Lowest Prices
Uncover the best deals on Detroit to St Louis flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest DTW - STL Flights
Useful information for finding best airline tickets from Detroit Metropolitan Wayne County to Lambert St Louis International on your next trip.
Cheapest Round Trip Flight
$158
Southwest Airlines
• nonstop
• 2h 15m
Sep 02 – Sep 10
The cheapest round trip flight from Detroit to St Louis (DTW-STL-DTW) is currently $158
Cheapest Direct Flight
$158
Southwest Airlines
• nonstop
• 2h 15m
Sep 02
The cheapest nonstop flight from Detroit to St Louis (DTW-STL) is currently $158
Fastest Flight
2h 15m
The fastest nonstop flight from Detroit to St Louis (DTW-STL) takes 2h 15m
Latest Flight Deals from Detroit (DTW) to St Louis (STL)
Compare and book low fare round-trip air tickets from Detroit to St Louis. Ideal for travelers with confirmed return itineraries.
Sep 02 - Sep 10, Economy
Detroit → St Louis
2h 15m
3:35 PM - 4:10 PM • nonstop
Detroit → St Louis
2h 10m
10:10 AM - 12:40 PM • nonstop
Southwest Airlines
Sep 02 - Sep 10, Economy
Detroit → St Louis
5h 15m
12:55 PM - 3:10 PM • 1 stop
Detroit → St Louis
5h 25m
6:05 AM - 10:30 AM • 1 stop
Southwest Airlines
Sep 02 - Sep 10, Economy
Detroit → St Louis
2h 18m
4:00 PM - 4:38 PM • nonstop
Detroit → St Louis
8h 27m
5:46 PM - 11:53 PM • 1 stop
Delta Airlines
Sep 02 - Sep 10, Economy
Detroit → St Louis
8h 34m
12:30 PM - 4:44 PM • 1 stop
Detroit → St Louis
2h 13m
6:40 AM - 9:13 AM • nonstop
Delta Airlines
Sep 02 - Sep 10, Economy
Detroit → St Louis
8h 23m
10:30 AM - 2:33 PM • 1 stop
Detroit → St Louis
2h 13m
6:40 AM - 9:13 AM • nonstop
Delta Airlines
Flying to St Louis soon? We've surfaced some of the most affordable last-minute flights from Detroit to St Louis, ideal for urgent plans or spontaneous trips.
Jul 17 - Jul 19, Economy
Detroit → St Louis
8h 50m
- • 1 stop
Detroit → St Louis
8h 40m
- • 1 stop
Southwest Airlines
Jul 17 - Jul 19, Economy
Detroit → St Louis
9h 6m
7:58 AM - 12:44 PM • 1 stop
Detroit → St Louis
6h 51m
6:55 AM - 12:06 PM • 1 stop
American Airlines
Jul 17 - Jul 19, Economy
Detroit → St Louis
8h 24m
- • 1 stop
Detroit → St Louis
10h 7m
- • 1 stop
United Airlines
Jul 17 - Jul 19, Economy
Detroit → St Louis
8h 29m
- • 1 stop
Detroit → St Louis
10h 7m
- • 1 stop
United Airlines
Jul 17 - Jul 19, Economy
Detroit → St Louis
23h 33m
6:10 AM - 7:23 PM • 2 stops
Detroit → St Louis
48h 26m
6:34 PM - 12:40 AM • 1 stop
Frontier Airlines
Looking for the fastest way to St Louis? These direct flight options from DTW to STL offer both convenience and value—no layovers, just straight to your destination.
Sep 02 - Sep 10, Economy
Detroit → St Louis
2h 15m
3:35 PM - 4:10 PM • nonstop
Detroit → St Louis
2h 10m
10:10 AM - 12:40 PM • nonstop
Southwest Airlines
Sep 02 - Sep 10, Economy
Detroit → St Louis
2h 15m
6:25 AM - 7:00 AM • nonstop
Detroit → St Louis
2h 10m
10:10 AM - 12:40 PM • nonstop
Southwest Airlines
Jul 17 - Jul 19, Economy
Detroit → St Louis
2h 15m
8:15 PM - 8:50 PM • nonstop
Detroit → St Louis
2h 10m
11:30 AM - 2:00 PM • nonstop
Southwest Airlines
Sep 02 - Sep 10, Economy
Detroit → St Louis
2h 18m
4:00 PM - 4:38 PM • nonstop
Detroit → St Louis
2h 13m
6:40 AM - 9:13 AM • nonstop
Delta Airlines
Sep 02 - Sep 10, Economy
Detroit → St Louis
2h 17m
9:00 AM - 9:37 AM • nonstop
Detroit → St Louis
2h 13m
6:40 AM - 9:13 AM • nonstop
Delta Airlines
FAQs on Detroit to St Louis Flights
What are the airports in Detroit?
DTW
What’s the most popular airline flying from DTW to STL?
The most popular airline flying from Detroit to St Louis are
Can I fly from DTW to STL non-stop?
Yes, you can fly DTW to STL non-stop on
Which airlines fly nonstop between Detroit and St Louis?
The non-stop flights between Detroit and St Louis are .
What’s the earliest departure time from DTW to STL Airport?
The earliest flight leaves DTW at 6:10 am and lands in STL - Lambert St Louis International
What are the airports in St Louis?
STL
Can I make changes to my Detroit to St Louis flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from DTW to STL?
Read the fare rules of the Detroit to St Louis air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Detroit and St Louis?
operate flights between Detroit and St Louis
How long does a flight from Detroit to St Louis take?
It takes approximately 1 hour to fly non-stop from DTW to STL, which is 439.98 miles by air.
Which airlines provide the cheapest flights from Detroit (DTW) to St Louis (STL) ?
In the past couple of days, the cheapest tickets to STL from DTW were found on DL : USD 260
Do I need a passport to fly between DTW and STL?
No
What’s the latest departure time from DTW to STL ?
The last flight leaves DTW at 6:2000 pm
Detroit (DTW) to St Louis (STL): Airport Information
| Origin Airport | Detroit Metropolitan Wayne County , Detroit, US |
| Destination Airport | Lambert St Louis International , St Louis, US |
| Distance | 440 miles |
More Flight Options for Detroit (DTW) and St Louis (STL)
Flights from Detroit (DTW)
to Las Vegas (LAS)
Flights from Detroit (DTW)
to Orlando (MCO)
Flights from Detroit (DTW)
to Los Angeles (LAX)
Flights from Detroit (DTW)
to New York (LGA)
Flights from Detroit (DTW)
to Philadelphia (PHL)
Flights from Detroit (DTW)
to Tampa (TPA)
Flights from Detroit (DTW)
to Boston (BOS)
Flights from Detroit (DTW)
to Charlotte (CLT)
Flights from Detroit (DTW)
to Fort Myers (RSW)
Flights from Detroit (DTW)
to Cancún (CUN)
Flights from Detroit (DTW)
to Norfolk (ORF)
Flights from Detroit (DTW)
to Miami (MIA)
Flights from Detroit (DTW)
to Ontario (ONT)
Flights from Detroit (DTW)
to Ontario (ONT)
Flights from Detroit (DTW)
to Myrtle Beach (MYR)
Flights from Detroit (DTW)
to San Francisco (SFO)
Flights from Detroit (DTW)
to Hartford (BDL)
Flights from Detroit (DTW)
to Hartford (BDL)
Flights from Detroit (DTW)
to Fort Lauderdale (FLL)
Flights from Detroit (DTW)
to Atlanta (ATL)
Flights from Denver (DEN)
to St Louis (STL)
Flights from Orlando (MCO)
to St Louis (STL)
Flights from El Paso (ELP)
to St Louis (STL)
Flights from Minneapolis (MSP)
to St Louis (STL)
Flights from Minneapolis (MSP)
to St Louis (STL)
Flights from Sacramento (SMF)
to St Louis (STL)
Flights from Houston (IAH)
to St Louis (STL)
Flights from San Francisco (SFO)
to St Louis (STL)
Flights from Jacksonville (JAX)
to St Louis (STL)
Flights from Tampa (TPA)
to St Louis (STL)
Flights from San Diego (SAN)
to St Louis (STL)
Flights from Omaha (OMA)
to St Louis (STL)
Flights from Dallas (DFW)
to St Louis (STL)
Flights from Charleston (CHS)
to St Louis (STL)
Flights from Dallas (DAL)
to St Louis (STL)
Flights from Phoenix (PHX)
to St Louis (STL)
Flights from Las Vegas (LAS)
to St Louis (STL)
Flights from Ontario (ONT)
to St Louis (STL)
Flights from Ontario (ONT)
to St Louis (STL)
Flights from Knoxville (TYS)
to St Louis (STL)
Cheap flights to North America (NA)
Cheap flights to United States (US)
Cheap flights to Missouri (US-MO)
Cheap flights to Michigan (US-MI)
Cheap flights from North America (NA)
Cheap flights from United States (US)
Cheap flights from Michigan (US-MI)
Cheap flights from Missouri (US-MO)
Flights to Detroit (DTW)
Flights to St Louis (STL)
Flights from Detroit (DTW)
Flights from St Louis (STL)
Flights from St Louis (STL)
to Detroit (DTW)
Why Fareleaders for DTW to STL Plane Tickets
New Deals Everyday
Get the best prices on DTW to STL flights—we update our fares daily so you never miss a saving.
No Service Fees
Compare hundreds of Detroit to St Louis flights and secure the best deals—we never add any service fees.