Cheap Flight Tickets from Knoxville (TYS) to Myrtle Beach (MYR), Starting at $377

Good to Know: Cheapest and Fastest TYS - MYR Flights

Useful information for finding best airline tickets from McGhee Tyson to Myrtle Beach International on your next trip.

Cheapest Round Trip Flight

$377

WN Southwest Airlines • 2 stops • 25h 45m

Feb 12 – Feb 19

The cheapest round trip flight from Knoxville to Myrtle Beach (TYS-MYR-TYS) is currently $377

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Fastest Flight

7h 11m

The fastest nonstop flight from Knoxville to Myrtle Beach (TYS-MYR) takes 7h 11m

Top Airlines Flying from Knoxville to Myrtle Beach

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Knoxville (TYS) to Myrtle Beach (MYR)

Compare and book low fare round-trip air tickets from Knoxville to Myrtle Beach. Ideal for travelers with confirmed return itineraries.

Feb 12 - Feb 19, Economy
WN
Knoxville → Myrtle Beach
25h 45m
6:45 AM - 10:30 PM • 2 stops
WN
Knoxville → Myrtle Beach
18h 45m
10:30 AM - 9:55 PM • 2 stops
$377
Southwest Airlines
Feb 12 - Feb 19, Economy
WN
Knoxville → Myrtle Beach
25h 45m
6:45 AM - 10:30 PM • 3 stops
WN
Knoxville → Myrtle Beach
13h 30m
1:45 PM - 9:55 PM • 1 stop
$377
Southwest Airlines
Feb 12 - Feb 19, Economy
WN
Knoxville → Myrtle Beach
22h 35m
7:40 PM - 9:35 AM • 2 stops
WN
Knoxville → Myrtle Beach
13h 30m
1:45 PM - 9:55 PM • 1 stop
$420
Southwest Airlines
Feb 12 - Feb 19, Economy
AA
Knoxville → Myrtle Beach
9h 19m
5:57 PM - 11:56 PM • 1 stop
AA
Knoxville → Myrtle Beach
5h 27m
5:11 AM - 8:38 AM • 1 stop
$516
American Airlines
Feb 12 - Feb 19, Economy
AA
Knoxville → Myrtle Beach
7h 18m
2:50 PM - 7:28 PM • 1 stop
AA
Knoxville → Myrtle Beach
5h 27m
5:11 AM - 8:38 AM • 1 stop
$602
American Airlines
Feb 12 - Feb 19, Economy
AA
Knoxville → Myrtle Beach
7h 11m
2:50 PM - 10:28 PM • 1 stop
AA
Knoxville → Myrtle Beach
5h 27m
5:11 AM - 8:38 AM • 1 stop
$963
American Airlines

Fly from Knoxville to Myrtle Beach with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Knoxville to Myrtle Beach? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Knoxville to Myrtle Beach Flights

What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to MYR?
The most popular airline flying from Knoxville to Myrtle Beach are
Can I fly from TYS to MYR non-stop?
NO
Which airlines fly nonstop between Knoxville and Myrtle Beach?
The non-stop flights between Knoxville and Myrtle Beach are .
What’s the earliest departure time from TYS to MYR Airport?
The earliest flight leaves TYS at 6:45 am and lands in MYR - Myrtle Beach International
What are the airports in Myrtle Beach?
MYR
Can I make changes to my Knoxville to Myrtle Beach flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to MYR?
Read the fare rules of the Knoxville to Myrtle Beach air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Myrtle Beach?
operate flights between Knoxville and Myrtle Beach
How long does a flight from Knoxville to Myrtle Beach take?
It takes approximately 1 hour to fly non-stop from TYS to MYR, which is 323.45 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Myrtle Beach (MYR) ?
In the past couple of days, the cheapest tickets to MYR from TYS were found on WN : USD 377
Do I need a passport to fly between TYS and MYR?
No
What’s the latest departure time from TYS to MYR ?
The last flight leaves TYS at 7:40 pm

Knoxville (TYS) to Myrtle Beach (MYR): Airport Information

Origin Airport McGhee Tyson , Knoxville, US
Destination Airport Myrtle Beach International , Myrtle Beach, US
Distance 323 miles

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