Cheap Flight Tickets from Detroit (DTW) to Greenville (GSP), Starting at $390

Good to Know: Cheapest and Fastest DTW - GSP Flights

Useful information for finding best airline tickets from Detroit Metropolitan Wayne County to Greenville Spartanburg International on your next trip.

Cheapest Round Trip Flight

$390

WN Southwest Airlines • 1 stop • 17h 25m

Sep 15 – Sep 17

The cheapest round trip flight from Detroit to Greenville (DTW-GSP-DTW) is currently $390

🔍 Search Flights

Cheapest Direct Flight

$592

DL Delta Airlines • nonstop • 2h 29m

Sep 16

The cheapest nonstop flight from Detroit to Greenville (DTW-GSP) is currently $592

🔍 Search Flights

Fastest Flight

2h 21m

The fastest nonstop flight from Detroit to Greenville (DTW-GSP) takes 2h 21m

Latest Flight Deals from Detroit (DTW) to Greenville (GSP)

Compare and book low fare round-trip air tickets from Detroit to Greenville. Ideal for travelers with confirmed return itineraries.

Sep 15 - Sep 17, Economy
WN
Detroit → Greenville
17h 25m
6:00 AM - 4:45 PM • 1 stop
WN
Detroit → Greenville
5h 45m
6:55 PM - 10:40 PM • 1 stop
$390
Southwest Airlines
Sep 15 - Sep 17, Economy
WN
Detroit → Greenville
45h 50m
12:55 PM - 4:45 PM • 2 stops
WN
Detroit → Greenville
5h 45m
6:55 PM - 10:40 PM • 1 stop
$396
Southwest Airlines
Sep 15 - Sep 17, Economy
WN
Detroit → Greenville
35h 20m
12:55 PM - 10:15 AM • 2 stops
WN
Detroit → Greenville
5h 45m
6:55 PM - 10:40 PM • 1 stop
$401
Southwest Airlines
Sep 15 - Sep 17, Economy
WN
Detroit → Greenville
10h 25m
6:00 AM - 12:25 PM • 1 stop
WN
Detroit → Greenville
20h 15m
8:40 AM - 8:55 PM • 2 stops
$413
Southwest Airlines
Sep 15 - Sep 17, Economy
WN
Detroit → Greenville
25h
6:00 AM - 9:00 PM • 1 stop
WN
Detroit → Greenville
20h 15m
8:40 AM - 8:55 PM • 2 stops
$436
Southwest Airlines
Sep 15 - Sep 17, Economy
WN
Detroit → Greenville
17h 25m
6:00 AM - 4:45 PM • 1 stop
WN
Detroit → Greenville
23h 20m
8:40 AM - 10:40 PM • 3 stops
$437
Southwest Airlines

Fly from Detroit to Greenville with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from Detroit to Greenville? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on Detroit to Greenville Flights

What are the airports in Detroit?
DTW
What’s the most popular airline flying from DTW to GSP?
The most popular airline flying from Detroit to Greenville are
Can I fly from DTW to GSP non-stop?
Yes, you can fly DTW to GSP non-stop on
Which airlines fly nonstop between Detroit and Greenville?
The non-stop flights between Detroit and Greenville are .
What’s the earliest departure time from DTW to GSP Airport?
The earliest flight leaves DTW at 6:00 am and lands in GSP - Greenville Spartanburg International
What are the airports in Greenville?
GSP
Can I make changes to my Detroit to Greenville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from DTW to GSP?
Read the fare rules of the Detroit to Greenville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Detroit and Greenville?
operate flights between Detroit and Greenville
How long does a flight from Detroit to Greenville take?
It takes approximately 2 hour to fly non-stop from DTW to GSP, which is 508.39 miles by air.
Which airlines provide the cheapest flights from Detroit (DTW) to Greenville (GSP) ?
In the past couple of days, the cheapest tickets to GSP from DTW were found on WN : USD 413
Do I need a passport to fly between DTW and GSP?
No
What’s the latest departure time from DTW to GSP ?
The last flight leaves DTW at 7:4500 pm

Detroit (DTW) to Greenville (GSP): Airport Information

Origin Airport Detroit Metropolitan Wayne County , Detroit, US
Destination Airport Greenville Spartanburg International , Greenville, US
Distance 508 miles

More Flight Options for Detroit (DTW) and Greenville (GSP)

Why Fareleaders for DTW to GSP Plane Tickets

Lowest Prices
Lowest Prices
Uncover the best deals on Detroit to Greenville flights by comparing fares from hundreds of airlines and agencies.
New Deals
New Deals Everyday
Get the best prices on DTW to GSP flights—we update our fares daily so you never miss a saving.
Best Travel Options
No Service Fees
Compare hundreds of Detroit to Greenville flights and secure the best deals—we never add any service fees.
Get Fare Drop Alert
Be the first to know when fares drop for the Detroit (DTW) to Greenville (GSP)
Terms and Conditions*