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Uncover the best deals on Jacksonville to St Louis flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest JAX - STL Flights
Useful information for finding best airline tickets from Jacksonville International to Lambert St Louis International on your next trip.
Cheapest Round Trip Flight
$577
Southwest Airlines
• 1 stop
• 8h 40m
Jun 26 – Jul 03
The cheapest round trip flight from Jacksonville to St Louis (JAX-STL-JAX) is currently $577
Cheapest Direct Flight
$320
Southwest Airlines
• nonstop
• 3h 30m
Jun 27
The cheapest nonstop flight from Jacksonville to St Louis (JAX-STL) is currently $320
Fastest Flight
3h 30m
The fastest nonstop flight from Jacksonville to St Louis (JAX-STL) takes 3h 30m
Top Airlines Flying from Jacksonville to St Louis
Latest Flight Deals from Jacksonville (JAX) to St Louis (STL)
Compare and book low fare round-trip air tickets from Jacksonville to St Louis. Ideal for travelers with confirmed return itineraries.
Jun 26 - Jul 03, Economy
Jacksonville → St Louis
8h 40m
2:50 PM - 7:10 PM • 1 stop
Jacksonville → St Louis
3h 20m
3:35 PM - 6:35 PM • nonstop
Southwest Airlines
Jun 26 - Jul 03, Economy
Jacksonville → St Louis
15h 55m
2:15 PM - 11:10 PM • 1 stop
Jacksonville → St Louis
3h 20m
3:35 PM - 6:35 PM • nonstop
Southwest Airlines
Jun 26 - Jul 03, Economy
Jacksonville → St Louis
17h 30m
11:00 AM - 8:50 PM • 2 stops
Jacksonville → St Louis
22h 30m
10:15 PM - 1:05 PM • 2 stops
Southwest Airlines
Jun 26 - Jul 03, Economy
Jacksonville → St Louis
13h 50m
11:00 AM - 6:30 PM • 2 stops
Jacksonville → St Louis
22h 30m
10:15 PM - 1:05 PM • 2 stops
Southwest Airlines
Jun 27 - Jul 04, Economy
Jacksonville → St Louis
40h 50m
6:28 PM - 6:18 PM • 2 stops
Jacksonville → St Louis
23h 52m
5:06 PM - 8:38 AM • 2 stops
Frontier Airlines
Flying to St Louis soon? We've surfaced some of the most affordable last-minute flights from Jacksonville to St Louis, ideal for urgent plans or spontaneous trips.
Jun 26 - Jul 03, Economy
Jacksonville → St Louis
8h 40m
2:50 PM - 7:10 PM • 1 stop
Jacksonville → St Louis
3h 20m
3:35 PM - 6:35 PM • nonstop
Southwest Airlines
Jun 26 - Jul 03, Economy
Jacksonville → St Louis
15h 55m
2:15 PM - 11:10 PM • 1 stop
Jacksonville → St Louis
3h 20m
3:35 PM - 6:35 PM • nonstop
Southwest Airlines
Jun 26 - Jul 03, Economy
Jacksonville → St Louis
17h 30m
11:00 AM - 8:50 PM • 2 stops
Jacksonville → St Louis
22h 30m
10:15 PM - 1:05 PM • 2 stops
Southwest Airlines
Jun 26 - Jul 03, Economy
Jacksonville → St Louis
13h 50m
11:00 AM - 6:30 PM • 2 stops
Jacksonville → St Louis
22h 30m
10:15 PM - 1:05 PM • 2 stops
Southwest Airlines
Jun 27 - Jul 04, Economy
Jacksonville → St Louis
40h 50m
6:28 PM - 6:18 PM • 2 stops
Jacksonville → St Louis
23h 52m
5:06 PM - 8:38 AM • 2 stops
Frontier Airlines
Looking for the fastest way to St Louis? These direct flight options from JAX to STL offer both convenience and value—no layovers, just straight to your destination.
Jun 27 - Jul 04, Economy
Jacksonville → St Louis
3h 30m
6:20 PM - 7:30 PM • nonstop
Jacksonville → St Louis
3h 20m
8:30 AM - 11:30 AM • nonstop
Southwest Airlines
Jun 27 - Jul 04, Economy
Jacksonville → St Louis
3h 30m
8:25 AM - 9:35 AM • nonstop
Jacksonville → St Louis
3h 20m
8:30 AM - 11:30 AM • nonstop
Southwest Airlines
FAQs on Jacksonville to St Louis Flights
What are the airports in Jacksonville?
JAX
What’s the most popular airline flying from JAX to STL?
The most popular airline flying from Jacksonville to St Louis are
Can I fly from JAX to STL non-stop?
Yes, you can fly JAX to STL non-stop on
Which airlines fly nonstop between Jacksonville and St Louis?
The non-stop flights between Jacksonville and St Louis are .
What’s the earliest departure time from JAX to STL Airport?
The earliest flight leaves JAX at 8:25 am and lands in STL - Lambert St Louis International
What are the airports in St Louis?
STL
Can I make changes to my Jacksonville to St Louis flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from JAX to STL?
Read the fare rules of the Jacksonville to St Louis air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Jacksonville and St Louis?
operate flights between Jacksonville and St Louis
How long does a flight from Jacksonville to St Louis take?
It takes approximately 2 hour to fly non-stop from JAX to STL, which is 753.22 miles by air.
Which airlines provide the cheapest flights from Jacksonville (JAX) to St Louis (STL) ?
In the past couple of days, the cheapest tickets to STL from JAX were found on WN : USD 608
Do I need a passport to fly between JAX and STL?
No
What’s the latest departure time from JAX to STL ?
The last flight leaves JAX at 9:44 pm
Jacksonville (JAX) to St Louis (STL): Airport Information
| Origin Airport | Jacksonville International , Jacksonville, US |
| Destination Airport | Lambert St Louis International , St Louis, US |
| Distance | 753 miles |
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