Cheap Flight Tickets from Fort Myers (RSW) to San Diego (SAN), Starting at $385

Good to Know: Cheapest and Fastest RSW - SAN Flights

Useful information for finding best airline tickets from Southwest Florida International to San Diego International on your next trip.

Cheapest Round Trip Flight

$385

F9 Frontier Airlines • 1 stop • 42h 26m

Nov 22 – Nov 27

The cheapest round trip flight from Fort Myers to San Diego (RSW-SAN-RSW) is currently $385

🔍 Search Flights

Fastest Flight

17h 15m

The fastest nonstop flight from Fort Myers to San Diego (RSW-SAN) takes 17h 15m

Top Airlines Flying from Fort Myers to San Diego

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

Sun Country Airlines (SY)

Sun Country Airlines

American Airlines, AA

American Airlines

Alaska Airlines -AS

Alaska Airlines

Latest Flight Deals from Fort Myers (RSW) to San Diego (SAN)

Compare and book low fare round-trip air tickets from Fort Myers to San Diego. Ideal for travelers with confirmed return itineraries.

Nov 22 - Nov 27, Economy
F9
Fort Myers → San Diego
42h 26m
5:48 PM - 4:34 PM • 1 stop
F9
Fort Myers → San Diego
12h 3m
6:30 AM - 4:53 PM • 1 stop
$385
Frontier Airlines
Nov 22 - Nov 27, Economy
WN
Fort Myers → San Diego
18h 40m
3:00 PM - 11:20 PM • 1 stop
WN
Fort Myers → San Diego
13h 45m
12:10 PM - 11:35 PM • 2 stops
$514
Southwest Airlines
Nov 22 - Nov 27, Economy
WN
Fort Myers → San Diego
22h
8:25 AM - 6:45 PM • 1 stop
WN
Fort Myers → San Diego
13h 45m
12:10 PM - 11:35 PM • 2 stops
$514
Southwest Airlines
Nov 23 - Nov 28, Economy
WN
Fort Myers → San Diego
25h
6:20 AM - 6:20 PM • 1 stop
WN
Fort Myers → San Diego
15h 5m
6:35 AM - 6:40 PM • 1 stop
$561
Southwest Airlines
Nov 23 - Nov 28, Economy
WN
Fort Myers → San Diego
17h 15m
4:50 PM - 12:25 AM • 1 stop
WN
Fort Myers → San Diego
15h 45m
10:40 PM - 11:25 AM • 2 stops
$589
Southwest Airlines
Nov 23 - Nov 28, Economy
AS
Fort Myers → San Diego
50h 7m
8:30 AM - 8:26 PM • 2 stops
AS
Fort Myers → San Diego
40h 56m
6:15 AM - 9:00 PM • 1 stop
$1070
Alaska Airlines

Fly from Fort Myers to San Diego with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Fort Myers to San Diego? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Fort Myers to San Diego Flights

What are the airports in Fort Myers?
RSW
What’s the most popular airline flying from RSW to SAN?
The most popular airline flying from Fort Myers to San Diego are
Can I fly from RSW to SAN non-stop?
NO
Which airlines fly nonstop between Fort Myers and San Diego?
The non-stop flights between Fort Myers and San Diego are .
What’s the earliest departure time from RSW to SAN Airport?
The earliest flight leaves RSW at 6:20 am and lands in SAN - San Diego International
What are the airports in San Diego?
SAN
Can I make changes to my Fort Myers to San Diego flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from RSW to SAN?
Read the fare rules of the Fort Myers to San Diego air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Fort Myers and San Diego?
operate flights between Fort Myers and San Diego
How long does a flight from Fort Myers to San Diego take?
It takes approximately 5 hour to fly non-stop from RSW to SAN, which is 2164.08 miles by air.
Which airlines provide the cheapest flights from Fort Myers (RSW) to San Diego (SAN) ?
In the past couple of days, the cheapest tickets to SAN from RSW were found on WN : USD 514
Do I need a passport to fly between RSW and SAN?
No
What’s the latest departure time from RSW to SAN ?
The last flight leaves RSW at 5:48 pm

Fort Myers (RSW) to San Diego (SAN): Airport Information

Origin Airport Southwest Florida International , Fort Myers, US
Destination Airport San Diego International , San Diego, US
Distance 2164 miles

More Flight Options for Fort Myers (RSW) and San Diego (SAN)

Why Fareleaders for RSW to SAN Plane Tickets

Lowest Prices
Lowest Prices
Uncover the best deals on Fort Myers to San Diego flights by comparing fares from hundreds of airlines and agencies.
New Deals
New Deals Everyday
Get the best prices on RSW to SAN flights—we update our fares daily so you never miss a saving.
Best Travel Options
No Service Fees
Compare hundreds of Fort Myers to San Diego flights and secure the best deals—we never add any service fees.
Get Fare Drop Alert
Be the first to know when fares drop for the Fort Myers (RSW) to San Diego (SAN)
Terms and Conditions*