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Uncover the best deals on San Diego to St Louis flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest SAN - STL Flights
Useful information for finding best airline tickets from San Diego International to Lambert St Louis International on your next trip.
Cheapest Round Trip Flight
$263
American Airlines
• 1 stop
• 10h 28m
Jul 22 – Aug 10
The cheapest round trip flight from San Diego to St Louis (SAN-STL-SAN) is currently $263
Cheapest Direct Flight
$246
Southwest Airlines
• nonstop
• 5h 35m
Aug 06
The cheapest nonstop flight from San Diego to St Louis (SAN-STL) is currently $246
Fastest Flight
5h 35m
The fastest nonstop flight from San Diego to St Louis (SAN-STL) takes 5h 35m
Top Airlines Flying from San Diego to St Louis
Latest Flight Deals from San Diego (SAN) to St Louis (STL)
Compare and book low fare round-trip air tickets from San Diego to St Louis. Ideal for travelers with confirmed return itineraries.
Jul 22 - Aug 10, Economy
San Diego → St Louis
10h 28m
8:00 AM - 4:28 PM • 1 stop
San Diego → St Louis
9h 13m
6:36 AM - 10:29 AM • 1 stop
American Airlines
Jul 21 - Aug 09, Economy
San Diego → St Louis
15h 39m
7:18 AM - 6:57 PM • 1 stop
San Diego → St Louis
9h 5m
8:00 AM - 11:45 AM • 1 stop
American Airlines
Jul 22 - Aug 10, Economy
San Diego → St Louis
14h 10m
7:50 AM - 6:40 PM • 1 stop
San Diego → St Louis
13h 30m
3:45 PM - 9:55 PM • 1 stop
Southwest Airlines
Jul 22 - Aug 10, Economy
San Diego → St Louis
9h
5:01 PM - 12:41 AM • 1 stop
San Diego → St Louis
11h 59m
3:39 PM - 8:58 PM • 1 stop
Delta Airlines
Jul 22 - Aug 10, Economy
San Diego → St Louis
5h 40m
7:05 AM - 12:45 PM • nonstop
San Diego → St Louis
8h 30m
3:45 PM - 6:55 PM • 1 stop
Southwest Airlines
Flying to St Louis soon? We've surfaced some of the most affordable last-minute flights from San Diego to St Louis, ideal for urgent plans or spontaneous trips.
Jul 22 - Aug 10, Economy
San Diego → St Louis
10h 28m
8:00 AM - 4:28 PM • 1 stop
San Diego → St Louis
9h 13m
6:36 AM - 10:29 AM • 1 stop
American Airlines
Jul 21 - Aug 09, Economy
San Diego → St Louis
15h 39m
7:18 AM - 6:57 PM • 1 stop
San Diego → St Louis
9h 5m
8:00 AM - 11:45 AM • 1 stop
American Airlines
Jul 22 - Aug 10, Economy
San Diego → St Louis
14h 10m
7:50 AM - 6:40 PM • 1 stop
San Diego → St Louis
13h 30m
3:45 PM - 9:55 PM • 1 stop
Southwest Airlines
Jul 22 - Aug 10, Economy
San Diego → St Louis
9h
5:01 PM - 12:41 AM • 1 stop
San Diego → St Louis
11h 59m
3:39 PM - 8:58 PM • 1 stop
Delta Airlines
Jul 22 - Aug 10, Economy
San Diego → St Louis
5h 40m
7:05 AM - 12:45 PM • nonstop
San Diego → St Louis
8h 30m
3:45 PM - 6:55 PM • 1 stop
Southwest Airlines
Looking for the fastest way to St Louis? These direct flight options from SAN to STL offer both convenience and value—no layovers, just straight to your destination.
Aug 06 - Aug 17, Economy
San Diego → St Louis
5h 35m
12:25 PM - 6:00 PM • nonstop
San Diego → St Louis
5h 45m
8:35 AM - 10:20 AM • nonstop
Southwest Airlines
Jul 18 - Dec 05, Economy
San Diego → St Louis
5h 40m
6:30 AM - 12:10 PM • nonstop
San Diego → St Louis
5h 55m
3:05 PM - 5:00 PM • nonstop
Southwest Airlines
Jul 18 - Dec 05, Economy
San Diego → St Louis
5h 40m
12:20 PM - 6:00 PM • nonstop
San Diego → St Louis
5h 55m
3:05 PM - 5:00 PM • nonstop
Southwest Airlines
Jul 22 - Aug 10, Economy
San Diego → St Louis
5h 40m
7:05 AM - 12:45 PM • nonstop
San Diego → St Louis
5h 45m
8:35 AM - 10:20 AM • nonstop
Southwest Airlines
FAQs on San Diego to St Louis Flights
What are the airports in San Diego?
SAN
What’s the most popular airline flying from SAN to STL?
The most popular airline flying from San Diego to St Louis are
Can I fly from SAN to STL non-stop?
Yes, you can fly SAN to STL non-stop on
Which airlines fly nonstop between San Diego and St Louis?
The non-stop flights between San Diego and St Louis are .
What’s the earliest departure time from SAN to STL Airport?
The earliest flight leaves SAN at 6:30 am and lands in STL - Lambert St Louis International
What are the airports in St Louis?
STL
Can I make changes to my San Diego to St Louis flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from SAN to STL?
Read the fare rules of the San Diego to St Louis air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from San Diego and St Louis?
operate flights between San Diego and St Louis
How long does a flight from San Diego to St Louis take?
It takes approximately 4 hour to fly non-stop from SAN to STL, which is 1557.18 miles by air.
Which airlines provide the cheapest flights from San Diego (SAN) to St Louis (STL) ?
In the past couple of days, the cheapest tickets to STL from SAN were found on WN : USD 828
Do I need a passport to fly between SAN and STL?
No
What’s the latest departure time from SAN to STL ?
The last flight leaves SAN at 5:01 pm
San Diego (SAN) to St Louis (STL): Airport Information
| Origin Airport | San Diego International , San Diego, US |
| Destination Airport | Lambert St Louis International , St Louis, US |
| Distance | 1557 miles |
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