:09 AM - 12:07 PM • 1 stop
Knoxville → Fort Myers
5h 55m
4:13 PM - 8:08 PM • 1 stop
Delta Airlines
Oct 14 - Oct 21, Economy
Knoxville → Fort Myers
9h 18m
6:23 PM - 12:21 AM • 1 stop
Knoxville → Fort Myers
5h 55m
4:13 PM - 8:08 PM • 1 stop
Delta Airlines
Flying to Fort Myers soon? We've surfaced some of the most affordable last-minute flights from Knoxville to Fort Myers, ideal for urgent plans or spontaneous trips.
Oct 14 - Oct 21, Economy
Knoxville → Fort Myers
14h 5m
8:20 AM - 5:05 PM • 1 stop
Knoxville → Fort Myers
15h 20m
7:20 AM - 4:40 PM • 1 stop
Southwest Airlines
Oct 14 - Oct 21, Economy
Knoxville → Fort Myers
10h 5m
7:15 AM - 1:20 PM • 1 stop
Knoxville → Fort Myers
15h 20m
7:20 AM - 4:40 PM • 1 stop
Southwest Airlines
Oct 14 - Oct 21, Economy
Knoxville → Fort Myers
7h 28m
12:06 PM - 4:54 PM • 1 stop
Knoxville → Fort Myers
5h 55m
4:13 PM - 8:08 PM • 1 stop
Delta Airlines
Oct 14 - Oct 21, Economy
Knoxville → Fort Myers
7h 38m
7:09 AM - 12:07 PM • 1 stop
Knoxville → Fort Myers
5h 55m
4:13 PM - 8:08 PM • 1 stop
Delta Airlines
Oct 14 - Oct 21, Economy
Knoxville → Fort Myers
9h 18m
6:23 PM - 12:21 AM • 1 stop
Knoxville → Fort Myers
5h 55m
4:13 PM - 8:08 PM • 1 stop
Delta Airlines
FAQs on Knoxville to Fort Myers Flights
What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to RSW?
The most popular airline flying from Knoxville to Fort Myers are
Can I fly from TYS to RSW non-stop?
NO
Which airlines fly nonstop between Knoxville and Fort Myers?
The non-stop flights between Knoxville and Fort Myers are .
What’s the earliest departure time from TYS to RSW Airport?
The earliest flight leaves TYS at 6:56 am and lands in RSW - Southwest Florida International
What are the airports in Fort Myers?
RSW
Can I make changes to my Knoxville to Fort Myers flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to RSW?
Read the fare rules of the Knoxville to Fort Myers air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Fort Myers?
operate flights between Knoxville and Fort Myers
How long does a flight from Knoxville to Fort Myers take?
It takes approximately 2 hour to fly non-stop from TYS to RSW, which is 652.53 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Fort Myers (RSW) ?
In the past couple of days, the cheapest tickets to RSW from TYS were found on DL : USD 277
Do I need a passport to fly between TYS and RSW?
No
What’s the latest departure time from TYS to RSW ?
The last flight leaves TYS at 6:23 pm
Knoxville (TYS) to Fort Myers (RSW): Airport Information
| Origin Airport | McGhee Tyson , Knoxville, US |
| Destination Airport | Southwest Florida International , Fort Myers, US |
| Distance | 653 miles |
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