Cheap Flight Tickets from Islip (ISP) to Knoxville (TYS), Starting at $741

Good to Know: Cheapest and Fastest ISP - TYS Flights

Useful information for finding best airline tickets from Long Island Mac Arthur to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$741

WN Southwest Airlines • 1 stop • 15h 5m

Sep 27 – Oct 04

The cheapest round trip flight from Islip to Knoxville (ISP-TYS-ISP) is currently $741

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Fastest Flight

13h 20m

The fastest nonstop flight from Islip to Knoxville (ISP-TYS) takes 13h 20m

Top Airlines Flying from Islip to Knoxville

Southwest Airlines-WN

Southwest Airlines

Latest Flight Deals from Islip (ISP) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Islip to Knoxville. Ideal for travelers with confirmed return itineraries.

Sep 27 - Oct 04, Economy
WN
Islip → Knoxville
15h 5m
12:45 PM - 9:50 PM • 1 stop
WN
Islip → Knoxville
18h 30m
12:45 PM - 11:55 PM • 1 stop
$741
Southwest Airlines
Sep 27 - Oct 04, Economy
WN
Islip → Knoxville
17h 10m
10:20 AM - 8:50 PM • 2 stops
WN
Islip → Knoxville
18h 30m
12:45 PM - 11:55 PM • 1 stop
$747
Southwest Airlines
Sep 27 - Oct 04, Economy
WN
Islip → Knoxville
13h 20m
7:00 AM - 3:00 PM • 1 stop
WN
Islip → Knoxville
18h 30m
6:25 AM - 5:35 PM • 2 stops
$747
Southwest Airlines
Sep 27 - Oct 04, Economy
WN
Islip → Knoxville
19h 15m
7:00 AM - 6:55 PM • 2 stops
WN
Islip → Knoxville
18h 30m
12:45 PM - 11:55 PM • 1 stop
$747
Southwest Airlines
Sep 27 - Oct 04, Economy
WN
Islip → Knoxville
13h 20m
7:00 AM - 3:00 PM • 1 stop
WN
Islip → Knoxville
18h 30m
6:25 AM - 5:35 PM • 3 stops
$752
Southwest Airlines
Sep 27 - Oct 04, Economy
WN
Islip → Knoxville
14h
6:20 AM - 3:00 PM • 2 stops
WN
Islip → Knoxville
17h 35m
12:45 PM - 11:40 PM • 3 stops
$757
Southwest Airlines

Fly from Islip to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Islip to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Islip to Knoxville Flights

What are the airports in Islip?
ISP
What’s the most popular airline flying from ISP to TYS?
The most popular airline flying from Islip to Knoxville are
Can I fly from ISP to TYS non-stop?
NO
Which airlines fly nonstop between Islip and Knoxville?
The non-stop flights between Islip and Knoxville are .
What’s the earliest departure time from ISP to TYS Airport?
The earliest flight leaves ISP at 6:20 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Islip to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from ISP to TYS?
Read the fare rules of the Islip to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Islip and Knoxville?
operate flights between Islip and Knoxville
How long does a flight from Islip to Knoxville take?
It takes approximately 2 hour to fly non-stop from ISP to TYS, which is 683.9 miles by air.
Which airlines provide the cheapest flights from Islip (ISP) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from ISP were found on WN : USD 741
Do I need a passport to fly between ISP and TYS?
No
What’s the latest departure time from ISP to TYS ?
The last flight leaves ISP at 12:45 pm

Islip (ISP) to Knoxville (TYS): Airport Information

Origin Airport Long Island Mac Arthur , Islip, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 684 miles

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