Lowest Prices
Uncover the best deals on Detroit to Greenville flights by comparing fares from hundreds of airlines and agencies.
Useful information for finding best airline tickets from Detroit Metropolitan Wayne County to Greenville Spartanburg International on your next trip.
Cheapest One way Flight
$710
Delta Airlines
• 2 stops
• 18h 57m
Nov 12
The cheapest one way flight from Detroit to Greenville (DTW-GSP) is currently $710
Fastest Flight
12h 27m
The fastest nonstop flight from Detroit to Greenville (DTW-GSP) takes 12h 27m
| Origin Airport | Detroit Metropolitan Wayne County , Detroit, US |
| Destination Airport | Greenville Spartanburg International , Greenville, US |
| Distance | 508 miles |