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Good to Know: Cheapest and Fastest TYS - SFO Flights
Useful information for finding best airline tickets from McGhee Tyson to San Francisco International on your next trip.
Cheapest Round Trip Flight
$254
Southwest Airlines
• 2 stops
• 17h 10m
Oct 12 – Oct 21
The cheapest round trip flight from Knoxville to San Francisco (TYS-SFO-TYS) is currently $254
Cheapest One way Flight
$379
Southwest Airlines
• 2 stops
• 54h 15m
Aug 04
The cheapest one way flight from Knoxville to San Francisco (TYS-SFO) is currently $379
Fastest Flight
11h 53m
The fastest nonstop flight from Knoxville to San Francisco (TYS-SFO) takes 11h 53m
Top Airlines Flying from Knoxville to San Francisco
Latest Flight Deals from Knoxville (TYS) to San Francisco (SFO)
Compare and book low fare round-trip air tickets from Knoxville to San Francisco. Ideal for travelers with confirmed return itineraries.
Oct 12 - Oct 21, Economy
Knoxville → San Francisco
17h 10m
12:50 PM - 8:20 PM • 2 stops
Knoxville → San Francisco
10h 25m
6:15 AM - 3:40 PM • 1 stop
Southwest Airlines
Oct 12 - Oct 21, Economy
Knoxville → San Francisco
33h 40m
7:15 AM - 12:35 AM • 2 stops
Knoxville → San Francisco
10h 25m
6:15 AM - 3:40 PM • 1 stop
Southwest Airlines
Oct 12 - Oct 21, Economy
Knoxville → San Francisco
24h 5m
8:20 AM - 8:05 PM • 2 stops
Knoxville → San Francisco
10h 25m
6:15 AM - 3:40 PM • 1 stop
Southwest Airlines
Oct 12 - Oct 21, Economy
Knoxville → San Francisco
20h 25m
12:50 PM - 10:15 PM • 2 stops
Knoxville → San Francisco
10h 25m
6:15 AM - 3:40 PM • 1 stop
Southwest Airlines
Oct 12 - Oct 21, Economy
Knoxville → San Francisco
24h 5m
12:50 PM - 12:35 AM • 2 stops
Knoxville → San Francisco
10h 25m
6:15 AM - 3:40 PM • 1 stop
Southwest Airlines
Explore competitive one-way airfare options for TYS - SFO flights. Best suited for flexible or open-ended travel plans.
Aug 04, Economy
Knoxville → San Francisco
54h 15m
7:00 AM - 12:55 PM • 2 stops
Southwest Airlines
Aug 04, Economy
Knoxville → San Francisco
28h 50m
5:30 PM - 8:00 AM • 2 stops
Southwest Airlines
Aug 04, Economy
Knoxville → San Francisco
18h 26m
5:00 AM - 1:06 PM • 2 stops
American Airlines
Flying to San Francisco soon? We've surfaced some of the most affordable last-minute flights from Knoxville to San Francisco, ideal for urgent plans or spontaneous trips.
Jul 29 - Aug 05, Economy
Knoxville → San Francisco
12h 31m
5:37 AM - 10:28 AM • 1 stop
Knoxville → San Francisco
15h 48m
10:58 AM - 11:46 PM • 1 stop
American Airlines
Jul 29 - Aug 05, Economy
Knoxville → San Francisco
14h 16m
7:19 PM - 1:15 AM • 1 stop
Knoxville → San Francisco
12h 19m
10:05 AM - 8:44 PM • 1 stop
United Airlines
Jul 29 - Aug 05, Economy
Knoxville → San Francisco
13h 54m
11:57 AM - 5:31 PM • 1 stop
Knoxville → San Francisco
10h 59m
11:35 AM - 9:34 PM • 1 stop
Delta Airlines
Jul 29 - Aug 05, Economy
Knoxville → San Francisco
16h 42m
1:35 PM - 8:37 PM • 1 stop
Knoxville → San Francisco
10h 36m
12:43 PM - 10:19 PM • 1 stop
United Airlines
Jul 29 - Aug 05, Economy
Knoxville → San Francisco
13h 45m
12:10 PM - 5:35 PM • 1 stop
Knoxville → San Francisco
11h 53m
11:30 PM - 9:43 AM • 1 stop
United Airlines
FAQs on Knoxville to San Francisco Flights
What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to SFO?
The most popular airline flying from Knoxville to San Francisco are
Can I fly from TYS to SFO non-stop?
NO
Which airlines fly nonstop between Knoxville and San Francisco?
The non-stop flights between Knoxville and San Francisco are .
What’s the earliest departure time from TYS to SFO Airport?
The earliest flight leaves TYS at 5:00 am and lands in SFO - San Francisco International
What are the airports in San Francisco?
SFO
Can I make changes to my Knoxville to San Francisco flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to SFO?
Read the fare rules of the Knoxville to San Francisco air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and San Francisco?
operate flights between Knoxville and San Francisco
How long does a flight from Knoxville to San Francisco take?
It takes approximately 5 hour to fly non-stop from TYS to SFO, which is 2119.52 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to San Francisco (SFO) ?
In the past couple of days, the cheapest tickets to SFO from TYS were found on WN : USD 489
Do I need a passport to fly between TYS and SFO?
No
What’s the latest departure time from TYS to SFO ?
The last flight leaves TYS at 8:11 pm
Knoxville (TYS) to San Francisco (SFO): Airport Information
| Origin Airport | McGhee Tyson , Knoxville, US |
| Destination Airport | San Francisco International , San Francisco, US |
| Distance | 2120 miles |
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