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Uncover the best deals on Detroit to St Louis flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest DTW - STL Flights
Useful information for finding best airline tickets from Detroit Metropolitan Wayne County to Lambert St Louis International on your next trip.
Cheapest Round Trip Flight
$269
Southwest Airlines
• nonstop
• 2h 15m
Sep 09 – Sep 12
The cheapest round trip flight from Detroit to St Louis (DTW-STL-DTW) is currently $269
Cheapest Direct Flight
$269
Southwest Airlines
• nonstop
• 2h 15m
Sep 09
The cheapest nonstop flight from Detroit to St Louis (DTW-STL) is currently $269
Fastest Flight
2h 15m
The fastest nonstop flight from Detroit to St Louis (DTW-STL) takes 2h 15m
Top Airlines Flying from Detroit to St Louis
Latest Flight Deals from Detroit (DTW) to St Louis (STL)
Compare and book low fare round-trip air tickets from Detroit to St Louis. Ideal for travelers with confirmed return itineraries.
Sep 09 - Sep 12, Economy
Detroit → St Louis
2h 15m
3:35 PM - 4:10 PM • nonstop
Detroit → St Louis
2h 15m
4:25 PM - 7:00 PM • nonstop
Southwest Airlines
Sep 09 - Sep 12, Economy
Detroit → St Louis
2h 15m
6:25 AM - 7:00 AM • nonstop
Detroit → St Louis
10h 5m
8:55 AM - 4:00 PM • 1 stop
Southwest Airlines
Sep 09 - Sep 12, Economy
Detroit → St Louis
8h 50m
5:35 AM - 10:05 AM • 1 stop
Detroit → St Louis
5h 30m
5:45 AM - 10:15 AM • 1 stop
Southwest Airlines
Sep 09 - Sep 12, Economy
Detroit → St Louis
10h 12m
7:20 AM - 12:32 PM • 1 stop
Detroit → St Louis
2h 13m
6:40 AM - 9:13 AM • nonstop
Delta Airlines
Sep 09 - Sep 12, Economy
Detroit → St Louis
6h 58m
7:05 AM - 10:23 AM • 1 stop
Detroit → St Louis
6h 59m
6:00 AM - 11:19 AM • 1 stop
Delta Airlines
Looking for the fastest way to St Louis? These direct flight options from DTW to STL offer both convenience and value—no layovers, just straight to your destination.
Sep 09 - Sep 12, Economy
Detroit → St Louis
2h 15m
3:35 PM - 4:10 PM • nonstop
Detroit → St Louis
2h 15m
4:25 PM - 7:00 PM • nonstop
Southwest Airlines
Sep 09 - Sep 12, Economy
Detroit → St Louis
2h 15m
6:25 AM - 7:00 AM • nonstop
Detroit → St Louis
2h 10m
10:15 AM - 12:45 PM • nonstop
Southwest Airlines
Sep 09 - Sep 12, Economy
Detroit → St Louis
2h 19m
8:50 AM - 9:29 AM • nonstop
Detroit → St Louis
2h 12m
4:10 PM - 6:42 PM • nonstop
Delta Airlines
Sep 09 - Sep 12, Economy
Detroit → St Louis
2h 17m
7:58 PM - 8:35 PM • nonstop
Detroit → St Louis
2h 13m
6:40 AM - 9:13 AM • nonstop
Delta Airlines
Sep 09 - Sep 12, Economy
Detroit → St Louis
2h 19m
2:35 PM - 3:14 PM • nonstop
Detroit → St Louis
2h 13m
10:29 AM - 1:02 PM • nonstop
Delta Airlines
FAQs on Detroit to St Louis Flights
What are the airports in Detroit?
DTW
What’s the most popular airline flying from DTW to STL?
The most popular airline flying from Detroit to St Louis are
Can I fly from DTW to STL non-stop?
Yes, you can fly DTW to STL non-stop on
Which airlines fly nonstop between Detroit and St Louis?
The non-stop flights between Detroit and St Louis are .
What’s the earliest departure time from DTW to STL Airport?
The earliest flight leaves DTW at 5:35 am and lands in STL - Lambert St Louis International
What are the airports in St Louis?
STL
Can I make changes to my Detroit to St Louis flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from DTW to STL?
Read the fare rules of the Detroit to St Louis air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Detroit and St Louis?
operate flights between Detroit and St Louis
How long does a flight from Detroit to St Louis take?
It takes approximately 1 hour to fly non-stop from DTW to STL, which is 439.98 miles by air.
Which airlines provide the cheapest flights from Detroit (DTW) to St Louis (STL) ?
In the past couple of days, the cheapest tickets to STL from DTW were found on DL : USD 388
Do I need a passport to fly between DTW and STL?
No
What’s the latest departure time from DTW to STL ?
The last flight leaves DTW at 7:58 pm
Detroit (DTW) to St Louis (STL): Airport Information
| Origin Airport | Detroit Metropolitan Wayne County , Detroit, US |
| Destination Airport | Lambert St Louis International , St Louis, US |
| Distance | 440 miles |
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