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Uncover the best deals on Chicago to St Louis flights by comparing fares from hundreds of airlines and agencies.
Good to Know: Cheapest and Fastest MDW - STL Flights
Useful information for finding best airline tickets from Chicago Midway International to Lambert St Louis International on your next trip.
Cheapest Round Trip Flight
$508
Southwest Airlines
• nonstop
• 1h 55m
Sep 30 – Oct 01
The cheapest round trip flight from Chicago to St Louis (MDW-STL-MDW) is currently $508
Cheapest Direct Flight
$145
United Airlines
• nonstop
• 2h 9m
Sep 30
The cheapest nonstop flight from Chicago to St Louis (MDW-STL) is currently $145
Fastest Flight
1h 50m
The fastest nonstop flight from Chicago to St Louis (MDW-STL) takes 1h 50m
Top Airlines Flying from Chicago to St Louis
Latest Flight Deals from Chicago (MDW) to St Louis (STL)
Compare and book low fare round-trip air tickets from Chicago to St Louis. Ideal for travelers with confirmed return itineraries.
Sep 30 - Oct 01, Economy
Chicago → St Louis
1h 55m
8:30 PM - 9:45 PM • nonstop
Chicago → St Louis
1h 45m
2:00 PM - 3:05 PM • nonstop
Southwest Airlines
Sep 30 - Oct 01, Economy
Chicago → St Louis
6h 40m
8:55 AM - 12:55 PM • 1 stop
Chicago → St Louis
1h 45m
5:25 AM - 6:30 AM • nonstop
Southwest Airlines
Sep 30 - Oct 01, Economy
Chicago → St Louis
5h 45m
4:15 PM - 8:00 PM • 1 stop
Chicago → St Louis
1h 45m
2:00 PM - 3:05 PM • nonstop
Southwest Airlines
Sep 30 - Oct 01, Economy
Chicago → St Louis
1h 55m
8:30 PM - 9:45 PM • nonstop
Chicago → St Louis
5h 35m
5:50 PM - 9:25 PM • 1 stop
Southwest Airlines
Sep 30 - Oct 01, Economy
Chicago → St Louis
5h 45m
4:15 PM - 8:00 PM • 1 stop
Chicago → St Louis
5h 35m
5:50 PM - 9:25 PM • 1 stop
Southwest Airlines
Looking for the fastest way to St Louis? These direct flight options from MDW to STL offer both convenience and value—no layovers, just straight to your destination.
Sep 30 - Oct 01, Economy
Chicago → St Louis
2h 9m
- • nonstop
Chicago → St Louis
2h 9m
- • nonstop
United Airlines
Sep 30 - Oct 01, Economy
Chicago → St Louis
1h 55m
8:30 PM - 9:45 PM • nonstop
Chicago → St Louis
1h 45m
2:00 PM - 3:05 PM • nonstop
Southwest Airlines
Sep 30 - Oct 01, Economy
Chicago → St Louis
1h 50m
10:10 AM - 11:20 AM • nonstop
Chicago → St Louis
1h 50m
10:45 AM - 11:55 AM • nonstop
Southwest Airlines
Sep 30 - Oct 01, Economy
Chicago → St Louis
1h 50m
2:00 PM - 3:10 PM • nonstop
Chicago → St Louis
1h 50m
10:45 AM - 11:55 AM • nonstop
Southwest Airlines
Sep 30 - Oct 01, Economy
Chicago → St Louis
1h 55m
4:40 PM - 5:55 PM • nonstop
Chicago → St Louis
1h 45m
5:25 AM - 6:30 AM • nonstop
Southwest Airlines
FAQs on Chicago to St Louis Flights
What are the airports in Chicago?
ORD,MDW
What’s the most popular airline flying from MDW to STL?
The most popular airline flying from Chicago to St Louis are
Can I fly from MDW to STL non-stop?
Yes, you can fly MDW to STL non-stop on
Which airlines fly nonstop between Chicago and St Louis?
The non-stop flights between Chicago and St Louis are .
What’s the earliest departure time from MDW to STL Airport?
The earliest flight leaves MDW at 8:15 am and lands in STL - Lambert St Louis International
What are the airports in St Louis?
STL
Can I make changes to my Chicago to St Louis flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from MDW to STL?
Read the fare rules of the Chicago to St Louis air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from Chicago and St Louis?
operate flights between Chicago and St Louis
How long does a flight from Chicago to St Louis take?
It takes approximately 1 hour to fly non-stop from MDW to STL, which is 251.08 miles by air.
Which airlines provide the cheapest flights from Chicago (MDW) to St Louis (STL) ?
In the past couple of days, the cheapest tickets to STL from MDW were found on WN : USD 518
Do I need a passport to fly between MDW and STL?
No
What’s the latest departure time from MDW to STL ?
The last flight leaves MDW at 9:3000 pm
Chicago (MDW) to St Louis (STL): Airport Information
| Origin Airport | Chicago Midway International , Chicago, US |
| Destination Airport | Lambert St Louis International , St Louis, US |
| Distance | 251 miles |
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