Search & Compare - Denver to Knoxville Flights & Tickets

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    Cheap flights from Denver to Knoxville (DEN to TYS)

    Looking for a cheap last-minute deal or the best round-trip flight from Denver to Knoxville? Find the biggest savings on one-way and round-trip tickets right here.

    Recent airfare deals on Denver to Knoxville

    United Airlines  UA
    United Airlines
    Denver
    2025-05-27
    Knoxville
    USD 118

    One-way UA Nonstop Economy fare found on 2025-03-24
    United Airlines  UA
    United Airlines
    Denver
    2025-05-27
    Knoxville
    USD 118

    One-way UA Economy fare found on 2025-03-24
    United Airlines  UA
    United Airlines
    Denver
    2025-05-27
    Knoxville
    USD 118

    One-way UA Nonstop Economy fare found on 2025-03-24
    United Airlines  UA
    United Airlines
    Denver
    2025-05-27
    Knoxville
    USD 118

    One-way UA Economy fare found on 2025-03-24
    Delta Airlines  DL
    Delta Airlines
    Denver
    2025-05-27
    Knoxville
    USD 123

    One-way DL Economy fare found on 2025-03-24
    Delta Airlines  DL
    Delta Airlines
    Denver
    2025-05-27
    Knoxville
    USD 123

    One-way DL Economy fare found on 2025-03-24
    Delta Airlines  DL
    Delta Airlines
    Denver
    2025-10-13
    Knoxville
    2025-10-20
    USD 133

    Round Trip DL Economy fare found on 2025-03-23
    Delta Airlines  DL
    Delta Airlines
    Denver
    2025-10-13
    Knoxville
    2025-10-20
    USD 133

    Round Trip DL Economy fare found on 2025-03-23
    United Airlines  UA
    United Airlines
    Denver
    2025-05-27
    Knoxville
    USD 133

    One-way UA Economy fare found on 2025-03-24
    United Airlines  UA
    United Airlines
    Denver
    2025-05-27
    Knoxville
    USD 133

    One-way UA Economy fare found on 2025-03-24


    *Prices are per person and are for e-tickets and include all taxes & fees in USD.
    *Fareleaders always attempts to get accurate pricing, however, prices are not guaranteed.
    *Fareleaders is not seller, we aggregate tones of data for you from other online travel agencies and external sources.

    Facts to know while booking flights from Denver to Knoxville

    What are the airports in Denver?
    What’s the most popular airline flying from DEN to TYS?
    Can I fly from DEN to TYS non-stop?
    Which airlines fly nonstop between Denver and Knoxville?
    What’s the earliest departure time from DEN to TYS Airport?
    What are the airports in Knoxville?
    Can I make changes to my Denver to Knoxville flight tickets or cancel them on FareLeaders.com?
    Can I cancel my flight tickets from DEN to TYS?
    Which airline alliances offer flights from Denver and Knoxville?
    How long does a flight from Denver to Knoxville take?
    Which airlines provide the cheapest flights from Denver (DEN) to Knoxville (TYS) ?
    Do I need a passport to fly between DEN and TYS?
    What’s the latest departure time from DEN to TYS ?

    Flights from Denver to Knoxville

    Origin AirportDenver International , Denver, US
    Destination AirportMcGhee Tyson , Knoxville, US
    Served by AirlinesAmerican Airlines, United Airlines, Delta Airlines
    Lowest PriceUnited Airlines : USD 118
    Distance1162 miles

    Airlines Flying from Denver International

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