Lowest Prices
Uncover the best deals on Guayaquil to Santiago flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest GYE - SCL Flights
Useful information for finding best airline tickets from José Joaquín de Olmedo International to Comodoro Arturo Merino Benítez on your next trip.
Cheapest Round Trip Flight
$584
Avianca
• 1 stop
• 45h 54m
Sep 23 – Sep 28
The cheapest round trip flight from Guayaquil to Santiago (GYE-SCL-GYE) is currently $584
Cheapest Direct Flight
$633
LATAM Airlines
• nonstop
• 7h 31m
Sep 24
The cheapest nonstop flight from Guayaquil to Santiago (GYE-SCL) is currently $633
Fastest Flight
7h 31m
The fastest nonstop flight from Guayaquil to Santiago (GYE-SCL) takes 7h 31m
Top Airlines Flying from Guayaquil to Santiago
Latest Flight Deals from Guayaquil (GYE) to Santiago (SCL)
Compare and book low fare round-trip air tickets from Guayaquil to Santiago. Ideal for travelers with confirmed return itineraries.
Sep 23 - Sep 28, Economy
Guayaquil → Santiago
45h 54m
3:45 PM - 5:45 AM • 1 stop
Guayaquil → Santiago
53h 27m
1:30 AM - 2:50 PM • 2 stops
Avianca
Sep 23 - Sep 28, Economy
Guayaquil → Santiago
12h 20m
8:45 PM - 6:25 AM • 1 stop
Guayaquil → Santiago
8h 38m
1:45 AM - 5:03 AM • nonstop
LATAM Airlines
Sep 23 - Sep 28, Economy
Guayaquil → Santiago
20h
8:45 PM - 10:45 AM • 2 stops
Guayaquil → Santiago
13h 20m
7:45 PM - 1:45 AM • 1 stop
LATAM Airlines
Sep 23 - Sep 28, Economy
Guayaquil → Santiago
18h 26m
8:45 PM - 9:51 AM • 2 stops
Guayaquil → Santiago
15h 55m
5:50 PM - 1:45 AM • 1 stop
LATAM Airlines
Sep 23 - Sep 28, Economy
Guayaquil → Santiago
28h 30m
8:45 PM - 3:55 PM • 2 stops
Guayaquil → Santiago
13h 20m
7:45 PM - 1:45 AM • 1 stop
LATAM Airlines
Flying to Santiago soon? We've surfaced some of the most affordable last-minute flights from Guayaquil to Santiago, ideal for urgent plans or spontaneous trips.
Looking for the fastest way to Santiago? These direct flight options from GYE to SCL offer both convenience and value—no layovers, just straight to your destination.
Sep 24 - Sep 26, Economy
Guayaquil → Santiago
7h 31m
5:38 PM - 12:29 AM • nonstop
Guayaquil → Santiago
8h 38m
1:45 AM - 5:03 AM • nonstop
LATAM Airlines
Sep 23 - Sep 28, Economy
Guayaquil → Santiago
7h 31m
5:38 PM - 12:29 AM • nonstop
Guayaquil → Santiago
8h 38m
1:45 AM - 5:03 AM • nonstop
LATAM Airlines
FAQs on Guayaquil to Santiago Flights
What are the airports in Guayaquil?
GYE
What’s the most popular airline flying from GYE to SCL?
The most popular airline flying from Guayaquil to Santiago are
Can I fly from GYE to SCL non-stop?
Yes, you can fly GYE to SCL non-stop on
Which airlines fly nonstop between Guayaquil and Santiago?
The non-stop flights between Guayaquil and Santiago are .
What’s the earliest departure time from GYE to SCL Airport?
The earliest flight leaves GYE at 3:45 pm and lands in SCL - Comodoro Arturo Merino Benítez
What are the airports in Santiago?
SCL
Can I make changes to my Guayaquil to Santiago flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from GYE to SCL?
Read the fare rules of the Guayaquil to Santiago air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Guayaquil and Santiago?
operate flights between Guayaquil and Santiago
How long does a flight from Guayaquil to Santiago take?
It takes approximately 5 hour to fly non-stop from GYE to SCL, which is 2227.97 miles by air.
Which airlines provide the cheapest flights from Guayaquil (GYE) to Santiago (SCL) ?
In the past couple of days, the cheapest tickets to SCL from GYE were found on LA : USD 708
Do I need a passport to fly between GYE and SCL?
Yes
What’s the latest departure time from GYE to SCL ?
The last flight leaves GYE at 8:45 pm
Guayaquil (GYE) to Santiago (SCL): Airport Information
| Origin Airport | José Joaquín de Olmedo International , Guayaquil, EC |
| Destination Airport | Comodoro Arturo Merino Benítez, Santiago, CL |
| Distance | 2228 miles |
More Flight Options for Guayaquil (GYE) and Santiago (SCL)
Flights from Guayaquil (GYE)
to Madrid (MAD)
Flights from Guayaquil (GYE)
to New York (JFK)
Flights from Guayaquil (GYE)
to Newark (EWR)
Flights from Guayaquil (GYE)
to Newark (EWR)
Flights from Guayaquil (GYE)
to Buenos Aires (EZE)
Flights from Guayaquil (GYE)
to New York (NYC)
Flights from Guayaquil (GYE)
to Miami (MIA)
Flights from Guayaquil (GYE)
to Bogota (BOG)
Flights from Guayaquil (GYE)
to Santiago (SCL)
Flights from Guayaquil (GYE)
to Fort Lauderdale (FLL)
Flights from Guayaquil (GYE)
to Los Angeles (LAX)
Flights from Guayaquil (GYE)
to Orlando (MCO)
Flights from Guayaquil (GYE)
to Tocumen (PTY)
Flights from Guayaquil (GYE)
to Tocumen (PTY)
Flights from Guayaquil (GYE)
to San Andrés (ADZ)
Flights from Guayaquil (GYE)
to Barcelona (BCN)
Flights from Guayaquil (GYE)
to New York (LGA)
Flights from Guayaquil (GYE)
to Ontario (ONT)
Flights from Guayaquil (GYE)
to Santiago (SCL)
Flights from Guatemala City (GUA)
to Santiago (SCL)
Flights from Bogota (BOG)
to Santiago (SCL)
Flights from London (LHR)
to Santiago (SCL)
Flights from Miami (MIA)
to Santiago (SCL)
Flights from Buenos Aires (EZE)
to Santiago (SCL)
Flights from Lima (LIM)
to Santiago (SCL)
Flights from New York (JFK)
to Santiago (SCL)
Cheap flights to South America (SA)
Cheap flights to Chile (CL)
Cheap flights to Ecuador (EC)
Cheap flights from South America (SA)
Cheap flights from Chile (CL)
Cheap flights from Ecuador (EC)
Flights to Guayaquil (GYE)
Flights to Santiago (SCL)
Flights from Guayaquil (GYE)
Flights from Santiago (SCL)
Why Fareleaders for GYE to SCL Plane Tickets
New Deals Everyday
Get the best prices on GYE to SCL flights—we update our fares daily so you never miss a saving.
No Service Fees
Compare hundreds of Guayaquil to Santiago flights and secure the best deals—we never add any service fees.