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Good to Know: Cheapest and Fastest TYS - BUF Flights
Useful information for finding best airline tickets from McGhee Tyson to Buffalo Niagara International on your next trip.
Cheapest Round Trip Flight
$588
Southwest Airlines
• 1 stop
• 13h 20m
Aug 08 – Aug 15
The cheapest round trip flight from Knoxville to Buffalo (TYS-BUF-TYS) is currently $588
Fastest Flight
13h 20m
The fastest nonstop flight from Knoxville to Buffalo (TYS-BUF) takes 13h 20m
Top Airlines Flying from Knoxville to Buffalo
Latest Flight Deals from Knoxville (TYS) to Buffalo (BUF)
Compare and book low fare round-trip air tickets from Knoxville to Buffalo. Ideal for travelers with confirmed return itineraries.
Aug 08 - Aug 15, Economy
Knoxville → Buffalo
13h 20m
12:30 PM - 8:30 PM • 1 stop
Knoxville → Buffalo
13h 55m
6:05 AM - 2:40 PM • 1 stop
Southwest Airlines
Aug 08 - Aug 15, Economy
Knoxville → Buffalo
14h 15m
7:50 AM - 4:45 PM • 2 stops
Knoxville → Buffalo
5h 50m
3:30 PM - 7:20 PM • 1 stop
Southwest Airlines
Aug 08 - Aug 15, Economy
Knoxville → Buffalo
15h 55m
6:50 AM - 4:45 PM • 2 stops
Knoxville → Buffalo
13h 55m
6:05 AM - 2:40 PM • 1 stop
Southwest Airlines
Aug 08 - Aug 15, Economy
Knoxville → Buffalo
13h 55m
12:30 PM - 9:05 PM • 2 stops
Knoxville → Buffalo
12h 10m
10:10 AM - 5:40 PM • 1 stop
Southwest Airlines
Aug 08 - Aug 15, Economy
Knoxville → Buffalo
17h 30m
6:50 AM - 5:40 PM • 2 stops
Knoxville → Buffalo
14h 15m
5:45 AM - 2:40 PM • 2 stops
Southwest Airlines
Flying to Buffalo soon? We've surfaced some of the most affordable last-minute flights from Knoxville to Buffalo, ideal for urgent plans or spontaneous trips.
Aug 08 - Aug 15, Economy
Knoxville → Buffalo
13h 20m
12:30 PM - 8:30 PM • 1 stop
Knoxville → Buffalo
13h 55m
6:05 AM - 2:40 PM • 1 stop
Southwest Airlines
Aug 08 - Aug 15, Economy
Knoxville → Buffalo
14h 15m
7:50 AM - 4:45 PM • 2 stops
Knoxville → Buffalo
5h 50m
3:30 PM - 7:20 PM • 1 stop
Southwest Airlines
Aug 08 - Aug 15, Economy
Knoxville → Buffalo
15h 55m
6:50 AM - 4:45 PM • 2 stops
Knoxville → Buffalo
13h 55m
6:05 AM - 2:40 PM • 1 stop
Southwest Airlines
Aug 08 - Aug 15, Economy
Knoxville → Buffalo
13h 55m
12:30 PM - 9:05 PM • 2 stops
Knoxville → Buffalo
12h 10m
10:10 AM - 5:40 PM • 1 stop
Southwest Airlines
Aug 08 - Aug 15, Economy
Knoxville → Buffalo
17h 30m
6:50 AM - 5:40 PM • 2 stops
Knoxville → Buffalo
14h 15m
5:45 AM - 2:40 PM • 2 stops
Southwest Airlines
FAQs on Knoxville to Buffalo Flights
What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to BUF?
The most popular airline flying from Knoxville to Buffalo are
Can I fly from TYS to BUF non-stop?
NO
Which airlines fly nonstop between Knoxville and Buffalo?
The non-stop flights between Knoxville and Buffalo are .
What’s the earliest departure time from TYS to BUF Airport?
The earliest flight leaves TYS at 6:50 am and lands in BUF - Buffalo Niagara International
What are the airports in Buffalo?
BUF
Can I make changes to my Knoxville to Buffalo flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to BUF?
Read the fare rules of the Knoxville to Buffalo air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Buffalo?
operate flights between Knoxville and Buffalo
How long does a flight from Knoxville to Buffalo take?
It takes approximately 2 hour to fly non-stop from TYS to BUF, which is 566.52 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Buffalo (BUF) ?
In the past couple of days, the cheapest tickets to BUF from TYS were found on WN : USD 599
Do I need a passport to fly between TYS and BUF?
No
What’s the latest departure time from TYS to BUF ?
The last flight leaves TYS at 12:30 pm
Knoxville (TYS) to Buffalo (BUF): Airport Information
| Origin Airport | McGhee Tyson , Knoxville, US |
| Destination Airport | Buffalo Niagara International , Buffalo, US |
| Distance | 567 miles |
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