Cheap Flight Tickets from San Francisco (SFO) to Des Moines (DSM), Starting at $341

Good to Know: Cheapest and Fastest SFO - DSM Flights

Useful information for finding best airline tickets from San Francisco International to Des Moines International on your next trip.

Cheapest Round Trip Flight

$341

WN Southwest Airlines • 2 stops • 14h 10m

May 07 – May 17

The cheapest round trip flight from San Francisco to Des Moines (SFO-DSM-SFO) is currently $341

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Cheapest One way Flight

$350

WN Southwest Airlines • 1 stop • 8h 30m

May 04

The cheapest one way flight from San Francisco to Des Moines (SFO-DSM) is currently $350

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Fastest Flight

8h 30m

The fastest nonstop flight from San Francisco to Des Moines (SFO-DSM) takes 8h 30m

Top Airlines Flying from San Francisco to Des Moines

Southwest Airlines-WN

Southwest Airlines

Delta Airline, DL

Delta Airlines

United Airlines, UA

United Airlines

American Airlines, AA

American Airlines

Alaska Airlines -AS

Alaska Airlines

Latest Flight Deals from San Francisco (SFO) to Des Moines (DSM)

Compare and book low fare round-trip air tickets from San Francisco to Des Moines. Ideal for travelers with confirmed return itineraries.

May 07 - May 17, Economy
WN
San Francisco → Des Moines
14h 10m
1:00 PM - 11:50 PM • 2 stops
WN
San Francisco → Des Moines
10h
6:45 AM - 10:45 AM • 1 stop
$341
Southwest Airlines
May 07 - May 17, Economy
WN
San Francisco → Des Moines
9h
10:35 AM - 6:15 PM • 1 stop
WN
San Francisco → Des Moines
14h
10:25 AM - 5:05 PM • 2 stops
$341
Southwest Airlines
May 07 - May 17, Economy
DL
San Francisco → Des Moines
13h 53m
11:45 PM - 10:18 AM • 1 stop
DL
San Francisco → Des Moines
10h 9m
7:50 PM - 11:59 PM • 1 stop
$496
Delta Airlines
May 06 - May 16, Economy
WN
San Francisco → Des Moines
17h 5m
11:25 AM - 11:50 PM • 2 stops
WN
San Francisco → Des Moines
9h 5m
6:40 AM - 10:25 AM • 1 stop
$502
Southwest Airlines
May 07 - May 17, Economy
DL
San Francisco → Des Moines
30h 44m
12:40 AM - 9:24 PM • 1 stop
DL
San Francisco → Des Moines
10h 9m
7:50 PM - 11:59 PM • 1 stop
$551
Delta Airlines
May 06 - May 16, Economy
AA
San Francisco → Des Moines
10h 17m
8:15 AM - 4:32 PM • 1 stop
AA
San Francisco → Des Moines
10h 19m
6:26 PM - 10:45 PM • 1 stop
$680
American Airlines

Fly from San Francisco to Des Moines with the Best Airfare Deals on FareLeaders

Looking for a cheap last-minute deal or the best round-trip flight from San Francisco to Des Moines? Find the biggest savings on one-way and round-trip tickets right here.

FAQs on San Francisco to Des Moines Flights

What are the airports in San Francisco?
SFO
What’s the most popular airline flying from SFO to DSM?
The most popular airline flying from San Francisco to Des Moines are
Can I fly from SFO to DSM non-stop?
NO
Which airlines fly nonstop between San Francisco and Des Moines?
The non-stop flights between San Francisco and Des Moines are .
What’s the earliest departure time from SFO to DSM Airport?
The earliest flight leaves SFO at 12:40 am and lands in DSM - Des Moines International
What are the airports in Des Moines?
DSM
Can I make changes to my San Francisco to Des Moines flight tickets or cancel them on FareLeaders.com?
No. We are an airfare comparison site. All the tickets are booked by the travel agent offering the flight deal and any changes or cancellations to be made are directly done directly by them or the airlines.
Can I cancel my flight tickets from SFO to DSM?
Read the fare rules of the San Francisco to Des Moines air tickets booked. Some airlines allow you to cancel the tickets within a stipulated time period with a cancellation fee.
Which airline alliances offer flights from San Francisco and Des Moines?
operate flights between San Francisco and Des Moines
How long does a flight from San Francisco to Des Moines take?
It takes approximately 4 hour to fly non-stop from SFO to DSM, which is 1549.07 miles by air.
Which airlines provide the cheapest flights from San Francisco (SFO) to Des Moines (DSM) ?
In the past couple of days, the cheapest tickets to DSM from SFO were found on WN : USD 350
Do I need a passport to fly between SFO and DSM?
No
What’s the latest departure time from SFO to DSM ?
The last flight leaves SFO at 11:45 pm

San Francisco (SFO) to Des Moines (DSM): Airport Information

Origin Airport San Francisco International , San Francisco, US
Destination Airport Des Moines International , Des Moines, US
Distance 1549 miles

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