Lowest Prices
Uncover the best deals on Knoxville to Fort Myers flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest TYS - RSW Flights
Useful information for finding best airline tickets from McGhee Tyson to Southwest Florida International on your next trip.
Cheapest One way Flight
$342
Southwest Airlines
• 2 stops
• 37h 25m
Jul 19
The cheapest one way flight from Knoxville to Fort Myers (TYS-RSW) is currently $342
Fastest Flight
37h 25m
The fastest nonstop flight from Knoxville to Fort Myers (TYS-RSW) takes 37h 25m
Latest Flight Deals from Knoxville (TYS) to Fort Myers (RSW)
Explore competitive one-way airfare options for TYS - RSW flights. Best suited for flexible or open-ended travel plans.
Flying to Fort Myers soon? We've surfaced some of the most affordable last-minute flights from Knoxville to Fort Myers, ideal for urgent plans or spontaneous trips.
FAQs on Knoxville to Fort Myers Flights
What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to RSW?
The most popular airline flying from Knoxville to Fort Myers are
Can I fly from TYS to RSW non-stop?
NO
Which airlines fly nonstop between Knoxville and Fort Myers?
The non-stop flights between Knoxville and Fort Myers are .
What’s the earliest departure time from TYS to RSW Airport?
The earliest flight leaves TYS at 7:05 am and lands in RSW - Southwest Florida International
What are the airports in Fort Myers?
RSW
Can I make changes to my Knoxville to Fort Myers flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to RSW?
Read the fare rules of the Knoxville to Fort Myers air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Fort Myers?
operate flights between Knoxville and Fort Myers
How long does a flight from Knoxville to Fort Myers take?
It takes approximately 2 hour to fly non-stop from TYS to RSW, which is 652.53 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Fort Myers (RSW) ?
In the past couple of days, the cheapest tickets to RSW from TYS were found on WN : USD 388
Do I need a passport to fly between TYS and RSW?
No
What’s the latest departure time from TYS to RSW ?
The last flight leaves TYS at 7:00 pm
Knoxville (TYS) to Fort Myers (RSW): Airport Information
| Origin Airport | McGhee Tyson , Knoxville, US |
| Destination Airport | Southwest Florida International , Fort Myers, US |
| Distance | 653 miles |
More Flight Options for Knoxville (TYS) and Fort Myers (RSW)
Flights from Knoxville (TYS)
to Portland (PDX)
Flights from Knoxville (TYS)
to Las Vegas (LAS)
Flights from Knoxville (TYS)
to Detroit (DTW)
Flights from Knoxville (TYS)
to Los Angeles (LAX)
Flights from Knoxville (TYS)
to Houston (HOU)
Flights from Knoxville (TYS)
to Orlando (MCO)
Flights from Knoxville (TYS)
to Portland (PWM)
Flights from Knoxville (TYS)
to Harrisburg (MDT)
Flights from Knoxville (TYS)
to Cancún (CUN)
Flights from Knoxville (TYS)
to St Louis (STL)
Flights from Knoxville (TYS)
to Ontario (ONT)
Flights from Knoxville (TYS)
to Denver (DEN)
Flights from Knoxville (TYS)
to San Diego (SAN)
Flights from Knoxville (TYS)
to Grand Rapids (GRR)
Flights from Knoxville (TYS)
to Miami (MIA)
Flights from Knoxville (TYS)
to Houston (IAH)
Flights from Knoxville (TYS)
to Fort Lauderdale (FLL)
Flights from Knoxville (TYS)
to New York (LGA)
Flights from Knoxville (TYS)
to Newark (EWR)
Flights from Knoxville (TYS)
to New York (JFK)
Flights from Boston (BOS)
to Fort Myers (RSW)
Flights from Raleigh/Durham (RDU)
to Fort Myers (RSW)
Flights from Detroit (DTW)
to Fort Myers (RSW)
Flights from Philadelphia (PHL)
to Fort Myers (RSW)
Flights from Hartford (BDL)
to Fort Myers (RSW)
Flights from Phoenix (PHX)
to Fort Myers (RSW)
Flights from Newark (EWR)
to Fort Myers (RSW)
Flights from Newark (EWR)
to Fort Myers (RSW)
Flights from Cincinnati (CVG)
to Fort Myers (RSW)
Flights from Providence (PVD)
to Fort Myers (RSW)
Flights from Chicago (ORD)
to Fort Myers (RSW)
Flights from Toronto (YYZ)
to Fort Myers (RSW)
Flights from Appletonl (ATW)
to Fort Myers (RSW)
Flights from San Francisco (SFO)
to Fort Myers (RSW)
Flights from Portland (PWM)
to Fort Myers (RSW)
Flights from Minneapolis (MSP)
to Fort Myers (RSW)
Flights from Minneapolis (MSP)
to Fort Myers (RSW)
Flights from Pittsburgh (PIT)
to Fort Myers (RSW)
Flights from Denver (DEN)
to Fort Myers (RSW)
Flights from Indianapolis (IND)
to Fort Myers (RSW)
Cheap flights to North America (NA)
Cheap flights to United States (US)
Cheap flights to Florida (US-FL)
Cheap flights to Tennessee (US-TN)
Cheap flights from North America (NA)
Cheap flights from United States (US)
Cheap flights from Florida (US-FL)
Cheap flights from Tennessee (US-TN)
Flights to Fort Myers (RSW)
Flights to Knoxville (TYS)
Flights from Fort Myers (RSW)
Flights from Fort Myers (RSW)
to Knoxville (TYS)
Flights from Knoxville (TYS)
Why Fareleaders for TYS to RSW Plane Tickets
New Deals Everyday
Get the best prices on TYS to RSW flights—we update our fares daily so you never miss a saving.
No Service Fees
Compare hundreds of Knoxville to Fort Myers flights and secure the best deals—we never add any service fees.