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Uncover the best deals on Mexico City to Santiago flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest MEX - SCL Flights
Useful information for finding best airline tickets from Licenciado Benito Juarez International to Comodoro Arturo Merino Benítez on your next trip.
Cheapest Round Trip Flight
$961
Avianca
• 1 stop
• 18h 55m
Sep 19 – Sep 22
The cheapest round trip flight from Mexico City to Santiago (MEX-SCL-MEX) is currently $961
Cheapest Direct Flight
$1082
LATAM Airlines
• nonstop
• 18h 55m
Sep 19
The cheapest nonstop flight from Mexico City to Santiago (MEX-SCL) is currently $1082
Fastest Flight
14h 10m
The fastest nonstop flight from Mexico City to Santiago (MEX-SCL) takes 14h 10m
Top Airlines Flying from Mexico City to Santiago
Latest Flight Deals from Mexico City (MEX) to Santiago (SCL)
Compare and book low fare round-trip air tickets from Mexico City to Santiago. Ideal for travelers with confirmed return itineraries.
Sep 19 - Sep 22, Economy
Mexico City → Santiago
18h 55m
12:40 AM - 3:15 PM • 1 stop
Mexico City → Santiago
22h 5m
7:40 AM - 6:05 PM • 1 stop
Avianca
Sep 19 - Sep 22, Economy
Mexico City → Santiago
18h 55m
8:05 PM - 7:55 AM • nonstop
Mexico City → Santiago
22h 5m
4:20 PM - 1:50 PM • 2 stops
LATAM Airlines
Sep 19 - Sep 22, Economy
Mexico City → Santiago
37h 35m
5:20 PM - 7:15 PM • 1 stop
Mexico City → Santiago
40h 30m
4:20 PM - 1:50 PM • 2 stops
LATAM Airlines
Sep 19 - Sep 22, Economy
Mexico City → Santiago
18h 55m
11:01 AM - 5:03 AM • 2 stops
Mexico City → Santiago
22h 5m
9:30 AM - 3:45 PM • nonstop
Volaris Airline
Sep 19 - Sep 22, Economy
Mexico City → Santiago
19h 6m
1:10 PM - 3:56 AM • 1 stop
Mexico City → Santiago
22h 5m
7:40 AM - 6:05 PM • 1 stop
Copa Airlines
Flying to Santiago soon? We've surfaced some of the most affordable last-minute flights from Mexico City to Santiago, ideal for urgent plans or spontaneous trips.
Sep 19 - Sep 22, Economy
Mexico City → Santiago
18h 55m
12:40 AM - 3:15 PM • 1 stop
Mexico City → Santiago
22h 5m
7:40 AM - 6:05 PM • 1 stop
Avianca
Sep 19 - Sep 22, Economy
Mexico City → Santiago
18h 55m
8:05 PM - 7:55 AM • nonstop
Mexico City → Santiago
22h 5m
4:20 PM - 1:50 PM • 2 stops
LATAM Airlines
Sep 19 - Sep 22, Economy
Mexico City → Santiago
37h 35m
5:20 PM - 7:15 PM • 1 stop
Mexico City → Santiago
40h 30m
4:20 PM - 1:50 PM • 2 stops
LATAM Airlines
Sep 19 - Sep 22, Economy
Mexico City → Santiago
18h 55m
11:01 AM - 5:03 AM • 2 stops
Mexico City → Santiago
22h 5m
9:30 AM - 3:45 PM • nonstop
Volaris Airline
Sep 19 - Sep 22, Economy
Mexico City → Santiago
19h 6m
1:10 PM - 3:56 AM • 1 stop
Mexico City → Santiago
22h 5m
7:40 AM - 6:05 PM • 1 stop
Copa Airlines
Looking for the fastest way to Santiago? These direct flight options from MEX to SCL offer both convenience and value—no layovers, just straight to your destination.
Sep 19 - Sep 22, Economy
Mexico City → Santiago
18h 55m
8:05 PM - 7:55 AM • nonstop
Mexico City → Santiago
22h 5m
9:30 AM - 3:45 PM • nonstop
LATAM Airlines
Sep 16 - Sep 22, Economy
Mexico City → Santiago
14h 10m
8:05 PM - 7:55 AM • nonstop
Mexico City → Santiago
15h 15m
9:30 AM - 3:45 PM • nonstop
LATAM Airlines
Sep 10 - Oct 01, Economy
Mexico City → Santiago
14h 10m
8:05 PM - 7:55 AM • nonstop
Mexico City → Santiago
15h 15m
9:30 AM - 3:45 PM • nonstop
LATAM Airlines
Sep 09 - Sep 30, Economy
Mexico City → Santiago
14h 10m
8:05 PM - 7:55 AM • nonstop
Mexico City → Santiago
15h 15m
9:30 AM - 3:45 PM • nonstop
LATAM Airlines
FAQs on Mexico City to Santiago Flights
What are the airports in Mexico City?
MEX
What’s the most popular airline flying from MEX to SCL?
The most popular airline flying from Mexico City to Santiago are
Can I fly from MEX to SCL non-stop?
Yes, you can fly MEX to SCL non-stop on
Which airlines fly nonstop between Mexico City and Santiago?
The non-stop flights between Mexico City and Santiago are .
What’s the earliest departure time from MEX to SCL Airport?
The earliest flight leaves MEX at 12:40 am and lands in SCL - Comodoro Arturo Merino Benítez
What are the airports in Santiago?
SCL
Can I make changes to my Mexico City to Santiago flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from MEX to SCL?
Read the fare rules of the Mexico City to Santiago air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Mexico City and Santiago?
operate flights between Mexico City and Santiago
How long does a flight from Mexico City to Santiago take?
It takes approximately 8 hour to fly non-stop from MEX to SCL, which is 4084.58 miles by air.
Which airlines provide the cheapest flights from Mexico City (MEX) to Santiago (SCL) ?
In the past couple of days, the cheapest tickets to SCL from MEX were found on Y4 : USD 1531
Do I need a passport to fly between MEX and SCL?
Yes
What’s the latest departure time from MEX to SCL ?
The last flight leaves MEX at 8:0500 pm
Mexico City (MEX) to Santiago (SCL): Airport Information
| Origin Airport | Licenciado Benito Juarez International , Mexico City, MX |
| Destination Airport | Comodoro Arturo Merino Benítez, Santiago, CL |
| Distance | 4085 miles |
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