Cheap Flight Tickets from Des Moines (DSM) to St Louis (STL), Starting at $127

Good to Know: Cheapest and Fastest DSM - STL Flights

Useful information for finding best airline tickets from Des Moines International to Lambert St Louis International on your next trip.

Cheapest Round Trip Flight

$127

WN Southwest Airlines • 2 stops • 23h 30m

Sep 17 – Sep 24

The cheapest round trip flight from Des Moines to St Louis (DSM-STL-DSM) is currently $127

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Fastest Flight

33m

The fastest nonstop flight from Des Moines to St Louis (DSM-STL) takes 33m

Top Airlines Flying from Des Moines to St Louis

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Latest Flight Deals from Des Moines (DSM) to St Louis (STL)

Compare and book low fare round-trip air tickets from Des Moines to St Louis. Ideal for travelers with confirmed return itineraries.

Sep 17 - Sep 24, Economy
WN
Des Moines → St Louis
23h 30m
- • 2 stops
WN
Des Moines → St Louis
10h 55m
- • 2 stops
$127
Southwest Airlines
Sep 17 - Sep 24, Economy
DL
Des Moines → St Louis
11h 46m
- • 1 stop
AA
Des Moines → St Louis
10h 25m
- • 1 stop
$144
Delta Airlines
Sep 17 - Sep 24, Economy
AA
Des Moines → St Louis
28h 38m
- • 1 stop
WN
Des Moines → St Louis
10h 55m
- • 2 stops
$171
American Airlines
Sep 17 - Sep 24, Economy
AA
Des Moines → St Louis
16h 49m
- • 1 stop
AA
Des Moines → St Louis
10h 25m
- • 1 stop
$181
American Airlines
Sep 17 - Sep 24, Economy
WN
Des Moines → St Louis
33m
5:40 AM - 4:45 PM • 2 stops
WN
Des Moines → St Louis
20m
3:15 PM - 10:10 PM • 2 stops
$241
Southwest Airlines
Sep 17 - Sep 24, Economy
DL
Des Moines → St Louis
10h 50m
10:10 AM - 5:00 PM • 1 stop
DL
Des Moines → St Louis
8h 47m
4:49 PM - 10:16 PM • 1 stop
$398
Delta Airlines

Fly from Des Moines to St Louis with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Des Moines to St Louis? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Des Moines to St Louis Flights

What are the airports in Des Moines?
DSM
What’s the most popular airline flying from DSM to STL?
The most popular airline flying from Des Moines to St Louis are
Can I fly from DSM to STL non-stop?
NO
Which airlines fly nonstop between Des Moines and St Louis?
The non-stop flights between Des Moines and St Louis are .
What’s the earliest departure time from DSM to STL Airport?
The earliest flight leaves DSM at 5:40 am and lands in STL - Lambert St Louis International
What are the airports in St Louis?
STL
Can I make changes to my Des Moines to St Louis flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from DSM to STL?
Read the fare rules of the Des Moines to St Louis air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Des Moines and St Louis?
operate flights between Des Moines and St Louis
How long does a flight from Des Moines to St Louis take?
It takes approximately 1 hour to fly non-stop from DSM to STL, which is 259.45 miles by air.
Which airlines provide the cheapest flights from Des Moines (DSM) to St Louis (STL) ?
In the past couple of days, the cheapest tickets to STL from DSM were found on DL : USD 398
Do I need a passport to fly between DSM and STL?
No
What’s the latest departure time from DSM to STL ?
The last flight leaves DSM at 7:5800 pm

Des Moines (DSM) to St Louis (STL): Airport Information

Origin Airport Des Moines International , Des Moines, US
Destination Airport Lambert St Louis International , St Louis, US
Distance 259 miles

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