Lowest Prices
Uncover the best deals on Myrtle Beach to Buffalo flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest MYR - BUF Flights
Useful information for finding best airline tickets from Myrtle Beach International to Buffalo Niagara International on your next trip.
Cheapest Round Trip Flight
$230
Delta Airlines
• 1 stop
• 5h 46m
Oct 08 – Oct 11
The cheapest round trip flight from Myrtle Beach to Buffalo (MYR-BUF-MYR) is currently $230
Cheapest One way Flight
$133
Southwest Airlines
• 1 stop
• 5h 35m
Aug 21
The cheapest one way flight from Myrtle Beach to Buffalo (MYR-BUF) is currently $133
Fastest Flight
5h 35m
The fastest nonstop flight from Myrtle Beach to Buffalo (MYR-BUF) takes 5h 35m
Top Airlines Flying from Myrtle Beach to Buffalo
Latest Flight Deals from Myrtle Beach (MYR) to Buffalo (BUF)
Compare and book low fare round-trip air tickets from Myrtle Beach to Buffalo. Ideal for travelers with confirmed return itineraries.
Oct 08 - Oct 11, Economy
Myrtle Beach → Buffalo
5h 46m
11:27 AM - 3:13 PM • 1 stop
Myrtle Beach → Buffalo
7h 7m
6:15 AM - 10:42 AM • 1 stop
Delta Airlines
Oct 08 - Oct 11, Economy
Myrtle Beach → Buffalo
12h 35m
6:15 AM - 2:10 PM • 1 stop
Myrtle Beach → Buffalo
10h 25m
9:00 AM - 3:25 PM • 1 stop
Southwest Airlines
Oct 08 - Oct 11, Economy
Myrtle Beach → Buffalo
8h 35m
1:25 PM - 6:40 PM • 1 stop
Myrtle Beach → Buffalo
18h 45m
8:00 AM - 7:25 PM • 1 stop
Southwest Airlines
Oct 08 - Oct 11, Economy
Myrtle Beach → Buffalo
10h 40m
10:25 AM - 5:05 PM • 1 stop
Myrtle Beach → Buffalo
13h 55m
10:50 AM - 7:25 PM • 2 stops
Southwest Airlines
Oct 08 - Oct 11, Economy
Myrtle Beach → Buffalo
20h 32m
11:27 AM - 11:59 PM • 1 stop
Myrtle Beach → Buffalo
7h 7m
6:15 AM - 10:42 AM • 1 stop
Delta Airlines
Explore competitive one-way airfare options for MYR - BUF flights. Best suited for flexible or open-ended travel plans.
Flying to Buffalo soon? We've surfaced some of the most affordable last-minute flights from Myrtle Beach to Buffalo, ideal for urgent plans or spontaneous trips.
Aug 31 - Sep 07, Economy
Myrtle Beach → Buffalo
10h
10:50 AM - 4:50 PM • 1 stop
Myrtle Beach → Buffalo
9h 10m
11:45 AM - 5:35 PM • 1 stop
Southwest Airlines
Aug 31 - Sep 07, Economy
Myrtle Beach → Buffalo
12h 15m
10:50 AM - 6:25 PM • 2 stops
Myrtle Beach → Buffalo
5h 50m
3:55 PM - 7:45 PM • 1 stop
Southwest Airlines
Aug 31 - Sep 07, Economy
Myrtle Beach → Buffalo
12h 27m
6:00 AM - 1:47 PM • 2 stops
Myrtle Beach → Buffalo
6h 51m
6:27 AM - 10:38 AM • 1 stop
Delta Airlines
Aug 31 - Sep 07, Economy
Myrtle Beach → Buffalo
28h 49m
6:00 AM - 11:29 PM • 2 stops
Myrtle Beach → Buffalo
6h 51m
6:27 AM - 10:38 AM • 1 stop
Delta Airlines
Aug 31 - Sep 07, Economy
Myrtle Beach → Buffalo
31h 52m
4:10 PM - 11:22 AM • 2 stops
Myrtle Beach → Buffalo
6h 51m
6:27 AM - 10:38 AM • 1 stop
Delta Airlines
FAQs on Myrtle Beach to Buffalo Flights
What are the airports in Myrtle Beach?
MYR
What’s the most popular airline flying from MYR to BUF?
The most popular airline flying from Myrtle Beach to Buffalo are
Can I fly from MYR to BUF non-stop?
NO
Which airlines fly nonstop between Myrtle Beach and Buffalo?
The non-stop flights between Myrtle Beach and Buffalo are .
What’s the earliest departure time from MYR to BUF Airport?
The earliest flight leaves MYR at 6:00 am and lands in BUF - Buffalo Niagara International
What are the airports in Buffalo?
BUF
Can I make changes to my Myrtle Beach to Buffalo flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from MYR to BUF?
Read the fare rules of the Myrtle Beach to Buffalo air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Myrtle Beach and Buffalo?
operate flights between Myrtle Beach and Buffalo
How long does a flight from Myrtle Beach to Buffalo take?
It takes approximately 2 hour to fly non-stop from MYR to BUF, which is 638.84 miles by air.
Which airlines provide the cheapest flights from Myrtle Beach (MYR) to Buffalo (BUF) ?
In the past couple of days, the cheapest tickets to BUF from MYR were found on WN : USD 336
Do I need a passport to fly between MYR and BUF?
No
What’s the latest departure time from MYR to BUF ?
The last flight leaves MYR at 6:15 pm
Myrtle Beach (MYR) to Buffalo (BUF): Airport Information
| Origin Airport | Myrtle Beach International , Myrtle Beach, US |
| Destination Airport | Buffalo Niagara International , Buffalo, US |
| Distance | 639 miles |
More Flight Options for Myrtle Beach (MYR) and Buffalo (BUF)
Flights from Myrtle Beach (MYR)
to Hartford (BDL)
Flights from Myrtle Beach (MYR)
to New York (LGA)
Flights from Myrtle Beach (MYR)
to Las Vegas (LAS)
Flights from Myrtle Beach (MYR)
to Kansas City (MCI)
Flights from Myrtle Beach (MYR)
to Newark (EWR)
Flights from Myrtle Beach (MYR)
to Newark (EWR)
Flights from Myrtle Beach (MYR)
to Baltimore (BWI)
Flights from Myrtle Beach (MYR)
to Miami (MIA)
Flights from Myrtle Beach (MYR)
to Knoxville (TYS)
Flights from Myrtle Beach (MYR)
to Denver (DEN)
Flights from Myrtle Beach (MYR)
to Washington (DCA)
Flights from Myrtle Beach (MYR)
to Atlantic City (ACY)
Flights from Myrtle Beach (MYR)
to Harrisburg (MDT)
Flights from Myrtle Beach (MYR)
to Indianapolis (IND)
Flights from Myrtle Beach (MYR)
to Norfolk (ORF)
Flights from Myrtle Beach (MYR)
to Philadelphia (PHL)
Flights from Myrtle Beach (MYR)
to Pittsburgh (PIT)
Flights from Myrtle Beach (MYR)
to Buffalo (BUF)
Flights from Myrtle Beach (MYR)
to New York (JFK)
Flights from Myrtle Beach (MYR)
to Detroit (DTW)
Flights from Atlanta (ATL)
to Buffalo (BUF)
Flights from Tampa (TPA)
to Buffalo (BUF)
Flights from Washington (DCA)
to Buffalo (BUF)
Flights from San Diego (SAN)
to Buffalo (BUF)
Flights from Orlando (MCO)
to Buffalo (BUF)
Flights from Cincinnati (CVG)
to Buffalo (BUF)
Flights from Nashville (BNA)
to Buffalo (BUF)
Flights from Washington (IAD)
to Buffalo (BUF)
Flights from Jacksonville (JAX)
to Buffalo (BUF)
Flights from Seattle (SEA)
to Buffalo (BUF)
Flights from Columbus (CMH)
to Buffalo (BUF)
Flights from Charlotte (CLT)
to Buffalo (BUF)
Flights from Dallas (DFW)
to Buffalo (BUF)
Flights from Ontario (ONT)
to Buffalo (BUF)
Flights from Ontario (ONT)
to Buffalo (BUF)
Flights from St Louis (STL)
to Buffalo (BUF)
Flights from Fort Lauderdale (FLL)
to Buffalo (BUF)
Flights from Dallas (DAL)
to Buffalo (BUF)
Flights from New York (LGA)
to Buffalo (BUF)
Flights from Austin (AUS)
to Buffalo (BUF)
Cheap flights to North America (NA)
Cheap flights to United States (US)
Cheap flights to South Carolina (US-SC)
Cheap flights to New York (US-NY)
Cheap flights from North America (NA)
Cheap flights from United States (US)
Cheap flights from South Carolina (US-SC)
Cheap flights from New York (US-NY)
Flights to Buffalo (BUF)
Flights to Myrtle Beach (MYR)
Flights from Buffalo (BUF)
Flights from Buffalo (BUF)
to Myrtle Beach (MYR)
Flights from Myrtle Beach (MYR)
Why Fareleaders for MYR to BUF Plane Tickets
New Deals Everyday
Get the best prices on MYR to BUF flights—we update our fares daily so you never miss a saving.
No Service Fees
Compare hundreds of Myrtle Beach to Buffalo flights and secure the best deals—we never add any service fees.