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Uncover the best deals on Detroit to Greenville flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest DTW - GSP Flights
Useful information for finding best airline tickets from Detroit Metropolitan Wayne County to Greenville Spartanburg International on your next trip.
Cheapest Round Trip Flight
$379
American Airlines
• 1 stop
• 7h 3m
Sep 15 – Sep 18
The cheapest round trip flight from Detroit to Greenville (DTW-GSP-DTW) is currently $379
Cheapest Direct Flight
$933
Delta Airlines
• nonstop
• 2h 29m
Sep 14
The cheapest nonstop flight from Detroit to Greenville (DTW-GSP) is currently $933
Fastest Flight
2h 21m
The fastest nonstop flight from Detroit to Greenville (DTW-GSP) takes 2h 21m
Latest Flight Deals from Detroit (DTW) to Greenville (GSP)
Compare and book low fare round-trip air tickets from Detroit to Greenville. Ideal for travelers with confirmed return itineraries.
Sep 15 - Sep 18, Economy
Detroit → Greenville
7h 3m
6:00 AM - 10:23 AM • 1 stop
Detroit → Greenville
6h 57m
5:21 PM - 9:38 PM • 1 stop
American Airlines
Sep 14 - Sep 18, Economy
Detroit → Greenville
8h 49m
6:00 AM - 11:29 AM • 1 stop
Detroit → Greenville
5h 54m
1:36 PM - 5:30 PM • 1 stop
American Airlines
Sep 14 - Sep 18, Economy
Detroit → Greenville
2h 29m
4:28 PM - 6:17 PM • nonstop
Detroit → Greenville
6h 58m
7:00 AM - 11:18 AM • 1 stop
Delta Airlines
Sep 14 - Sep 18, Economy
Detroit → Greenville
2h 34m
8:30 AM - 10:24 AM • nonstop
Detroit → Greenville
7h 15m
5:45 AM - 10:20 AM • 1 stop
Delta Airlines
Sep 15 - Sep 18, Economy
Detroit → Greenville
2h 34m
8:30 AM - 10:24 AM • nonstop
Detroit → Greenville
7h 11m
3:40 PM - 8:11 PM • 1 stop
Delta Airlines
Flying to Greenville soon? We've surfaced some of the most affordable last-minute flights from Detroit to Greenville, ideal for urgent plans or spontaneous trips.
Sep 15 - Sep 18, Economy
Detroit → Greenville
7h 3m
6:00 AM - 10:23 AM • 1 stop
Detroit → Greenville
6h 57m
5:21 PM - 9:38 PM • 1 stop
American Airlines
Sep 14 - Sep 18, Economy
Detroit → Greenville
8h 49m
6:00 AM - 11:29 AM • 1 stop
Detroit → Greenville
5h 54m
1:36 PM - 5:30 PM • 1 stop
American Airlines
Sep 14 - Sep 18, Economy
Detroit → Greenville
2h 29m
4:28 PM - 6:17 PM • nonstop
Detroit → Greenville
6h 58m
7:00 AM - 11:18 AM • 1 stop
Delta Airlines
Sep 14 - Sep 18, Economy
Detroit → Greenville
2h 34m
8:30 AM - 10:24 AM • nonstop
Detroit → Greenville
7h 15m
5:45 AM - 10:20 AM • 1 stop
Delta Airlines
Sep 15 - Sep 18, Economy
Detroit → Greenville
2h 34m
8:30 AM - 10:24 AM • nonstop
Detroit → Greenville
7h 11m
3:40 PM - 8:11 PM • 1 stop
Delta Airlines
Looking for the fastest way to Greenville? These direct flight options from DTW to GSP offer both convenience and value—no layovers, just straight to your destination.
Sep 14 - Sep 18, Economy
Detroit → Greenville
2h 29m
4:28 PM - 6:17 PM • nonstop
Detroit → Greenville
2h 24m
11:04 AM - 12:48 PM • nonstop
Delta Airlines
Sep 15 - Sep 18, Economy
Detroit → Greenville
2h 34m
8:30 AM - 10:24 AM • nonstop
Detroit → Greenville
2h 26m
7:15 AM - 9:01 AM • nonstop
Delta Airlines
Sep 14 - Sep 18, Economy
Detroit → Greenville
2h 21m
7:45 PM - 9:26 PM • nonstop
Detroit → Greenville
2h 26m
7:15 AM - 9:01 AM • nonstop
Delta Airlines
Sep 15 - Sep 18, Economy
Detroit → Greenville
2h 21m
7:45 PM - 9:26 PM • nonstop
Detroit → Greenville
2h 28m
6:57 PM - 8:45 PM • nonstop
Delta Airlines
Sep 14 - Sep 18, Economy
Detroit → Greenville
2h 34m
8:30 AM - 10:24 AM • nonstop
Detroit → Greenville
2h 26m
7:15 AM - 9:01 AM • nonstop
Delta Airlines
FAQs on Detroit to Greenville Flights
What are the airports in Detroit?
DTW
What’s the most popular airline flying from DTW to GSP?
The most popular airline flying from Detroit to Greenville are
Can I fly from DTW to GSP non-stop?
Yes, you can fly DTW to GSP non-stop on
Which airlines fly nonstop between Detroit and Greenville?
The non-stop flights between Detroit and Greenville are .
What’s the earliest departure time from DTW to GSP Airport?
The earliest flight leaves DTW at 6:00 am and lands in GSP - Greenville Spartanburg International
What are the airports in Greenville?
GSP
Can I make changes to my Detroit to Greenville flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from DTW to GSP?
Read the fare rules of the Detroit to Greenville air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Detroit and Greenville?
operate flights between Detroit and Greenville
How long does a flight from Detroit to Greenville take?
It takes approximately 2 hour to fly non-stop from DTW to GSP, which is 508.39 miles by air.
Which airlines provide the cheapest flights from Detroit (DTW) to Greenville (GSP) ?
In the past couple of days, the cheapest tickets to GSP from DTW were found on DL : USD 943
Do I need a passport to fly between DTW and GSP?
No
What’s the latest departure time from DTW to GSP ?
The last flight leaves DTW at 7:45 pm
Detroit (DTW) to Greenville (GSP): Airport Information
| Origin Airport | Detroit Metropolitan Wayne County , Detroit, US |
| Destination Airport | Greenville Spartanburg International , Greenville, US |
| Distance | 508 miles |
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