Lowest Prices
Uncover the best deals on Chicago to Des Moines flights by comparing fares from hundreds of airlines and agencies.
Useful information for finding best airline tickets from Chicago Midway International to Des Moines International on your next trip.
Cheapest Round Trip Flight
$244
Southwest Airlines
• nonstop
• 2h 5m
Nov 14 – Nov 15
The cheapest round trip flight from Chicago to Des Moines (MDW-DSM-MDW) is currently $244
Cheapest Direct Flight
$191
Southwest Airlines
• nonstop
• 2h 5m
Nov 16
The cheapest nonstop flight from Chicago to Des Moines (MDW-DSM) is currently $191
Fastest Flight
2h
The fastest nonstop flight from Chicago to Des Moines (MDW-DSM) takes 2h
| Origin Airport | Chicago Midway International , Chicago, US |
| Destination Airport | Des Moines International , Des Moines, US |
| Distance | 306 miles |