Lowest Prices
Uncover the best deals on Buffalo to Santa Ana flights by comparing fares from hundreds of airlines and agencies.
Useful information for finding best airline tickets from Buffalo Niagara International to John Wayne -Orange County on your next trip.
Cheapest Round Trip Flight
$113
Southwest Airlines
• 1 stop
• 15h 15m
Nov 02 – Nov 09
The cheapest round trip flight from Buffalo to Santa Ana (BUF-SNA-BUF) is currently $113
Fastest Flight
10h 24m
The fastest nonstop flight from Buffalo to Santa Ana (BUF-SNA) takes 10h 24m
| Origin Airport | Buffalo Niagara International , Buffalo, US |
| Destination Airport | John Wayne -Orange County , Santa Ana, US |
| Distance | 2199 miles |