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Uncover the best deals on Fort Myers to Knoxville flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest RSW - TYS Flights
Useful information for finding best airline tickets from Southwest Florida International to McGhee Tyson on your next trip.
Cheapest Round Trip Flight
$261
Southwest Airlines
• 1 stop
• 17h
Jul 18 – Jul 25
The cheapest round trip flight from Fort Myers to Knoxville (RSW-TYS-RSW) is currently $261
Fastest Flight
13h 36m
The fastest nonstop flight from Fort Myers to Knoxville (RSW-TYS) takes 13h 36m
Top Airlines Flying from Fort Myers to Knoxville
Latest Flight Deals from Fort Myers (RSW) to Knoxville (TYS)
Compare and book low fare round-trip air tickets from Fort Myers to Knoxville. Ideal for travelers with confirmed return itineraries.
Jul 18 - Jul 25, Economy
Fort Myers → Knoxville
17h
6:20 AM - 4:40 PM • 1 stop
Fort Myers → Knoxville
26h 40m
7:00 AM - 11:00 PM • 3 stops
Southwest Airlines
Jul 18 - Jul 25, Economy
Fort Myers → Knoxville
22h 25m
7:40 AM - 9:25 PM • 2 stops
Fort Myers → Knoxville
6h 40m
7:00 AM - 11:00 AM • 1 stop
Southwest Airlines
Jul 18 - Jul 25, Economy
Fort Myers → Knoxville
25h 35m
8:30 PM - 12:05 PM • 2 stops
Fort Myers → Knoxville
17h 20m
8:00 AM - 6:40 PM • 2 stops
Southwest Airlines
Jul 18 - Jul 25, Economy
Fort Myers → Knoxville
27h 31m
6:22 PM - 11:13 AM • 1 stop
Fort Myers → Knoxville
6h 46m
11:03 AM - 3:09 PM • 1 stop
American Airlines
Jul 18 - Jul 25, Economy
Fort Myers → Knoxville
47h 1m
7:00 AM - 11:21 AM • 1 stop
Fort Myers → Knoxville
8h 28m
5:45 AM - 10:53 AM • 1 stop
United Airlines
Flying to Knoxville soon? We've surfaced some of the most affordable last-minute flights from Fort Myers to Knoxville, ideal for urgent plans or spontaneous trips.
Jul 18 - Jul 25, Economy
Fort Myers → Knoxville
17h
6:20 AM - 4:40 PM • 1 stop
Fort Myers → Knoxville
26h 40m
7:00 AM - 11:00 PM • 3 stops
Southwest Airlines
Jul 18 - Jul 25, Economy
Fort Myers → Knoxville
22h 25m
7:40 AM - 9:25 PM • 2 stops
Fort Myers → Knoxville
6h 40m
7:00 AM - 11:00 AM • 1 stop
Southwest Airlines
Jul 18 - Jul 25, Economy
Fort Myers → Knoxville
25h 35m
8:30 PM - 12:05 PM • 2 stops
Fort Myers → Knoxville
17h 20m
8:00 AM - 6:40 PM • 2 stops
Southwest Airlines
Jul 18 - Jul 25, Economy
Fort Myers → Knoxville
27h 31m
6:22 PM - 11:13 AM • 1 stop
Fort Myers → Knoxville
6h 46m
11:03 AM - 3:09 PM • 1 stop
American Airlines
Jul 18 - Jul 25, Economy
Fort Myers → Knoxville
47h 1m
7:00 AM - 11:21 AM • 1 stop
Fort Myers → Knoxville
8h 28m
5:45 AM - 10:53 AM • 1 stop
United Airlines
FAQs on Fort Myers to Knoxville Flights
What are the airports in Fort Myers?
RSW
What’s the most popular airline flying from RSW to TYS?
The most popular airline flying from Fort Myers to Knoxville are
Can I fly from RSW to TYS non-stop?
NO
Which airlines fly nonstop between Fort Myers and Knoxville?
The non-stop flights between Fort Myers and Knoxville are .
What’s the earliest departure time from RSW to TYS Airport?
The earliest flight leaves RSW at 6:20 am and lands in TYS - McGhee Tyson
What are the airports in Knoxville?
TYS
Can I make changes to my Fort Myers to Knoxville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from RSW to TYS?
Read the fare rules of the Fort Myers to Knoxville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Fort Myers and Knoxville?
operate flights between Fort Myers and Knoxville
How long does a flight from Fort Myers to Knoxville take?
It takes approximately 2 hour to fly non-stop from RSW to TYS, which is 652.53 miles by air.
Which airlines provide the cheapest flights from Fort Myers (RSW) to Knoxville (TYS) ?
In the past couple of days, the cheapest tickets to TYS from RSW were found on WN : USD 276
Do I need a passport to fly between RSW and TYS?
No
What’s the latest departure time from RSW to TYS ?
The last flight leaves RSW at 8:30 pm
Fort Myers (RSW) to Knoxville (TYS): Airport Information
| Origin Airport | Southwest Florida International , Fort Myers, US |
| Destination Airport | McGhee Tyson , Knoxville, US |
| Distance | 653 miles |
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