Cheap Flight Tickets from Fort Myers (RSW) to Knoxville (TYS), Starting at $153

Good to Know: Cheapest and Fastest RSW - TYS Flights

Useful information for finding best airline tickets from Southwest Florida International to McGhee Tyson on your next trip.

Cheapest Round Trip Flight

$153

WN Southwest Airlines • 1 stop • 7h 35m

Oct 17 – Oct 22

The cheapest round trip flight from Fort Myers to Knoxville (RSW-TYS-RSW) is currently $153

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Fastest Flight

5h 46m

The fastest nonstop flight from Fort Myers to Knoxville (RSW-TYS) takes 5h 46m

Top Airlines Flying from Fort Myers to Knoxville

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Fort Myers (RSW) to Knoxville (TYS)

Compare and book low fare round-trip air tickets from Fort Myers to Knoxville. Ideal for travelers with confirmed return itineraries.

Oct 17 - Oct 22, Economy
WN
Fort Myers → Knoxville
7h 35m
7:05 AM - 12:00 PM • 1 stop
WN
Fort Myers → Knoxville
12h 30m
8:20 AM - 4:10 PM • 1 stop
$153
Southwest Airlines
Oct 17 - Oct 22, Economy
WN
Fort Myers → Knoxville
12h 15m
12:05 PM - 7:40 PM • 1 stop
WN
Fort Myers → Knoxville
12h 30m
8:20 AM - 4:10 PM • 1 stop
$153
Southwest Airlines
Oct 17 - Oct 22, Economy
DL
Fort Myers → Knoxville
5h 46m
11:40 AM - 3:26 PM • 1 stop
DL
Fort Myers → Knoxville
7h 17m
10:29 AM - 3:06 PM • 1 stop
$165
Delta Airlines
Oct 17 - Oct 22, Economy
DL
Fort Myers → Knoxville
8h 36m
2:52 PM - 8:08 PM • 1 stop
DL
Fort Myers → Knoxville
7h 17m
10:29 AM - 3:06 PM • 1 stop
$165
Delta Airlines
Oct 17 - Oct 22, Economy
AA
Fort Myers → Knoxville
7h 8m
8:00 AM - 12:28 PM • 1 stop
AA
Fort Myers → Knoxville
9h 13m
6:06 PM - 11:59 PM • 1 stop
$255
American Airlines
Oct 17 - Oct 22, Economy
UA
Fort Myers → Knoxville
37h 1m
12:16 PM - 10:37 AM • 1 stop
UA
Fort Myers → Knoxville
25h 45m
7:25 PM - 11:10 AM • 1 stop
$543
United Airlines

Fly from Fort Myers to Knoxville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Fort Myers to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Fort Myers to Knoxville Flights

What are the airports in Fort Myers?
RSW
What’s the most popular airline flying from RSW to TYS?
The most popular airline flying from Fort Myers to Knoxville are
Can I fly from RSW to TYS non-stop?
NO
Which airlines fly nonstop between Fort Myers and Knoxville?
The non-stop flights between Fort Myers and Knoxville are .
What’s the earliest departure time from RSW to TYS Airport?
The earliest flight leaves RSW at 7:05 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Fort Myers to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from RSW to TYS?
Read the fare rules of the Fort Myers to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Fort Myers and Knoxville?
operate flights between Fort Myers and Knoxville
How long does a flight from Fort Myers to Knoxville take?
It takes approximately 2 hour to fly non-stop from RSW to TYS, which is 652.53 miles by air.
Which airlines provide the cheapest flights from Fort Myers (RSW) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from RSW were found on UA : USD 543
Do I need a passport to fly between RSW and TYS?
No
What’s the latest departure time from RSW to TYS ?
The last flight leaves RSW at 2:52 pm

Fort Myers (RSW) to Knoxville (TYS): Airport Information

Origin Airport Southwest Florida International , Fort Myers, US
Destination Airport McGhee Tyson , Knoxville, US
Distance 653 miles

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