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Uncover the best deals on Detroit to St Louis flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest DTW - STL Flights
Useful information for finding best airline tickets from Detroit Metropolitan Wayne County to Lambert St Louis International on your next trip.
Cheapest Round Trip Flight
$469
United Airlines
• 1 stop
• 7h 19m
Aug 27 – Aug 29
The cheapest round trip flight from Detroit to St Louis (DTW-STL-DTW) is currently $469
Cheapest Direct Flight
$384
Southwest Airlines
• nonstop
• 2h 10m
Aug 27
The cheapest nonstop flight from Detroit to St Louis (DTW-STL) is currently $384
Fastest Flight
2h 10m
The fastest nonstop flight from Detroit to St Louis (DTW-STL) takes 2h 10m
Top Airlines Flying from Detroit to St Louis
Latest Flight Deals from Detroit (DTW) to St Louis (STL)
Compare and book low fare round-trip air tickets from Detroit to St Louis. Ideal for travelers with confirmed return itineraries.
Aug 27 - Aug 29, Economy
Detroit → St Louis
7h 19m
6:00 AM - 9:39 AM • 1 stop
Detroit → St Louis
6h 40m
6:54 PM - 11:54 PM • 1 stop
United Airlines
Aug 27 - Aug 29, Economy
Detroit → St Louis
5h 50m
4:26 PM - 7:16 PM • 1 stop
Detroit → St Louis
7h 11m
8:40 AM - 2:11 PM • 1 stop
United Airlines
Aug 27 - Aug 29, Economy
Detroit → St Louis
6h 43m
12:35 PM - 3:38 PM • 1 stop
Detroit → St Louis
5h 55m
5:30 PM - 10:25 PM • 1 stop
United Airlines
Aug 27 - Aug 29, Economy
Detroit → St Louis
2h 17m
9:00 AM - 9:37 AM • nonstop
Detroit → St Louis
2h 14m
6:30 AM - 9:04 AM • nonstop
Delta Airlines
Aug 27 - Aug 29, Economy
Detroit → St Louis
7h 14m
6:20 AM - 9:54 AM • 1 stop
Detroit → St Louis
2h 15m
6:09 PM - 8:44 PM • nonstop
Delta Airlines
Flying to St Louis soon? We've surfaced some of the most affordable last-minute flights from Detroit to St Louis, ideal for urgent plans or spontaneous trips.
Aug 27 - Aug 29, Economy
Detroit → St Louis
7h 19m
6:00 AM - 9:39 AM • 1 stop
Detroit → St Louis
6h 40m
6:54 PM - 11:54 PM • 1 stop
United Airlines
Aug 27 - Aug 29, Economy
Detroit → St Louis
5h 50m
4:26 PM - 7:16 PM • 1 stop
Detroit → St Louis
7h 11m
8:40 AM - 2:11 PM • 1 stop
United Airlines
Aug 27 - Aug 29, Economy
Detroit → St Louis
6h 43m
12:35 PM - 3:38 PM • 1 stop
Detroit → St Louis
5h 55m
5:30 PM - 10:25 PM • 1 stop
United Airlines
Aug 27 - Aug 29, Economy
Detroit → St Louis
2h 17m
9:00 AM - 9:37 AM • nonstop
Detroit → St Louis
2h 14m
6:30 AM - 9:04 AM • nonstop
Delta Airlines
Aug 27 - Aug 29, Economy
Detroit → St Louis
7h 14m
6:20 AM - 9:54 AM • 1 stop
Detroit → St Louis
2h 15m
6:09 PM - 8:44 PM • nonstop
Delta Airlines
Looking for the fastest way to St Louis? These direct flight options from DTW to STL offer both convenience and value—no layovers, just straight to your destination.
Aug 27 - Aug 29, Economy
Detroit → St Louis
2h 10m
2:40 PM - 3:10 PM • nonstop
Detroit → St Louis
2h 10m
4:25 PM - 6:55 PM • nonstop
Southwest Airlines
Aug 27 - Aug 29, Economy
Detroit → St Louis
2h 30m
6:55 AM - 7:45 AM • nonstop
Detroit → St Louis
2h 10m
10:15 AM - 12:45 PM • nonstop
Southwest Airlines
Aug 27 - Aug 29, Economy
Detroit → St Louis
2h 17m
9:00 AM - 9:37 AM • nonstop
Detroit → St Louis
2h 14m
6:30 AM - 9:04 AM • nonstop
Delta Airlines
Aug 27 - Aug 29, Economy
Detroit → St Louis
2h 17m
8:05 PM - 8:42 PM • nonstop
Detroit → St Louis
2h 15m
6:09 PM - 8:44 PM • nonstop
Delta Airlines
Aug 27 - Aug 29, Economy
Detroit → St Louis
2h 18m
12:36 PM - 1:14 PM • nonstop
Detroit → St Louis
2h 15m
6:09 PM - 8:44 PM • nonstop
Delta Airlines
FAQs on Detroit to St Louis Flights
What are the airports in Detroit?
DTW
What’s the most popular airline flying from DTW to STL?
The most popular airline flying from Detroit to St Louis are
Can I fly from DTW to STL non-stop?
Yes, you can fly DTW to STL non-stop on
Which airlines fly nonstop between Detroit and St Louis?
The non-stop flights between Detroit and St Louis are .
What’s the earliest departure time from DTW to STL Airport?
The earliest flight leaves DTW at 6:00 am and lands in STL - Lambert St Louis International
What are the airports in St Louis?
STL
Can I make changes to my Detroit to St Louis flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from DTW to STL?
Read the fare rules of the Detroit to St Louis air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Detroit and St Louis?
operate flights between Detroit and St Louis
How long does a flight from Detroit to St Louis take?
It takes approximately 1 hour to fly non-stop from DTW to STL, which is 439.98 miles by air.
Which airlines provide the cheapest flights from Detroit (DTW) to St Louis (STL) ?
In the past couple of days, the cheapest tickets to STL from DTW were found on DL : USD 983
Do I need a passport to fly between DTW and STL?
No
What’s the latest departure time from DTW to STL ?
The last flight leaves DTW at 8:05 pm
Detroit (DTW) to St Louis (STL): Airport Information
| Origin Airport | Detroit Metropolitan Wayne County , Detroit, US |
| Destination Airport | Lambert St Louis International , St Louis, US |
| Distance | 440 miles |
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