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Uncover the best deals on St Louis to Buffalo flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest STL - BUF Flights
Useful information for finding best airline tickets from Lambert St Louis International to Buffalo Niagara International on your next trip.
Cheapest Round Trip Flight
$634
Southwest Airlines
• 1 stop
• 10h 45m
Sep 02 – Sep 03
The cheapest round trip flight from St Louis to Buffalo (STL-BUF-STL) is currently $634
Cheapest One way Flight
$117
United Airlines
• 2 stops
• 15h 45m
Aug 24
The cheapest one way flight from St Louis to Buffalo (STL-BUF) is currently $117
Fastest Flight
5h 30m
The fastest nonstop flight from St Louis to Buffalo (STL-BUF) takes 5h 30m
Top Airlines Flying from St Louis to Buffalo
Latest Flight Deals from St Louis (STL) to Buffalo (BUF)
Compare and book low fare round-trip air tickets from St Louis to Buffalo. Ideal for travelers with confirmed return itineraries.
Sep 02 - Sep 03, Economy
St Louis → Buffalo
10h 45m
12:50 PM - 8:35 PM • 1 stop
St Louis → Buffalo
10h 30m
6:30 AM - 12:00 PM • 1 stop
Southwest Airlines
Sep 02 - Sep 03, Economy
St Louis → Buffalo
5h 30m
10:45 AM - 3:15 PM • 1 stop
St Louis → Buffalo
13h 40m
11:45 AM - 7:05 PM • 1 stop
Southwest Airlines
Sep 02 - Sep 03, Economy
St Louis → Buffalo
10h 55m
1:50 PM - 9:45 PM • 1 stop
St Louis → Buffalo
6h 40m
7:10 PM - 10:10 PM • 1 stop
Southwest Airlines
Sep 02 - Sep 03, Economy
St Louis → Buffalo
12h 5m
5:55 AM - 2:20 PM • 1 stop
St Louis → Buffalo
6h 40m
7:10 PM - 10:10 PM • 1 stop
Southwest Airlines
Sep 02 - Sep 03, Economy
St Louis → Buffalo
15h 10m
8:35 AM - 6:45 PM • 1 stop
St Louis → Buffalo
6h 40m
7:10 PM - 10:10 PM • 1 stop
Southwest Airlines
Explore competitive one-way airfare options for STL - BUF flights. Best suited for flexible or open-ended travel plans.
Flying to Buffalo soon? We've surfaced some of the most affordable last-minute flights from St Louis to Buffalo, ideal for urgent plans or spontaneous trips.
FAQs on St Louis to Buffalo Flights
What are the airports in St Louis?
STL
What’s the most popular airline flying from STL to BUF?
The most popular airline flying from St Louis to Buffalo are
Can I fly from STL to BUF non-stop?
NO
Which airlines fly nonstop between St Louis and Buffalo?
The non-stop flights between St Louis and Buffalo are .
What’s the earliest departure time from STL to BUF Airport?
The earliest flight leaves STL at 5:55 am and lands in BUF - Buffalo Niagara International
What are the airports in Buffalo?
BUF
Can I make changes to my St Louis to Buffalo flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from STL to BUF?
Read the fare rules of the St Louis to Buffalo air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from St Louis and Buffalo?
operate flights between St Louis and Buffalo
How long does a flight from St Louis to Buffalo take?
It takes approximately 2 hour to fly non-stop from STL to BUF, which is 674.16 miles by air.
Which airlines provide the cheapest flights from St Louis (STL) to Buffalo (BUF) ?
In the past couple of days, the cheapest tickets to BUF from STL were found on AA : USD 406
Do I need a passport to fly between STL and BUF?
No
What’s the latest departure time from STL to BUF ?
The last flight leaves STL at 8:07 pm
St Louis (STL) to Buffalo (BUF): Airport Information
| Origin Airport | Lambert St Louis International , St Louis, US |
| Destination Airport | Buffalo Niagara International , Buffalo, US |
| Distance | 674 miles |
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