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Uncover the best deals on Knoxville to Sioux Falls flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest TYS - FSD Flights
Useful information for finding best airline tickets from McGhee Tyson to Joe Foss Field on your next trip.
Cheapest Round Trip Flight
$281
Delta Airlines
• 1 stop
• 42h 16m
Nov 12 – Nov 15
The cheapest round trip flight from Knoxville to Sioux Falls (TYS-FSD-TYS) is currently $281
Fastest Flight
7h 26m
The fastest nonstop flight from Knoxville to Sioux Falls (TYS-FSD) takes 7h 26m
Top Airlines Flying from Knoxville to Sioux Falls
Latest Flight Deals from Knoxville (TYS) to Sioux Falls (FSD)
Compare and book low fare round-trip air tickets from Knoxville to Sioux Falls. Ideal for travelers with confirmed return itineraries.
Nov 12 - Nov 15, Economy
Knoxville → Sioux Falls
42h 16m
6:30 PM - 7:06 PM • 1 stop
Knoxville → Sioux Falls
7h
11:00 AM - 4:20 PM • 1 stop
Delta Airlines
Nov 12 - Nov 15, Economy
Knoxville → Sioux Falls
15h 46m
3:43 PM - 12:29 AM • 2 stops
Knoxville → Sioux Falls
8h 52m
12:14 PM - 6:46 PM • 1 stop
American Airlines
Nov 12 - Nov 15, Economy
Knoxville → Sioux Falls
15h 38m
8:49 AM - 5:27 PM • 2 stops
Knoxville → Sioux Falls
8h 52m
12:14 PM - 6:46 PM • 1 stop
American Airlines
Nov 12 - Nov 15, Economy
Knoxville → Sioux Falls
15h 3m
6:50 AM - 2:53 PM • 2 stops
Knoxville → Sioux Falls
8h 52m
12:14 PM - 6:46 PM • 1 stop
American Airlines
Nov 12 - Nov 15, Economy
Knoxville → Sioux Falls
7h 26m
7:52 AM - 11:38 AM • 1 stop
Knoxville → Sioux Falls
15h 37m
7:00 AM - 5:37 PM • 2 stops
American Airlines
FAQs on Knoxville to Sioux Falls Flights
What are the airports in Knoxville?
TYS
What’s the most popular airline flying from TYS to FSD?
The most popular airline flying from Knoxville to Sioux Falls are
Can I fly from TYS to FSD non-stop?
NO
Which airlines fly nonstop between Knoxville and Sioux Falls?
The non-stop flights between Knoxville and Sioux Falls are .
What’s the earliest departure time from TYS to FSD Airport?
The earliest flight leaves TYS at 6:50 am and lands in FSD - Joe Foss Field
What are the airports in Sioux Falls?
FSD
Can I make changes to my Knoxville to Sioux Falls flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from TYS to FSD?
Read the fare rules of the Knoxville to Sioux Falls air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Knoxville and Sioux Falls?
operate flights between Knoxville and Sioux Falls
How long does a flight from Knoxville to Sioux Falls take?
It takes approximately 2 hour to fly non-stop from TYS to FSD, which is 863.75 miles by air.
Which airlines provide the cheapest flights from Knoxville (TYS) to Sioux Falls (FSD) ?
In the past couple of days, the cheapest tickets to FSD from TYS were found on AA : USD 321
Do I need a passport to fly between TYS and FSD?
No
What’s the latest departure time from TYS to FSD ?
The last flight leaves TYS at 6:30 pm
Hotels in Sioux Falls (FSD)
5 hotels near Joe Foss Field — compare rates from top booking sites.
4-star hotel
Econo Lodge Le Mars
📍 1201 Hawkeye Ave Sw, Le Mars, Iowa 51031
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4-star hotel
Bridges Bay Resort
📍 630 Linden Drive, Arnolds Park, Iowa 51331
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4-star hotel
Sheraton Sioux Falls & Convention Center
📍 1211 N West Ave, Sioux Falls, South Dakota 57104
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3-star hotel
Hampton Inn Suites Brookings
📍 3017 Lefevre Drive, Brookings, Oregon 57006
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3-star hotel
Best Western U-bar Motel
📍 130 W Ash Street, Canistota, South Dakota 57012
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Hotel Deals in Sioux Falls (SD)
Settle Inn
7.1/10
★☆☆☆☆
✓ Free WiFi
$49/night
View Deal
Wyndham Hotels & Resorts
Super 8 By Wyndham Sioux Falls/41St Street
8.0/10
★★☆☆☆
Hotel
91.0 rooms
✓ Free WiFi
✓ Breakfast
📍 4100 W. 41St St., Sioux Falls (SD), South Dakota
Great care is taken to ensure guests experience comfort through top-notch services and amenities.Remain linked during your visit by utilizing the complimentary internet access available.The hotel off…
Check-in 03:00 PM · Check-out 11:00 AM
$62/night
View Deal
Wyndham Hotels & Resorts
Ramada by Wyndham Sioux Falls
6.4/10
★★☆☆☆
Hotel
66.0 rooms
✓ Free WiFi
✓ Breakfast
📍 407 South Lyons Avenue, Sioux Falls (SD), South Dakota
Experience an abundance of unparalleled facilities and features at Ramada by Wyndham Sioux Falls. Maintain seamless communication using the complimentary Wi-Fi at hotel.For visitors traveling by auto…
Check-in 03:00 PM · Check-out 11:00 AM
$62/night
View Deal
Wyndham Hotels & Resorts
Ramada by Wyndham Sioux Falls Airport - Waterpark & Event Center
7.8/10
★★★☆☆
Hotel
150.0 rooms
✓ Free WiFi
📍 1301 W Russell St, Sioux Falls (SD), South Dakota
Ramada by Wyndham Sioux Falls Airport - Waterpark & Event Center offers top-notch services and amenities, ensuring guests experience utmost comfort.Share your photos and respond to emails at your con…
Check-in 04:00 PM · Check-out 12:00 PM
$62/night
View Deal
Wyndham Hotels & Resorts
Microtel Inn & Suites by Wyndham Sioux Falls
7.5/10
★★☆☆☆
Hotel
68.0 rooms
✓ Free WiFi
✓ Breakfast
📍 2901 South Carolyn Avenue, Sioux Falls (SD)
Microtel Inn & Suites by Wyndham Sioux Falls offers top-notch services and amenities, ensuring guests experience utmost comfort.Share your photos and respond to emails at your convenience, thanks to …
Check-in 02:00 PM · Check-out 11:00 AM
$64/night
View Deal
Wyndham Hotels & Resorts
Baymont by Wyndham Sioux Falls North/I-29/Russell St
7.5/10
★★★☆☆
Hotel
43.0 rooms
✓ Free WiFi
✓ Breakfast
📍 3101 W Russell St., Sioux Falls (SD), South Dakota
At Baymont by Wyndham Sioux Falls North/I-29/Russell St, exceptional service and top-notch amenities create a memorable experience for guests. Complimentary internet access is available in the hotel …
Check-in 03:00 PM · Check-out 11:00 AM
$65/night
View Deal
Wyndham Hotels & Resorts
Days Inn by Wyndham Sioux Falls
7.7/10
★★☆☆☆
Hotel
79.0 rooms
✓ Free WiFi
✓ Breakfast
📍 3401 Gateway Blvd., Sioux Falls (SD), South Dakota
At Days Inn by Wyndham Sioux Falls, exceptional service and top-notch amenities create a memorable experience for guests. Complimentary internet access is available in the hotel to ensure you stay co…
Check-in 03:00 PM · Check-out 11:00 AM
$65/night
View Deal
Wyndham Hotels & Resorts
Days Inn by Wyndham Sioux Falls Airport
7.7/10
★★☆☆☆
Hotel
87.0 rooms
✓ Free WiFi
✓ Breakfast
📍 5001 N. Cliff Avenue, Sioux Falls (SD), South Dakota
Days Inn by Wyndham Sioux Falls Airport offers top-notch services and amenities, ensuring guests experience utmost comfort.Maintain seamless communication using the complimentary Wi-Fi at hotel.Effor…
Check-in 03:00 PM · Check-out 12:00 PM
$69/night
View Deal
Wyndham Hotels & Resorts
Super 8 By Wyndham Sioux Falls
7.7/10
★★☆☆☆
Hotel
56.0 rooms
✓ Free WiFi
✓ Breakfast
📍 2616 East 10Th Street, Sioux Falls (SD), South Dakota
Experience an abundance of unparalleled facilities and features at Super 8 By Wyndham Sioux Falls.Maintain seamless communication using the complimentary Wi-Fi at hotel.For visitors traveling by auto…
Check-in 03:00 PM · Check-out 11:00 AM
$69/night
View Deal
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Knoxville (TYS) to Sioux Falls (FSD): Airport Information
| Origin Airport | McGhee Tyson , Knoxville, US |
| Destination Airport | Joe Foss Field , Sioux Falls, US |
| Distance | 864 miles |
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